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Job DescriptionP19319
Confidence100.00%DateThu Jan 5 11:37:17 GMT 2012
Rank15Aligned Residues647
% Identity26%Templatec2iv2X_
PDB info PDB header:oxidoreductaseChain: X: PDB Molecule:formate dehydrogenase h; PDBTitle: reinterpretation of reduced form of formate dehydrogenase h2 from e. coli
Resolution2.27 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   44.....50.........60.........70.........80.........90.........100....... ..110.........
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Query Sequence  KIVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWYLYSAN. . . . RLKYPLIRKRLI
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Template Conservation 
 
 
 
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Template Sequence  KKVVTVCP. YCASGCKINLVVDNGKIVRAEAA. QGKTNQG. . . . . . . TLCLKGYYGWDFINDTQILTPRLKTPMIR. . . .
Template Known Secondary structure 
S.SBTT

TT
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TTTTT.......


TTGGGG


SSS
B

S

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   2....... 10.........20.........30.. ....... 40.........50.........60........
 
   120.........130.........140.........150.........160.........170.........180.........190.........
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Query Sequence  ELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIRSNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVS
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Template Conservation  ................................    
    






  

  
  
    
   
             
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . RQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDAIQTTGSSRGTGNET
Template Known Secondary structure  ................................
STTS




GGG

SSTT
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   6970.........80.........90.........100.........110......
 
   200.........210.........220..... ....230.........240.........250.........260.........270.......
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Query Sequence  YAAGTRYLSLLGGTCLSFYDWYCDLP. . PASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGTK
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Template Conservation                                     
         
   

 

  
 
              
   
 
Template Sequence  NYVMQKFARAVIGTNNVDCCARVHGPSVAGLHQSVGNGAMSNAINEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAK
Template Known Secondary structure  TT




SS



SSS
SS

S
SS
GGGGGG
SS


TT
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   117..120.........130.........140.........150.........160.........170.........180.........190......
 
   278.280.........290.........300.........310.........320.........330.........340.........350.......
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Query Sequence  TIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRYSDMPMLVMLEPRDDGSYVPGRMI
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Template Sequence  IIVCDPRKIETARIADMHIALKNGSNIALLNAMGHVIIEENLYDK. . . . . . AFVASRTEG. . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 
SS

T
S


TT
TT
S
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   198.200.........210.........220.........230.........240.. .......250.
 
   358.360.........370.........380.........390.........400.........410.........420.........430.......
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Query Sequence  RASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSIGFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGI
Query Conservation 
  
               

 
  
    
    
                                            
Template Conservation  ................................................................................
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  ................................................................................
Template Predicted Secondary structure  ................................................................................
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   438.440.........450.........460.........470.........480.........490.........500.........510.......
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Query Sequence  ENPHFRSVKHNPVLVRQLPVKNLTLVDGNTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGEQITGVPRQY
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Template Conservation  ....................................

 
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FEEYRKI. . . . . . . . . . . . . . . . . . VEGYTPESVEDITGVSASE
Template Known Secondary structure  ......................................................T

SGGG


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   252...... .260.........270.......
 
   518.520.........530.........540.........550.........560.........570.........580.........590.......
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Query Sequence  IETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGCVGQSGGGWAHYVGQEKLRPQTGWLPLAFALD
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Template Conservation 
  

     
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Template Sequence  IRQAARMYAQA. . . . . KSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAG. . . . . . . . . VNPVRGQNNVQGACD
Template Known Secondary structure  S.....SSTTGGGSSSTT
SSSTT
S.........
SBTT
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   278.280........ .290.........300.........310.........320........ .330.........340...
 
   598.600.........610.........620.........630.........640.........650.........660.........670.......
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Query Sequence  WNRPPRQMNSTSFFYNHSSQWRYEKVSAQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLGIKAEADKAGL
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Template Conservation   
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Template Sequence  MGALPDTYPGYQYVKDPANREKFAKAWGVESLP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  TT
BTTGGGTT
TT
S


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   344.....350.........360.........370......
 
   678.680.........690.........700.........710.........720.........730.........740.........750.......
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Query Sequence  SPTEFTAQALKSGDLRMACEQPDSSSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQGEELGASDGIKPEEVEWQ
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Template Conservation  ..........                
 

 
     

    
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Template Sequence  . . . . . . . . . . AHTGYRISELPHRAAHGEVRAAYIMGEDPLQTDAELS. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . A
Template Known Secondary structure  ..........
S



GGGTTS

S

SSS................................
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   377..380.........390.........400.........410... .
 
   758.760.........770.........780.........790.........800.........810.........820.........830.......
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Query Sequence  TAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMNTSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQVC
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Template Sequence  VRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGEHEG. VFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPM
Template Known Secondary structure  SSSB

T
SB

BTTB
.
TTS


S

SSS
B
TT


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   415....420.........430.........440.........450... ......460.........470.........480.........490...
 
   838.840.........850.........860.........870.........880.........890.........900.........910.......
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Query Sequence  VGHLGKETDVVLQPLLHDSPAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGKGIS
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Template Conservation                       ...................................   
 
   
              
Template Sequence  HYNNTQEIWDELRHLCPDFYG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . ATYEKMGELGFIQWPCRDTSDADQ
Template Known Secondary structure 

SS
TTTTT...................................

TTT

S



SSTT

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   494.....500.........510.... .....520.........530........
 
   918.920.........930.........940.........950.........960.........970.........980.........990.......
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Query Sequence  WNTQDEIDFLGKLNYTKRDGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQALGEITGREHTHLALHKEDEKIRFR
Query Conservation                                                
                                 
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Template Conservation        ..........................................................................
Template Sequence  GTSYLF. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure  B
SSS
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Template Predicted Secondary structure 





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   539540....
 
   998.1000.........1010.........1020.........1030.........1040.........1050.........1060.........1070.......
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Query Sequence  DIQAQPRKIISSPTWSGLESDHVSYNAGYTNVHELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIP
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . KEKFDTPNGLAQFFT. . . . . . . . . . . . CDWVAPIDKL. . . . . . . . .
Template Known Secondary structure  ..................................SS

SSTTS



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SS

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   545....550......... 560.........
 
   1078.1080.........1090.... .....1100.........1110..... ....1120.........1130.........1140.........1150....
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Query Sequence  PNGFPEKALNFLTPHQK. . WGIHSTYSENLLMLTLSRGGP. IVWISETDARELTIVDNDWVEVFNANGALTARAVVSQRV
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Template Conservation  ...   


 
 
          
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Template Sequence  . . . TDEYPMVLSTVREVGHYSCRSMTG. NCAALAALADEPGYAQINTEDAKRLGIEDEALVWVHSRKGKIITRAQVSDRP
Template Known Secondary structure  ...
SSS



TT

SS
TTGG.GSTT

SS
T

TT

SS
SSS
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   570.........580.........590... ......600.........610.........620.........630.........640.....
 
   1155....1160.......
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Query Sequence  PPGMTMMYHAQER
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Template Conservation    
 
    
   
Template Sequence  NKGAIYMTYQWWP
Template Known Secondary structure 
TT





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   646...650........
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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