|   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | |
|
. | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | I | I | I | G | G | G | A | T | G | A | G | I | A | R | D | C | A | L | R | . |
. |
G | L | R | V | I | L | V | E | R | H | D | I | A | T | G | A | T | G | R | N | H | G | L | L | H | S | G | A | R | Y | A | V | T | D | A | E | S | A | R | E | C | I | S | E | N | Q | I | L | K | R | I | A | R | H | C | V | E | P |
Query Conservation |   |
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |   | . | . |
|
|   |
|   |
|
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|   |
|
|
|   |   |
|   |   |
|
|
|   |   |   |
|   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | L | V | I | G | A | G | P | A | G | L | V | F | A | S | Q | L | K | Q | A | R | P | L | W | A | I | D | I | V | E | K | N | D | E | Q | E | V | L | G | W | G | V | V | L | P | G | R | P | G | Q | H | P | A | N | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | Y | L | D | A | P | E | R | L | N | P | Q | F |
Template Known Secondary structure |   |
 |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |
| S | S |
| T | T |
|
|
|
| S |  |  |  |  |  | S |
| T | T | T |
| T | T |
| G | G | . | . | . | . | . | . | . | . | . | . | . | G | G | S | S |
| G | G | G | G |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . |
  |
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | N | G | L | F | I | T | L | P | E | D | D | L | S | F | Q | A | T | F | I | R | A | C | E | E | A | G | I | S | A | E | A | I | D | P | Q | Q | A | R | I | I | E | P | A | V | N | P | A | L | I | G | A | V | K | V | P | D | G | T | V | D | P | F | R | L | T | A | A | N | M | L | D | A | K | E | H | G | A | V | I |
Query Conservation |   |
  |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | E | D | F | K | L | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
H | H | N | E | P | S | L | X | S | T | G | V | L | L | C | G | V | E | R | R | G | L | V | H | A | L | R | D | K | C | R | S | Q | G | I | A | I |
Template Known Secondary structure |   |
 |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  | S | S | S |  |  |  |
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
72 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | |
|
. | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  | . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | T | A | H | E | V | T | G | L | I | R | E | G | A | T | V | C | G | V | R | V | R | N | H | L | T | G | E | T | Q | A | L | H | A | P | V | V | V | N | A | A | G | I | W | G | . |
. |
Q | H | I | A | E | Y | A | D | L | R | I | R | M | F | P | A | K | G | S | L | L | I | M | D | H | R | I | N | Q | H | V | I | N |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |   |
| . | . |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | F | E | S | P | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | E | H | G | E | L | P | L | A | D | Y | D | L | V | V | L | A | N | G | V | N | H | K | T | A | H | F | T | E | A | L | V | P | Q | V | D | Y | G | R | N | K | Y | I | W | Y | G | T | S | Q | L | F | D | Q | X | N | L | V |
Template Known Secondary structure |   |
 | T | T |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S | G | G | G |
|
| G | G | G |
| S |  |  |  |  |
|
| G | G | G | G | G | T |
|
| S | S | G | G | G |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| S | S |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
116 | . | . | . | 120 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . |
  |
  |   |
247 | . | . | 250 | . | . | . | . | . | . | . | . | |
|
|
|
. | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  | . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | C | R | K | P | S | D | A | D | I | L | V | . |
. |
. |
. |
P | G | D | T | I | S | L | I | G | T | T | S | L | R | I | D | Y | N | E | I | D | D | N | R | V | T | A | E | E | V | D | I | L | L | R | E | G | E | K | L | A | P | V | M | A | K | T | R | I | L | R | A | Y | S | G | V | R | P | L | V | A | S | D | D |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | R | T | H | G | K | D | I | F | I | A | H | A | Y | K | Y | S | D | T | X | S | T | F | I | V | E | C | S | E | E | T | Y | A | R | A | R | L | G | E | X | S | E | E | A | S | A | E | Y | V | A | K | V | F | Q | A | E | L | G | G | H | G | L | V | S | Q | P | G | L | G | W | R | N | F | X | T | L | S | H | D | R |
Template Known Secondary structure |   |
 |  |  |  | T | T |  |  |  |  |  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |
|  |  |  |  |  |  | T | T | S | S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | T | T |
|
|
| B |
|
| T | T | T |
| S |  |  |  |  |  |
|
|
| S |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
179 | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . |
  |
  |   |
323 | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | P | S | G | R | N | V | S | R | G | I | V | L | L | D | H | A | E | R | D | G | L | D | G | F | I | T | I | T | G | G | K | L | M | T | Y | R | L | M | A | E | W | A | T | D | A | V | C | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
| . | . | . | . | . |
|   |
|
|
|
|
|
|
|   |   |   |
| . | . | . | . |   |   |
|   |
|   |   |   |
|
|   |
|
|   |   |
|
|   |   |
|   |   |
Template Sequence |   |
C | H | D | G | K | . |
. |
. |
. |
. |
L | V | L | L | G | D | A | L | Q | S | G | H | F | . |
. |
. |
. |
S | I | G | H | G | T | T | X | A | V | V | V | A | Q | L | L | V | K | A | L | C | T |
Template Known Secondary structure |   |
S |  |  | T | T | . | . | . | . | . |  |  |  |
| G | G | G | T |
|
|
|
| G | . | . | . | . | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
259 | 260 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 270 | . | . | . | . | . | . | |
|
|
|
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . |
  |