|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | |
. | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | |
|
40 | |
|
|
. | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | |
. | . | . | |
60 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
| . | . |
| . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |
|
|
| . |
|
|
| . |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
| . |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
| . |
|
|
| . |
|
|
Query Sequence |   |
K | R | R | V | V | V | T | G | L | G | M | L | S | P | V | G | . |
N | T | V | E | S | T | W | K | A | L | L | A | G | Q | S | G | I | S | L | I | D | . |
. |
H | . |
. |
. |
F | D | T | S | A | Y | A | T | K | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | G | L | V | K | D | . |
F | N | C | . |
E | D |
Query Conservation |   |
  |   |   |
|
|
|
|
|   |
|   |
|   |
|   |
| . |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   | . | . |   | . | . | . |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   | . |   |
|   | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
| . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . |
|
|
| . |
|
|
Template Conservation |   |
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |
|   |   |
|   |
|
|   |   |
|   |
|   |
|   |   |   |
|   |
|
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|
|
|   |   |
|
Template Sequence |   |
K | Q | L | L | Q | E | V | V | I | E | Q | D | L | E | P | F | E | A | S | K | E | Q | A | E | E | F | K | R | E | H | G | D | K | V | E | I | F | E | I | P | E | T | G | Q | Y | T | V | R | L | R | K | G | A | T | L | L | I | P | K | A | L | Q | F | D | R | L | V | A | G | Q | I | P | T | G | W | D | A | R | R | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| S |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |
| T | T | T | S |
|  |  |  |  |  |
| T | T |
|  |  |  |  |  |  |  |  |
|
| S |
|
|  |  |  |  |
|
| T | T |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1094 | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . |
  |
  |   |
62 | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | |
|
|
|
|
. | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . | . | . | . |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | I | S | R | K | E | Q | R | K | M | D | A | F | I | Q | Y | G | I | V | A | G | V | Q | A | M | Q | D | S | G | L | E | . |
. |
. |
. |
. |
I | T | E | E | N | A | T | R | I | G | A | A | I | G | S | G | I | G | G | L | G | L | I | E | E | N | H | T | S | L | M | N | G | G | P | R | K | I | S | P | F | F | V | P |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|   |
|
|   |   |
|
|   |
|
|
|   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |
|
|
|   |
|
|   |
|   |   |   |   |   |   |   |
|   |
|
|   |   |   |
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |
|   |
Template Sequence |   |
G | V | P | E | D | I | I | Q | Q | V | D | P | V | T | L | Y | V | L | V | S | V | A | E | A | L | L | S | S | G | I | T | D | P | Y | E | F | Y | K | Y | V | H | L | S | E | V | G | N | C | I | G | S | G | V | G | G | T | S | A | L | R | G | M | Y | K | D | R | Y | L | D | . |
. |
K | P | V | Q | K | D | I | L | Q |
Template Known Secondary structure |   |
T |
|
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
| S | S | G | G | G |  |  |  |  | S |
| G | G | G |  |  |  |  |  |  |  | S | S |
|
|  |  |  |  |  |  |  |  | T | T | T | T | T | T | . | . |
|
|
|
| S |
| T | T | G |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1174 | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | 1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | . | . | . | . | . | 1240 | . | . | |
|
. | . | . | . | . | . | . | 1250 | . |
  |
  |   |
137 | . | . | 140 | . | . | . | . | . | . | . | . | |
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | |
|
|
|
|
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
S | T | I | V | N | M | V | A | G | H | L | T | . |
I | M | Y | G | L | R | G | P | S | I | S | I | A | T | A | C | T | S | G | V | H | N | I | G | H | A | A | R | I | I | A | Y | G | D | A | D | V | M | V | A | G | G | A | E | K | A | S | T | P | L | G | V | G | G | F | G | A | A | R | A | L | S | . |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |
|
| . |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |
|
|
|   |
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |
|   |
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
| . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|   |   |
|
|   |
|   |   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |
|   |
|
|   |   |   | . |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |
|   |   |   |   |   |
Template Sequence |   |
E | S | F | V | N | T | M | A | A | W | V | N | M | L | L | L | S | S | T | G | P | I | K | T | P | V | G | A | C | A | T | A | V | E | S | L | D | V | G | Y | D | T | I | M | Q | G | K | A | R | V | C | L | V | G | G | F | D | D | . |
F | Q | E | E | G | S | Y | E | F | A | N | M | G | A | T | S | N | A | K | E | E |
Template Known Secondary structure |   |
G | G | S |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|
| B |
|
|
|
|
| G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S |
| S |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |  |  |  |  | T |
| B |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
| . |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1252 | . | . | . | . | . | . | . | 1260 | . | . | . | . | . | . | . | . | . | 1270 | . | . | . | . | . | . | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | . | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . | . | |
1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . | . | . | . | . | . | 1330 |
  |
