Job Description P0AAI5 Confidence 100.00% Date Thu Jan 5 11:13:01 GMT 2012 Rank 12 Aligned Residues 394 % Identity 23% Template c3hhdC_ PDB info PDB header:transferase, hydrolase Chain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design. Resolution 2.15 Å

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		2	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.		40	.	.	.	.	.	.	.		.	.	50	.	.	.	.	.	.				.	.	.		60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.
Predicted Secondary structure																																								.									.										.	.	.				.
Query SS confidence																																								.									.										.	.	.				.
Query Sequence		S	K	R	R	V	V	V	T	G	L	G	M	L	S	P	V	G	N	T	V	E	S	T	W	K	A	L	L	A	G	Q	S	G	I	S	L	I	D	.	H	F	D	T	S	A	Y	A	.	T	K	F	A	G	L	V	K	D	.	.	.	F	N	C	.	E	D	I	I	S	R	K	E	Q	R	K	M	D	A	F	I
Query Conservation																																								.									.										.	.	.				.
Alig confidence																																								.									.										.	.	.				.
Template Conservation
Template Sequence		T	G	E	E	V	V	I	A	G	M	S	G	K	L	P	E	S	E	N	L	Q	E	F	W	D	N	L	I	G	G	V	D	M	V	T	D	D	D	R	R	W	K	A	G	L	Y	G	L	P	R	R	S	G	K	L	K	D	L	S	R	F	D	A	S	F	F	G	V	H	P	K	Q	A	H	T	M	D	P	Q	L
Template Known Secondary structure			S												B	T	T	B	S	S										T	T							S	S	S	S	S		T	T	G	G	G			S						S		S					T	T	T	T	T								T	S
Template Predicted Secondary structure
Template SS confidence
		0	.	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.
		76	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	Y	G	I	V	A	G	V	Q	A	M	Q	D	S	G	L	E	I	T	E	E	N	A	T	R	I	G	A	A	I	G	S	G	I	G	G	L	G	L	I	E	E	N	H	T	S	L	M	N	G	G	P	R	K	I	S	P	F	F	V	P	S	T	I	V	N	M	V	A	G	H	L	T	I	M	Y	G	L	R	G
Query Conservation
Alig confidence																																					.	.	.	.	.	.	.
Template Conservation																																					.	.	.	.	.	.	.
Template Sequence		R	L	L	L	E	V	T	Y	E	A	I	V	D	G	G	I	N	P	D	S	L	R	G	T	H	T	G	V	W	V	G	V	S	G	S	.	.	.	.	.	.	.	E	T	S	E	A	L	S	R	D	P	E	T	L	V	G	Y	S	M	V	G	C	Q	R	A	M	M	A	N	R	L	S	F	F	F	D	F	R	G
Template Known Secondary structure															T	T			G	G	G	G	T	T	S												.	.	.	.	.	.	.							T	S		T	T	T			T							S	T	T											T			S
Template Predicted Secondary structure																																					.	.	.	.	.	.	.
Template SS confidence
		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.								.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.
		156	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	S	I	S	I	A	T	A	C	T	S	G	V	H	N	I	G	H	A	A	R	I	I	A	Y	G	D	A	D	V	M	V	A	G	G	A	E	K	A	S	T	P	L	G	V	G	G	F	G	A	A	R	A	L	S	T	R	N	D	N	P	Q	A	A	S	R	P	W	D	K	E	R	D	G	F	V	L	G	D	G
Query Conservation
Alig confidence																																																										.	.	.	.	.
Template Conservation																																																										.	.	.	.	.
Template Sequence		P	S	I	A	L	D	T	A	C	S	S	S	L	M	A	L	Q	N	A	Y	Q	A	I	H	S	G	Q	C	P	A	A	I	V	G	G	I	N	V	L	L	K	P	N	T	S	V	Q	F	L	R	L	G	M	L	S	P	.	.	.	.	.	E	G	T	C	K	A	F	D	T	A	G	N	G	Y	C	R	S	E	G
Template Known Secondary structure									G	G	G															T	T	S		S																							T		B		T	.	.	.	.	.	T	S				T	T	B	T	T				B		B	B
Template Predicted Secondary structure																																																										.	.	.	.	.
Template SS confidence
		153	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.						.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.
		236	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.		.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.
Predicted Secondary structure																																		.
Query SS confidence																																		.
Query Sequence		A	G	M	L	V	L	E	E	Y	E	H	A	K	K	R	G	A	K	I	Y	A	E	L	V	G	F	G	M	S	S	D	A	.	Y	H	M	T	S	P	P	E	N	G	A	G	A	A	L	A	M	A	N	A	L	R	D	A	G	I	E	A	S	Q	I	G	Y	V	N	A	H	G	T	S	T	P	A	G	D	K	A
Query Conservation																																		.
Alig confidence														.	.	.	.																	.
Template Conservation														.	.	.	.
Template Sequence		V	V	A	V	L	L	T	K	K	S	L	A	.	.	.	.	R	R	V	Y	A	T	I	L	N	A	G	T	N	T	D	G	F	K	E	Q	G	V	T	F	P	S	G	D	I	Q	E	Q	L	I	R	S	L	Y	Q	S	A	G	V	A	P	E	S	F	E	Y	I	E	A	H	G	T	G	T	K	V	G	D	P	Q
Template Known Secondary structure										G	G	G		.	.	.	.	S	S		S															T	T		T	T	S																		T			G	G	G												T	T
Template Predicted Secondary structure														.	.	.	.
Template SS confidence
		228	.	230	.	.	.	.	.	.	.	.	.					240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.
		315	.	.	.	.	320	.	.	.	.	.	.	.	.	.		330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380						.	.	.	.	.	.	.	.
Predicted Secondary structure																	.																																																				.	.	.	.	.
Query SS confidence																	.																																																				.	.	.	.	.
Query Sequence		E	A	Q	A	V	K	T	I	F	G	E	A	A	S	R	.	V	L	V	S	S	T	K	S	M	T	G	H	L	L	G	A	A	G	A	V	E	S	I	Y	S	I	L	A	L	R	D	Q	A	V	P	P	T	I	N	L	D	N	P	D	E	G	C	D	L	D	F	.	.	.	.	.	V	P	H	E	A	R	Q	V
Query Conservation																	.																																																				.	.	.	.	.
Alig confidence																	.																																																				.	.	.	.	.
Template Conservation
Template Sequence		E	L	N	G	I	T	R	A	L	C	A	T	R	Q	E	P	L	L	I	G	S	T	K	S	N	M	G	H	P	E	P	A	S	G	L	A	A	L	A	K	V	L	L	S	L	E	H	G	L	W	A	P	N	L	H	F	H	S	P	N	P	E	I	P	A	L	L	D	G	R	L	Q	V	V	D	Q	P	L	P	V
Template Known Secondary structure											S	S	S		S	S							T						B		G	G	G																T	B					S	S			S	B		T	T							T	S						S			B
Template Predicted Secondary structure
Template SS confidence
		304	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.
		389	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	G	M	E	Y	T	L	C	N	S	F	G	F	G	G	T	N	G	S	L	I	F	K	K
Query Conservation
Alig confidence			.
Template Conservation			.
Template Sequence		R	.	G	G	N	V	G	I	N	S	F	G	F	G	G	S	N	V	H	I	I	L	R	P
Template Known Secondary structure			.	S										T	T	S
Template Predicted Secondary structure			.
Template SS confidence
		384		.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.	.