|   |
7 | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | |
. | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | S | S | D | V | I | I | I | G | G | G | A | T | G | A | G | I | A | R | D | C | A | L | R | G | L | R | V | I | L | V | E | R | H | D | I | A | T | G | A | T | G | R | N | H | G | L | L | H | S | G | A | R | Y | A | V | T | . |
D | A | E | S | A | R | E | C | I | S | E | N | Q | I | L | K | R | I | A | R | H | C |
Query Conservation |   |
  |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|
|   |   |
|
|   |
|   |
|
|
|   |   |
|   |
|   |
|
|
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |   |
|
|   |   |
|   |   |
|   |
|
|
|   |   |
|   |   |   |
|
|
|   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
Template Sequence |   |
E | E | L | D | L | L | I | I | G | G | G | I | T | G | A | G | V | A | V | Q | A | A | A | S | G | I | K | T | G | L | I | E | X | Q | D | F | A | E | G | T | S | S | R | S | T | K | L | V | H | G | G | I | R | Y | L | K | T | F | D | V | E | V | V | A | D | T | V | G | E | R | A | V | V | Q | G | I | A | P | H | I |
Template Known Secondary structure |   |
S |
| B | S |  |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |
| S | S | S | T | T |
| S | G | G | G | S | S |
| S |  |  |
|
|
| G | G | G | G | G | G | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
17 | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . |
  |
  |   |
86 | . | . | . | 90 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | |
. | . | . | . | . | 150 | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
| . |
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | E | P | T | N | G | L | F | I | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | E | D | D | L | S | F | Q | A | T | F | I | R | A | C | E | E | A | G | I | S | A | E | A | I | D | P | Q | Q | A | R | I | I | E | P | A | V | N | P | A | L | I | G | A | V | K | V | P | . |
D | G | T | V | D | P | F | R | L |
Query Conservation |   |
  |   |   |   |
|   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
P | K | P | D | P | X | L | L | P | I | Y | E | D | E | G | A | T | T | F | N | X | F | S | V | K | V | A | X | D | L | Y | D | K | L | A | N | V | T | G | T | K | Y | E | N | Y | T | L | T | P | E | E | V | L | E | R | E | P | F | L | K | K | E | G | L | K | G | A | G | V | Y | L | D | F | R | N | N | D | A | R | L |
Template Known Secondary structure |   |
S |  |  |
|
|  |  |  |  |  |  | S | S | S | S | S |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S | S | T | T |
|
|  |  |  |
|  |  |  |  |  |  |  |
| T | T | S |
|
| T | T |  |  |  |  |  |  |  |
|
|  |  |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
97 | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | |
|
|
. | . | . | . | . | . | . | . | 230 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . |
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | A | A | N | M | L | D | A | K | E | H | G | A | V | I | L | T | A | H | E | V | T | G | L | I | R | E | G | A | T | V | C | G | V | R | V | R | N | H | L | T | G | E | T | Q | A | L | H | A | P | V | V | V | N | A | A | G | I | W | G | Q | H | I | A | E | Y | A | D | . |
. |
. |
L | R | I | R | M | F | P | A | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |   |
|   |   |
|   |   |   |   |
| . | . | . |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |
|
|
|
|
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
Template Sequence |   |
V | I | D | N | I | K | K | A | A | E | D | G | A | Y | L | V | S | K | X | K | A | V | G | F | L | Y | E | G | D | Q | I | V | G | V | K | A | R | D | L | L | T | D | E | V | I | E | I | K | A | K | L | V | I | N | T | S | G | P | W | V | D | K | V | R | N | L | N | F | T | R | P | V | S | P | K | X | R | P | T | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  | S | S |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  | B | S |
|  |  |  |
|
| G | G | G |  |  |  |  |  | T | T |
|
| S | S |
|
|
|
|
| B |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
177 | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . |
  |
  |   |
231 | . | . | . | . | . | . | . | . | 240 | . | |
|
|
|
. | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
. | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
Query Sequence |   |
G | S | L | L | I | M | D | H | R | I | N | . |
. |
. |
. |
Q | H | V | I | N | R | C | R | K | P | S | D | A | D | I | L | V | P | G | D | T | I | S | L | I | G | T | T | S | L | R | I | D | Y | N | E | I | D | D | N | R | V | T | A | E | E | V | D | I | L | L | R | E | G | E | K | L | A | P | V | . |
. |
M | A | K |
Query Conservation |   |