  |   |
|
211 | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
T | R | N | D | N | P | Q | A | A | S | R | P | W | D | K | E | R | D | G | F | V | L | G | D | G | A | G | M | L | V | L | E | E | Y | E | H | A | K | K | R | G | A | K | I | Y | A | E | L | V | G | F | G | M | S | S | D | A | Y | H | M | T | S | P | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |
|   |   |
|   |   |   |
|
|
|
|   |   |   |
|   |
|
|
|   |   |
|
|   |
|   |   |
|
|   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | A | R | G | R | E | P | G | E | M | S | R | P | T | S | T | T | R | N | G | F | M | E | S | Q | G | C | G | V | Q | V | I | M | T | A | Q | L | A | L | E | M | G | V | P | I | Y | G | I | V | A | M | T | S | T | A | T | D | K | I | G | R | S | V | P | A | P | G | Q | G | V | L | T | T | A | R | E | K | S | G | N |
Template Known Secondary structure |   |
 | T | T | T |
|
| T | T | S | S |
|
| S | S | B | T | T |
|
|
| B |
| B | B |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
| S |
| S |
| S | S |
|
|
| S |
| G | G | G | G | G |
|
|
|
|
| S |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1331 | . | . | . | . | . | . | . | . | 1340 | . | . | . | . | . | . | . | . | . | 1350 | . | . | . | . | . | . | . | . | . | 1360 | . | . | . | . | . | . | . | . | . | 1370 | . | . | . | . | . | . | . | . | . | 1380 | . | . | . | . | . | . | . | . | . | 1390 | . | . | . | . | . | . | . | . | . | 1400 | . | . | . | . | . | . | . | . | . | 1410 |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | P | S | P | L | L | D | I | K | Y | R | R | R | Q | L | E | L | R | R | Q | Q | I | K | Q | W | K | E | S | E | Y | L | Y | L | Q | E | E | V | A | A | I | K | S | Q | R | S | E | E | D | G | P | F | D | E | T | A | Y | L | R | E | R | T | E | H | I | E | R | E | A | R | R | Q | E | A | E | A | Q | T | S | F | G |
Template Known Secondary structure |   |
S |
|
| G | G | G | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |
|
| S | S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1411 | . | . | . | . | . | . | . | . | 1420 | . | . | . | . | . | . | . | . | . | 1430 | . | . | . | . | . | . | . | . | . | 1440 | . | . | . | . | . | . | . | . | . | 1450 | . | . | . | . | . | . | . | . | . | 1460 | . | . | . | . | . | . | . | . | . | 1470 | . | . | . | . | . | . | . | . | . | 1480 | . | . | . | . | . | . | . | . | . | 1490 |
  |
  |   |
|
|
|
|
276 | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | |
|
|
|
. | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
N | G | A | G | A | A | L | A | M | A | N | A | L | R | D | A | G | I | E | A | S | Q | I | G | Y | V | N | A | H | G | T | S | T | P | A | G | D | K | A | E | A | Q | A | V | K | T | I | F | G | E | . |
. |
. |
. |
A | A | S | R | V | L | V | S | S | T | K | S | M | T | G | H | L | L | G | A | A | G |
Query Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|
|   |   |   |   |
|
|   |
|   |   |
|
|
|
|
|   |   |   |
|   |   |
|   |   |
|
|   |   |
|
|   |   | . | . | . | . |   |   |   |   |   |   |
|   |
|   |
|   |   |   |
|
|   |   |   |
|
|
|
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|
|   |   |
|
|   |   |   |
|
|   |   |
|   |   |
|
|
|   |
|   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |
|
|
|
Template Sequence |   |
N | E | F | W | R | R | D | S | R | I | A | P | L | R | G | A | L | A | T | W | G | L | T | I | D | D | L | G | V | A | S | F | H | G | T | S | T | V | A | N | D | K | N | E | S | D | V | I | C | Q | Q | L | K | H | L | G | R | T | K | G | N | A | V | L | G | I | F | Q | K | Y | L | T | G | H | P | K | G | A | A | G |
Template Known Secondary structure |   |
T | S | T | T | T | T |
| T | T | S |
|  |  |  |  |  |  |  | T | T | T |
|
| G | G | G |  |  |  |  |  |
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|
|  |  |  |  |
| T |  |  |  |  |
| B |
| S | S |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1491 | . | . | . | . | . | . | . | . | 1500 | . | . | . | . | . | . | . | . | . | 1510 | . | . | . | . | . | . | . | . | . | 1520 | . | . | . | . | . | . | . | . | . | 1530 | . | . | . | . | . | . | . | . | . | 1540 | . | . | . | . | . | . | . | . | . | 1550 | . | . | . | . | . | . | . | . | . | 1560 | . | . | . | . | . | . | . | . | . | 1570 |
  |
  |   |
348 | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | |
|
|
. | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | V | E | S | I | Y | S | I | L | A | L | R | D | Q | A | V | P | P | T | I | N | L | D | N | P | D | E | G | C | D | L | . |
. |
. |
D | F | V | P | H | E | A | R | Q | V | S | G | M | E | Y | T | L | C | N | S | F | G | F | G | G | T | N | G | S | L | I | F | K |
Query Conservation |   |
  |   |   |
|   |   |
|   |
|   |
|   |   |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |
|   |
|
|   |
|   |   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |   |   |   |
|   |   |
|   |
|
|   |
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |
|   |   |
Template Sequence |   |
A | W | M | L | N | G | C | L | Q | V | L | N | T | G | I | V | P | G | N | R | N | A | D | N | V | D | K | V | M | E | Q | F | D | Y | I | V | Y | P | S | R | S | I | K | T | D | G | I | K | A | F | S | V | T | S | F | G | F | G | Q | K | G | A | Q | A | I | G | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |
|
|
| T | T |
|
| S | B |
| G | G | G | G | G |
| T | T |  |  |
|
| S | S |
|  |  |
| S |
|
|
|  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1571 | . | . | . | . | . | . | . | . | 1580 | . | . | . | . | . | . | . | . | . | 1590 | . | . | . | . | . | . | . | . | . | 1600 | . | . | . | . | . | . | . | . | . | 1610 | . | . | . | . | . | . | . | . | . | 1620 | . | . | . | . | . | . | . | . | . | 1630 | . | . | . | . | . | . | . |
  |