|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | |
|
|
|
|
. | . | 20 | . | . | . | . | . | . | . | . | |
|
. | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | D | W | V | T | G | K | V | T | K | V | Q | N | W | T | D | . |
. |
. |
. |
. |
A | L | F | S | L | T | V | H | A | P | V | . |
. |
L | P | F | T | A | G | Q | F | T | K | L | G | L | E | I | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |
|   |
|   |   |
|   |   |   |
|   | . | . | . | . | . |   |   |   |   |
|   |
|   |   |
|   | . | . |   |   |   |   |
|
|
|   |
|   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |   |   |
|   |   |
|
|   |
|   |
|   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | P | V | F | Q | V | P | I | S | K | A | V | Q | L | T | T | N | D | A | I | K | T | T | L | L | V | E | L | D | I | S | N | T | D | F | S | Y | Q | P | G | D | A | F | S | V | I | C | P | N | S | D | S | E | V | Q | S | L | L | Q | R | L | Q | L | E | D | K | R | E | H | V | L | L | K | I | K | A | D | T | K | K |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |
| S |
| T | T |
| S | S |
|  |  |  |  |  |  |  |
| T | T | S |
|
|
|
|
| T | T |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G | T | T |
|
|  |  |  |  |
| T | T |
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
257 | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|
|
|
|
|   |   |
|
|
Template Sequence |   |
K | G | A | T | L | P | Q | H | I | P | A | G | C | S | L | Q | F | I | F | T | W | C | L | E | I | R | A | I | P | K | K | A | F | L | R | A | L | V | D | Y | T | S | D | S | A | E | K | R | R | L | Q | E | L | C | S | K | Q | G | A | A | D | Y | S | R | F | V | R | D | A | A | C | L | L | D | L | L | L | A | F | P |
Template Known Secondary structure |   |
T | T |
|
|
|
| T | T | S |
| T | T |
|
|  |  |  |  |  |  |  | T | B |
| T | T | S |
|
|
|  |  |  |  |  |  |  |  | T | T | B |
| S |  |  |  |  |  |  |  |  |  |  |  | S | S | T | T |  |  |  |  |  |  |  | T | T |
|
|
|
|  |  |  |  |  |  |  | S | T |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
352 | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
45 | . | . | . | . | 50 | . | . | . | . | . | . | . | . | |
|
. | 60 | . | . | . | . | . | . | . | . | . | 70 | . | |
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 80 | . | . | . | . | . | |
|
|
. | . | . | . | 90 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |
|
|
|  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | E | R | V | Q | R | A | Y | S | Y | V | N | S | P | . |
. |
D | N | P | D | L | E | F | Y | L | V | T | V | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | G | K | L | S | P | R | L | A | A | L | K | P | G | . |
. |
. |
D | E | V | Q | V | V | S | E | A | A |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |
|   |   |
|
|   |
|   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|
|   |   |
|
|   |   |
|
|   |
|   |
|
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
Template Sequence |   |
S | C | Q | P | P | L | S | L | L | L | E | H | L | P | K | L | Q | P | R | P | Y | S | C | A | S | S | S | L | F | H | P | G | K | L | H | F | V | F | N | I | V | E | F | L | S | T | A | T | T | E | V | L | R | K | G | V | C | T | G | W | L | A | L | L | V | A | S | V | L | A | P | K | I | S | I | F | P | R | T | T |
Template Known Secondary structure |   |
T | B |
|
|
|  |  |  |  |  |  |  |
|
| B |
|
|
|  |  |  |  |
|
| S |
| T | T | T | S | T | T |  |  |  |  |  |  |  |
|
|  |  |  |
| S |
| S | S |
| S |  |  |  |
|  |  |  |  |  |  |  |  |  | G | G | G | T |
|
|
|  |  |  |  |  |  |
| S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
433 | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . |
  |
  |   |
96 | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | |
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  | . |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | F | F | V | L | D | E | V | P | H | C | E | T | L | W | M | L | A | T | G | T | A | I | G | P | Y | L | S | I | L | Q | L | G | K | D | . |
. |
. |
. |
. |
. |
L | D | R | F | K | N | L | V | L | V | H | A | A | R | Y | A | A | D | . |
L | S | Y | L | P | L | M | Q | E | L | E | K | R | Y | E | G | K | L | R | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|
|   |
|   |   |
|   |   |   |   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|   |   |   |   |
|   |   |   |   | . |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |
| . |
|   |   |   |   |   |
|
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|
|   |
|   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   | . |
|   |   |   |   |
|
Template Sequence |   |
N | S | F | H | L | . |
P | D | D | P | S | I | P | I | I | M | V | G | P | G | T | G | I | A | P | F | I | G | F | L | Q | H | R | E | K | L | Q | E | Q | H | P | D | G | N | F | G | A | M | W | L | F | F | G | C | R | H | K | D | R | D | Y | L | F | R | K | E | L | R | H | F | L | K | H | . |
G | I | L | T | H | L |
Template Known Secondary structure |   |
|
|
|
|
| . |
| S | S | T | T | S |
|  |  |  |  |
|
| G | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | T | T |
|
|
|
|
|  |  |  |  |  |  |  | S |
| T | T | T |
|
| T | T |  |  |  |  |  |  |  |  |  | T | . | T | S | S |
|  |  |
Template Predicted Secondary structure |   |
|
|
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
528 | . | 530 | . | . | |
. | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | |
600 | . | . | . | . | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
. | . | . | . | . | 220 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
| . |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | T | V | V | S | R | E | T | A | A | G | S | L | T | G | R | I | P | A | L | I | E | S | G | E | L | E | S | T | I | G | L | P | M | N | K | E | T | S | H | V | M | L | C | G | N | . |
P | Q | M | V | R | D | T | Q | Q | L | L | K | E |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
| . |   |   |
|   |   |   |
|   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|
|
|
|   |   |   |
|   | . | . | . |
|
|
|
|   |
|   |   |   | . | . |   |   |   |
|   |   |   |
|   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
K | V | S | F | S | R | D | A | P | P | A | K | . |
. |
. |
Y | V | Q | D | N | I | Q | L | H | . |
. |
G | Q | Q | V | A | R | I | L | L | Q | E | N | G | H | I | Y | V | C | G | D | A | K | N | M | A | K | D | V | H | D | A | L | V | Q |
Template Known Secondary structure |   |
 |  |  |  | S | S |
|
|
|
|
|
| . | . | . | S |  |  |  |  |  |  |  | T | . | . |  |  |  |  |  |  |  |  |  |  | S |
|
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
606 | . | . | . | 610 | . | . | . | . | . | . | . | |
|
|
. | . | 620 | . | . | . | . | . | . | |
|
. | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 |
  |