|   |
11 | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
N | D | L | S | I | D | L | G | T | A | N | T | L | I | Y | V | K | G | Q | G | I | V | L | N | E | P | S | V | V | A | I | R | Q | D | R | A | G | S | P | K | S | V | A | A | V | G | H | D | A | K | Q | M | L | G | R | T | P | G | N | I | A | A | I | R | P | M | K | D | G | V | I | A | D | F | F | V | . |
. |
. |
. |
Query Conservation |   |
  |   |
|
|
|
|   |
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
  |
|
|
|
|   |
|
|   |   |
|   |
|   |
|
|
|   |
|
|   |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|
Template Sequence |   |
I | V | L | G | L | E | G | T | A | H | T | I | S | C | G | I | I | D | E | S | R | I | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
M | E | S | S | M | Y | R | P | K | T | G | G | I | R | P | L | D | A | A | V | H | H |
Template Known Secondary structure |   |
|  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |
| S | S |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
| T | T |
| S |
|
|  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . |
  |
  |   |
87 | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | |
|
. | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | E | K | M | L | Q | H | F | I | K | Q | V | H | S | N | S | F | M | R | P | S | P | R | V | L | V | C | V | . |
. |
P | V | G | A | T | Q | V | E | R | R | A | I | R | E | S | A | Q | G | A | G | A | R | E | V | F | L | I | E | E | P | M | A | A | A | I | G | A | G | L | P | V | S | E | A | T | G | S | M | V | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |
|
|
|   |
|
|   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|
|
Template Sequence |   |
S | E | V | I | D | T | V | I | S | R | A | L | E | K | A | K | I | S | I | H | D | I | D | L | I | G | F | S | M | G | P | G | L | A | P | S | L | R | V | T | A | T | A | A | R | T | I | S | V | L | T | G | K | P | I | I | G | V | N | H | P | L | G | H | I | E | I | G | R | R | V | T | G | A | I | D | P | V | M | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G |
|
|  |  |  |  |  |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S | S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
48 | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . |
  |
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
. | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | G | G | G | T | T | E | V | A | V | I | S | L | N | G | . |
. |
V | V | Y | S | S | S | V | R | I | G | G | D | R | F | D | E | A | I | I | N | Y | V | R | R | N | Y | G | S | L | I | G | E | A | T | A | E | R | I | K | H | E | I | G | S | A | Y | P | G | D | E | V | R | E | I | E | V | R | G | R | N | L | A |
Query Conservation |   |
|   |
|   |   |
|
|   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |
|
|   | . | . | . | . | . |   |
|   |   |
|
|   |   |   |   |   | . | . | . |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | V | S | G | G | N | T | Q | V | I | A | H | V | N | G | R | Y | R | V | L | G | E | T | L | D | I | G | I | G | N | M | I | D | K | . |
. |
. |
. |
. |
F | A | R | E | A | G | I | P | F | P | G | . |
. |
. |
G | P | E | I | E | K | L | A | M | K | G | T | K | L | L | D | L | P | Y | S | V | K | G | M | D | T | A |
Template Known Secondary structure |   |
 |  | S | S | S |
|  |  |  |  |  |  |
| S | S | B |  |  |  |  |  |  | B | S | S |
|
|  |  |  |  |  |  |  | . | . | . | . | . |  |  | T | T | T | T |
|
| S |
|  | . | . | . |  |  |  |  |  | T | T | S | T | T |
|
| S |
|
|
|
|
|
|
|  |  | T | T |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
| . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 170 | . | . | |
|
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . |
  |
  |   |
243 | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
|
|
. | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
E | G | V | P | R | G | F | T | L | N | S | N | E | I | L | E | A | L | Q | E | P | L | T | G | I | V | S | A | V | M | V | A | L | E | Q | C | P | P | E | L | A | S | D | I | S | E | R | G | M | V | L | T | G | G | G | A | L | L | R | N | L | D | R | L | L | M | E | E | T | . |
. |
. |
G | I | P | V | V | V | A | E |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
|   |   |
|   |
|   |   |   |
|   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
F | S | G | I | L | T | A | A | L | Q | Y | L | K | T | G | Q | A | I | E | D | I | S | Y | S | I | Q | E | T | A | F | A | M | L | V | E | V | L | E | R | A | L | Y | V | S | G | K | D | E | I | L | M | A | G | G | V | A | L | N | R | R | L | R | D | M | V | T | N | M | A | R | E | A | G | I | R | S | Y | L | T | D |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  | S | S | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |  |  |
|
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . |
  |
  |   |
320 | . | |
|
|
. | . | . | . | . | . | . | . | 330 | . | . | . | . |
Predicted Secondary structure |   |
|  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | P | . |
. |
. |
L | T | C | V | A | R | G | G | G | K | A | L | E |
Query Conservation |   |
  |
| . | . | . |   |   |
|
|
|   |
|
|
|
|   |
|   |
Alig confidence |   |
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
Template Sequence |   |
R | E | Y | C | M | D | N | G | I | M | I | A | Q | A | A | L | L | M |
Template Known Secondary structure |   |
T | T | T | T | S |
|
| S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |