|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | A | T | A | G | H | V | D | H | G | K | T | T | L | L | Q | A | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | G | V | N | A | D | R | L | P | E | E | K | K | R | G | M | T | I | D | L | G | Y | A | Y | W | P | Q | P | D | G | R | V | P | G | F | I | D | V | P | G | H | E | K | F | L | S | N |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |
|   |   |   |
|
|   |   |
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|   |
|
|
|
|
|   |
|   |
|
|   |   |
|
|   |
|   |   |   |
|   |
|   |   |
|   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |
|
| . | . | . | . |   |   |   |   |   |   | . |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|
Template Sequence |   |
F | A | I | I | S | H | P | D | A | G | K | T | T | L | T | E | K | L | L | L | F | G | G | A | I | Q | L | A | G | T | I | K | S | R | H | A | T | S | D | W | X | E | L | E | K | Q | V | T | T | S | V | . |
. |
. |
. |
X | Q | F | P | Y | K | . |
D | Y | L | I | N | L | L | D | T | P | G | H | A | D | F | T | E | D |
Template Known Secondary structure |   |
 |  |  |  |
|
| T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  | T |
|
|
|
|  |  |  |  |  |  |  | T | T |
|
|
| S | S |  | . | . | . | . |  |  |  |  |  | T | . | T |  |  |  |  |  |  |
|
|
|
| S | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  | . | . | . | . |  |  |  |  |  |
| . |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
13 | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
|
|
|
. | . | . | . | . | . | |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
  |
  |   |
68 | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
M | L | A | G | V | G | G | I | D | H | A | L | L | V | V | A | C | D | D | G | V | M | A | Q | T | R | E | H | L | A | I | L | Q | L | T | G | N | P | M | L | T | V | A | L | T | K | A | D | R | V | D | E | A | R | V | D | E | V | E | R | Q | V | K | E | V | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
|
|   |
|   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|   |
|
|
|   |
|   |   |   |
|
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |
|   |   |
|   |   |   |   |
|
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |   |
|
|   |   |   |
|   |
|
|
|
|
|
|
|   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |
| . |   |
|
|
|
|
|
|
|
|
|   |   |
|   | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |
Template Sequence |   |
T | Y | R | T | L | T | A | V | D | S | A | L | X | V | I | D | A | A | K | G | V | E | P | R | T | I | K | L | X | E | V | C | R | L | R | H | T | P | . |
I | X | T | F | I | N | K | X | D | R | D | T | R | P | . |
S | I | E | L | L | D | E | I | E | S | I | L | R | I | H | C | A | P | V | T | W | P | I | G | X | G |
Template Known Secondary structure |   |
 |  |  |  | G | G | G |
| S |  |  |  |  |  |  |  | T | T | T | B | S |
|  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
| . |  |  |  |  |  |  |
| T | T | S |
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  | S |  |  |  |  | S |
| T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |  |  |  |  |  |
|
|
|
|
|
|
|
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | |
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
134 | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | E | Y | G | F | A | E | A | K | L | F | I | T | A | A | T | E | G | R | G | M |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |
|
|   |
|
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|
|   |   |   |   |
|
|
Template Sequence |   |
K | Y | F | K | G | I | Y | H | L | I | E | D | A | I | Y | L | Y | Q | P | S | E | R | I | E | G | I | N | N | P | E | L | D | K | K | L | G | D | L | A | S | E | L | R | N | E | I | E | L | V | K | G | A | S | H | P | F | E | R | E | G | Y | L | K | G | E | L | T | P | I | F | F | G | S | A | I | N | N | F | G | V |
Template Known Secondary structure |   |
T |
|
|
|  |  |  |  | T | T | T | T |  |  |  |  |
|
|
|
|
|  |  |  |
| T | T |
|  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  | T | S |  |  |  |  |  |  |
| B | G | G | G | T | B | S |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
174 | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . |
  |
  |   |
155 | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | |
|
|
. | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | A | L | R | E | H | L | L | Q | L | P | E | R | E | H | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | Q | H | S | F | R | L | A | I | D | R | A | F | T | V | . |
. |
. |
K | G | A | G | L | V | V | T | G | T | A | L | S | G | E | V | K | V | G | D | S | L | W | L | T | G | V | N | K | P | M | R | V | R | A | L |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |
|
|   |
|
|
|
|
|   |
| . | . | . |   |
|   |
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
|
|   |
|   |
|   |
|   |   |   |   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|   |
|   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Template Sequence |   |
G | E | L | L | D | A | F | V | K | E | A | P | P | P | Q | G | R | E | T | N | S | R | L | V | K | P | E | E | E | K | F | S | G | F | V | F | K | I | Q | A | N | X | D | P | G | H | R | D | R | I | A | F | L | R | I | A | S | G | Q | Y | Q | K | G | X | K | A | Y | H | V | R | L | K | K | E | I | Q | I | N | N | A |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | S |
|
|
|
|
|  |  | B | S | S |
|  |  |
| T | T |
| S | S |
|  |  |  |  |  |  |  |  |  |
|
| S | T | T |
|
|
|  |  |  |  |  |  |  |  |  | S |
|  |  | T | T |  |  |  |  |  | G | G | G | T |  |  |  |  |  | S | S |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
262 | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . |
  |
  |   |
222 | |
|
|
|
. | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . |
Predicted Secondary structure |   |
 | . | . | . | . |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | . |
. |
. |
. |
A | Q | N | Q | P | T | E | T | A | N | A | G | Q | R | I | A | L | N | I | A | G | D | A | E | K | E | Q | I | N | R | G | D | W | L | L | A | D | V | P | P | E | P |
Query Conservation |   |
| . | . | . | . |   |   |   |   |   |
|   |   |
|   |
|
|   |
|
|
|
|
|
|   |
|   |
|   |   |   |   |
|   |
|
|   |
|
|   |   |   |   |   |   |   |   |
Alig confidence |   |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |   |
|   |   |
|   |
|
|
|
|
|   |
| . | . | . | . | . |   |   |
|   |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |
Template Sequence |   |
L | T | F | X | A | G | K | R | E | N | A | E | E | A | W | P | G | D | I | I | G | L | . |
. |
. |
. |
. |
H | N | H | G | T | I | Q | I | G | D | T | F | T | Q | G | E | R | F | K | F |
Template Known Secondary structure |   |
B |
|
| B | T | T |
| S | S |
|
| S |  |  |
| T | T |
|  |  |  |  | . | . | . | . | . |  |  | S | S |
|
|
| T | T |
|  |  |  | S | S |
|
|
|
| B |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . | . |  |
|
|
|
|  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
342 | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . |
  |