Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	S	K	F	S	N	F	I	I	N	K	P	F	S	V	I	N	N	A	A	C	H	I	F	S	R	Y	L	L	E	N	K	H	L	F	Y	Q	Y	F	K	I	S	N	T	C	I	D	H	L	E	Q	L	I	N	V	N	F	F	S	S
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.
Sequence		D	R	T	S	F	C	E	C	N	R	F	P
Secondary structure
SS confidence
Disorder								?	?	?	?	?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 2rdc chain A Region: 19 - 29 Aligned: 11 Modelled: 11 Confidence: 12.2% Identity: 36% PDB header:lipid binding protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative lipid binding protein (gsu0061) from2 geobacter sulfurreducens pca at 1.80 a resolution Phyre2 PDB 2ivx chain A domain 1 Region: 19 - 46 Aligned: 28 Modelled: 28 Confidence: 9.0% Identity: 18% Fold: Cyclin-like Superfamily: Cyclin-like Family: Cyclin Phyre2 PDB 1j73 chain A Region: 16 - 31 Aligned: 16 Modelled: 16 Confidence: 8.2% Identity: 50% PDB header:hormone/growth factor Chain: A: PDB Molecule:insulin a; PDBTitle: crystal structure of an unstable insulin analog with native activity. Phyre2 PDB 1j73 chain C Region: 16 - 31 Aligned: 16 Modelled: 16 Confidence: 8.2% Identity: 50% PDB header:hormone/growth factor Chain: C: PDB Molecule:insulin a; PDBTitle: crystal structure of an unstable insulin analog with native activity. Phyre2 PDB 3fq9 chain A Region: 16 - 31 Aligned: 16 Modelled: 16 Confidence: 7.5% Identity: 50% PDB header:hormone Chain: A: PDB Molecule:insulin; PDBTitle: design of an insulin analog with enhanced receptor-binding2 selectivity. rationale, structure, and therapeutic3 implications Phyre2 PDB 3fq9 chain C Region: 16 - 31 Aligned: 16 Modelled: 16 Confidence: 7.5% Identity: 50% PDB header:hormone Chain: C: PDB Molecule:insulin; PDBTitle: design of an insulin analog with enhanced receptor-binding2 selectivity. rationale, structure, and therapeutic3 implications Phyre2 PDB 3lem chain A Region: 33 - 38 Aligned: 6 Modelled: 6 Confidence: 7.2% Identity: 17% PDB header:hydrolase Chain: A: PDB Molecule:fructosyltransferase; PDBTitle: crystal structure of fructosyltransferase (d191a) from a. japonicus in2 complex with nystose Phyre2 PDB 3kf5 chain A Region: 33 - 38 Aligned: 6 Modelled: 6 Confidence: 6.2% Identity: 67% PDB header:hydrolase Chain: A: PDB Molecule:invertase; PDBTitle: structure of invertase from schwanniomyces occidentalis Phyre2 PDB 3ugf chain B Region: 33 - 38 Aligned: 6 Modelled: 6 Confidence: 5.7% Identity: 83% PDB header:transferase Chain: B: PDB Molecule:sucrose:(sucrose/fructan) 6-fructosyltransferase; PDBTitle: crystal structure of a 6-sst/6-sft from pachysandra terminalis Phyre2 PDB 3pij chain A Region: 33 - 38 Aligned: 6 Modelled: 6 Confidence: 5.4% Identity: 67% PDB header:hydrolase Chain: A: PDB Molecule:beta-fructofuranosidase; PDBTitle: beta-fructofuranosidase from bifidobacterium longum - complex with2 fructose Phyre2 PDB 3qz3 chain A Region: 39 - 60 Aligned: 22 Modelled: 22 Confidence: 5.1% Identity: 45% PDB header:oxidoreductase Chain: A: PDB Molecule:ferritin; PDBTitle: the crystal structure of ferritin from vibrio cholerae o1 biovar el2 tor str. n16961 Phyre2 1 c2rdcA_ 2 d2ivxa1 3 c1j73A_ 4 c1j73C_ 5 c3fq9A_ 6 c3fq9C_ 7 c3lemA_ 8 c3kf5A_ 9 c3ugfB_ 10 c3pijA_ 11 c3qz3A_

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 c2rdcA_ 12.2 36 PDB header:lipid binding protein Chain: A: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of a putative lipid binding protein (gsu0061) from2 geobacter sulfurreducens pca at 1.80 a resolution 2 d2ivxa1 9.0 18 Fold:Cyclin-like Superfamily:Cyclin-like Family:Cyclin 3 c1j73A_ 8.2 50 PDB header:hormone/growth factor Chain: A: PDB Molecule:insulin a; PDBTitle: crystal structure of an unstable insulin analog with native activity. 4 c1j73C_ 8.2 50 PDB header:hormone/growth factor Chain: C: PDB Molecule:insulin a; PDBTitle: crystal structure of an unstable insulin analog with native activity. 5 c3fq9A_ 7.5 50 PDB header:hormone Chain: A: PDB Molecule:insulin; PDBTitle: design of an insulin analog with enhanced receptor-binding2 selectivity. rationale, structure, and therapeutic3 implications 6 c3fq9C_ 7.5 50 PDB header:hormone Chain: C: PDB Molecule:insulin; PDBTitle: design of an insulin analog with enhanced receptor-binding2 selectivity. rationale, structure, and therapeutic3 implications 7 c3lemA_ 7.2 17 PDB header:hydrolase Chain: A: PDB Molecule:fructosyltransferase; PDBTitle: crystal structure of fructosyltransferase (d191a) from a. japonicus in2 complex with nystose 8 c3kf5A_ 6.2 67 PDB header:hydrolase Chain: A: PDB Molecule:invertase; PDBTitle: structure of invertase from schwanniomyces occidentalis 9 c3ugfB_ 5.7 83 PDB header:transferase Chain: B: PDB Molecule:sucrose:(sucrose/fructan) 6-fructosyltransferase; PDBTitle: crystal structure of a 6-sst/6-sft from pachysandra terminalis 10 c3pijA_ 5.4 67 PDB header:hydrolase Chain: A: PDB Molecule:beta-fructofuranosidase; PDBTitle: beta-fructofuranosidase from bifidobacterium longum - complex with2 fructose 11 c3qz3A_ 5.1 45 PDB header:oxidoreductase Chain: A: PDB Molecule:ferritin; PDBTitle: the crystal structure of ferritin from vibrio cholerae o1 biovar el2 tor str. n16961

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0