|   |
2 | . | . | . | . | . | . | . | 10 | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 20 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
. | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
Query Sequence |   |
R | L | W | L | I | R | H | G | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | Q | A | N | I | D | G | L | Y | S | G | H | A | . |
. |
. |
. |
. |
. |
. |
. |
P | T | P | L | T | A | R | G | I | E | Q | A | Q | N | L | H | T | L | L | . |
. |
H | G | V | S | F | D |
Query Conservation |   |
  |
|   |
|
|
|
|
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . |
|   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |
| . | . |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |
|
|
|   |   |
|   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |
|
Template Sequence |   |
G | I | L | V | I | R | H | G | E | R | V | D | Q | V | F | G | K | S | W | L | Q | Q | C | T | T | A | D | G | K | Y | Y | R | P | D | L | N | F | P | R | S | L | P | R | R | S | N | G | I | K | D | F | E | N | D | P | P | L | S | S | C | G | I | F | Q | A | R | L | A | G | E | A | L | L | D | S | G | V | R | V | T |
Template Known Secondary structure |   |
 |  |  |  |  |  |
|
|
| B |  |  |  |  |  |
| T | T |  |  |  |  | T | B |
| T | T | S |
| B |
|
| S | S | T | T | S |
| S |
|
|
|
|
| S | S |
| G | G | G | G | T | T | S |
|
| B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . |
  |
  |   |
49 | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | |
|
|
|
. | . | . | . | . | . | . | . | . | 80 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|
|
|
|  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | L | C | S | E | L | E | R | A | Q | H | T | A | R | L | V | L | S | D | R | Q | . |
. |
. |
. |
L | P | V | Q | I | I | P | E | L | N | E | . |
. |
. |
. |
. |
M | F | F | G | D | W | E | M | R | H | H | R | D | L | M | Q | E | D | A | E | N | Y | S | A | W | C | N | D | W | Q | H | A | I | P | T | N | G | E |
Query Conservation |   |
  |
|   |
|
|
|
|   |
|
|   |
|
|
|   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
| . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|
|
|
|   |
|
|   |
|
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
A | V | F | A | S | P | A | L | R | C | V | Q | T | A | K | H | I | L | E | E | L | K | L | E | K | K | L | K | I | R | V | E | P | G | I | F | E | W | M | K | W | E | A | S | K | A | T | L | T | F | L | T | L | E | E | L | K | E | A | N | F | N | V | D | L | D | Y | R | P | A | L | P | R | C | S | L | M | P | A | E |
Template Known Secondary structure |   |
 |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | T | S |
|  |  |  |
| G | G | G | S |
|
| G | G | G | S |
| T | T | G | G | G | G | S |
|
|  |  |  |  |  |  | T | T |
|
| B |
| T | T |
|
|
| S | S |
| G | G | G |
|
| T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . |
  |
  |   |
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | |
|
. | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | Q | A | F | S | Q | R | V | E | R | F | I | A | R | L | S | E | F | Q | H | . |
. |
Y | Q | N | I | L | V | V | S | H | Q | G | V | L | S | L | L | I | A | R | L | I | G | M | P | A | E | A | M | W | H | F | . |
. |
. |
. |
. |
R | V | D | Q | G | C | W | S | A | I | D | I | N | Q | K | F | A | T | L | R | V |
Query Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   | . | . |   |   |   |
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|   |   |
|   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
Template Sequence |   |
S | Y | D | Q | Y | V | E | R | C | A | V | S | M | G | Q | I | I | N | T | C | P | Q | D | M | G | I | T | L | I | V | S | H | S | S | A | L | D | S | C | T | R | P | L | L | G | L | P | P | R | E | C | G | D | F | A | Q | L | V | R | K | I | P | S | L | G | M | C | F | C | E | E | N | R | E | D | G | K | W | D | L |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S | S | S |
|
| S |  |  |  |  |  |  |
| T | T |  |  |  |  | T | T |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |  |  |  | T | T |
|
| T | T |
|  |  |  |  |  |  |
| T | T | T |
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . |
  |
  |   |
193 | . | . |
Predicted Secondary structure |   |
 |
|
|
Query SS confidence |   |
|
|
|
Query Sequence |   |
L | N | S |
Query Conservation |   |
  |
|   |
Alig confidence |   |
|
|
|
Template Conservation |   |
|   |   |
Template Sequence |   |
V | N | P |
Template Known Secondary structure |   |
 |
|
|
Template Predicted Secondary structure |   |
 |
|
|
Template SS confidence |   |
|
|
|
  |   |
600 | . | . |
  |