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Job DescriptionP0A6K6
Confidence99.96%DateWed Jan 25 15:20:15 GMT 2012
Rank20Aligned Residues248
% Identity19%Templatec2xrgA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:ectonucleotide pyrophosphatase/phosphodiesterase family PDBTitle: crystal structure of autotaxin (enpp2) in complex with the2 ha155 boronic acid inhibitor
Resolution3.20 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   23......30.........40.........50.........60.........70 .........80.........90.........100.
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Query Sequence  FGDVGADTLGHIAEACAKGEADNGRKGPLNLPNLTRLGLAKAHEGSTG. FIPAGMDGNAEVIGAYAWAHEMSSGKDTPSG
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Template Sequence  AGFVRPPLIIFSVDGFRASYMKKGSKV. . . MPNIEKLRSCGTHAPYMRPVYPTKTFPNLYTL. ATGLYPESH. . . . . . . .
Template Known Secondary structure  TT
SS

T

GGGGGS
TTT...SS
S


SS
S.
S
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   158.160.........170.........180.... .....190.........200.........210...... ...220.....
 
   102.......110.........120.........130.........140.........150.........160.........170.........180.
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Query Sequence  HWEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEHMKTGKPIFYTSADSVFQIACH
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . GIVGNSMYDPVFDASFHLRGREKFN
Template Known Secondary structure  .......................................................S


SSTTTT
SSSSGGG
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   226...230.........240.........250
 
   182.......190.........200.........210.........220.........230.........240.........250.........260.
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Query Sequence  EETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIGDKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIA
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Template Sequence  HRWWGGQPLWITATKQGVRAGTFFWSVS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TTS

S

TTT

B





TT....................................................
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   251........260.........270........
 
   262.......270.........280.........290 .........300.........310..... ....320.........330.......
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Query Sequence  DIYANCGITKKVKATGLDALFDATIKEMK. . EAGDNTIVFTNFVDFDSSWGHRRDV. . AGYAAGLELFDRRLPELMSLLR
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Template Sequence  . . . . . . . . . . . . . . IPHERRILTILQWLSLPDNERPSVYAFYSEQPDFS. GHKYGPFGPEMTNPLREIDKTVGQLMDGLK
Template Known Secondary structure  ..............S
TTS
TTT

S.
TT
GGG
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   279280.........290.........300.........310... ......320.........330.........340...
 
   338.340.........
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Query Sequence  . . . . . DDDILILTADHG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  QLRLHRCVNVIFVGDHGMEDVTCDRTEFLSNYLTNVDDITLVPGTLGRIRAKYDPKTIIAALTCKKPDQHFKPYMKQHLP
Template Known Secondary structure  TT
TTT
S




SSSGGGT
S

TT
BS


TTSS
STT

GGGS
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   344.....350.........360.........370.........380.........390.........400.........410.........420...
 
   350.........360 .........370.........380.........390....... ..
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . CDPTWTGTDHT. . REHIPVLVYGPKVKPGSLGHRETFADIGQTLAKYFGT. SD
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Template Sequence  KRLHYANNRRIEDIHLLVDRRWHVARKPFQGDHGFDNKVNSMQTVFVGYGPTFKYRTKVPPFENIELYNVMCDLLGLKPA
Template Known Secondary structure  GGG


SSTTS
S
TT
S





S
TT
GGG
B
SSSB
SS
B


GGGT



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   430.........440.........450.........460.........470.........480.........490.........500.........
 
   400....
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Query Sequence  MEYGK
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Template Sequence  PNNGT
Template Known Secondary structure  S
SS
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   522....
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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