|   |   |   |   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |
|   | . | . |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
Template Conservation |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   |
|   |   |   |   |   | . |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
G | I | H | L | V | V | D | A | K | K | L | P | V | P | Q | P | T | Y | F | D | T | G | K | Q | D | G | R | X | V | F | A | I | P | R | E | N | K | T | Y | F | G | T | T | D | T | D | Y | Q | . |
G | D | F | T | D | P | K | V | T | Q | E | D | V | D | Y | L | L | D | V | I | N | H | R | Y | P | E | A | N | I | T | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | G | G | G | S |
|
| S | S |
|  |  |  |  |
| S | S | S | S | S |
|  |  |  |  |  |  |  | T | T |  |  |  |  |
|
|
|
|  |  |
|
| . | S |
| S | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T | T |
|
|
| G |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | |
. | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . |
  |
  |   |
305 | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | |
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
T | R | I | L | R | A | Y | S | G | V | R | P | L | V | A | S | D | D | D | P | S | G | R | N | V | S | R | G | I | V | L | L | D | H | A | E | R | D | G | L | D | G | F | I | T | I | T | G | G | K | L | M | T | Y | R | L | M | A | E | W | A | T | D | A | V | C | R | K | L | G | N | T | . |
. |
. |
. |
. |
R | P | C |
Query Conservation |   |
  |   |
|   |   |   |   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
Template Conservation |   |
  |
|
|   |   |   |
|
|
|
|
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | D | I | E | A | S | W | A | G | L | R | P | L | L | I | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | S | L | E | R | E | P | D | G | L | L | T | L | S | G | G | K | I | T | D | Y | R | K | X | A | E | G | A | L | R | L | I | R | Q | L | L | K | E | E | Y | G | I | E | T | K | E | I |
Template Known Secondary structure |   |
G | G |
|
|  |  |  |  |  |  |  |
|
| B |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
336 | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
  |
  |   |
380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | |
|
|
|
|
|
|
|
|
. | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 |
Predicted Secondary structure |   |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | T | A | D | L | A | L | P | G | S | Q | E | P | A | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
V | T | L | R | K | V | I | S | L | P | A | P | L | R | G | S | A | V | Y | R | H | G | D | R | T | P | A | W | L | S | E | G | R | L | H | R | S | L | V | C | E | C | E | A | V | T | A | G | E | V | Q | Y | A | V | E | N |
Query Conservation |   |
  |
|   |   |   |   |
|   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |
|
|   |   |
|
|   |   |
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |
|
|   |   |
Template Sequence |   |
D | S | K | K | Y | Q | I | S | G | G | N | F | D | P | T | K | L | E | E | T | V | T | E | L | A | K | E | G | V | A | A | G | L | E | E | E | D | A | T | Y | I | A | D | F | Y | G | T | N | A | R | R | I | F | E | . |
L | A | K | E | X | A | P | Y | P | G | L | S | L | A | E | S | A | R | L | R | Y | G | L | E | E |
Template Known Secondary structure |   |
| T | T | T |
|
|
| T | T |
|
| S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  | . |  |  |  | T |
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | |
. | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . |
  |
  |   |
451 | . | . | . | . | . | . | . | |
. | 460 | . | . | . | . | . | . | . | |
. | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  | . |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | N | V | N | S | L | L | D | . |
L | R | R | R | T | R | V | G | M | . |
G | T | C | Q | G | E | L | C | A | C | R | A | A | G | L | L | Q | R | F | N | V | T | T | S | A | Q | S | I | E | Q | L | S | T | F | L | N |
Query Conservation |   |
|   |   |   |   |   |   |
| . |
|
|
|
|
|
|   |
|
| . |
|   |
|
|
|   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |
|   |
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
|
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |
Template Sequence |   |
E | X | V | L | A | P | G | D | Y | L | I | R | R | T | N | H | L | L | F | E | R | D | Q | L | D | E | I | K | Q | P | V | I | D | A | I | A | E | Y | F | G | W | T | E | E | E | K | A | Q | Q | T | K | R | L | E | A |
Template Known Secondary structure |   |
S |
|
|
| S |  |  |  |  |  |  | T | T | S | S |  |  |  |  |
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
539 | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . |
  |