|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
. | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | T | T | L | A | I | D | I | G | G | T | K | L | A | A | A | L | I | G | A | D | G | Q | I | R | D | R | R | E | L | P | T | P | A | S | Q | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | A | L | R | D | A | L | S | A | L | V | S | P | L | Q | A | H | A | Q | R | V | A | I | A | S | T | G | I | I | R | D |
Query Conservation |   |
|   |
|
|
|
|
|   |
|
|
|   |   |   |   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|   |
|
|
|
|   |
|
|   |   |
|   |
|   |
|
|
|   | . |
|
|   |
|
|
|   |
|   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |
|
|
|   |
|
|   |   |   |   |
| . |
Template Sequence |   |
M | I | V | L | G | L | E | G | T | A | H | T | I | S | C | G | I | I | D | . |
E | S | R | I | L | A | M | E | S | S | M | Y | R | P | K | T | G | G | I | R | P | L | D | A | A | V | H | H | S | E | V | I | D | T | V | I | S | R | A | L | E | K | A | K | I | S | I | H | D | I | D | L | I | G | F | S | M | G | P | . |
Template Known Secondary structure |   |
|
|  |  |  |  |  |
| S | S | S |  |  |  |  |  |  |  |
| . | S | S |
|
|
|  |  |  |  |  |  |
|
|
| T | T |
| S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
| G | G | G |
|
|  |  |  |  |  |
| S | S | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  | . |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|  |  |  |  |  |
|
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | |
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | |
  |
  |   |
70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | |
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
Query Sequence |   |
G | S | L | L | A | L | N | P | H | N | L | G | G | L | L | H | F | P | L | V | K | T | L | E | Q | L | T | N | L | P | T | I | A | I | N | D | A | Q | A | A | A | W | A | E | F | Q | A | L | D | G | D | I | T | D | M | V | F | I | T | V | S | T | G | V | G | G | G | V | V | S | G | C | K | L | L | T | . |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
Template Conservation |   |
. | . | . | . | . | . | . |
|   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|
|   |
|
|   |   |   |
| . | . |   |   |   |   |   |   |
|
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
G | L | A | P | S | L | R | V | T | A | T | A | A | R | T | I | S | V | L | T | G | K | P | I | I | G | V | N | H | P | L | G | H | I | E | I | G | R | R | V | T | . |
. |
G | A | I | D | P | V | M | L | Y | V | S | G | G | N | T | Q | V | I | A | H | V | N | G | R | Y | R | V | L | G | E |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T |
| S | S |
|  |  |  |  |  | S | S | S |
|  |  |  |  |  |  |
| S | S | B |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | |
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | P | G | G | L | A | G | H | I | G | H | T | L | A | D | P | H | G | P | V | C | G | C | G | R | T | G | C | V | E | A | I | A | S | G | R | G | I | A | A | A | A | Q | G | E | L | A | G | A | D | A | K | T | I | F | T | R | A | G | Q | G | D | E |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |
|
|   |   |
|   |   |
|
|   | . |   |   |   |   |   |   |
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . |
|
Template Sequence |   |
T | L | D | I | G | I | G | N | M | I | D | K | F | A | R | E | A | G | I | . |
P | F | P | G | G | P | E | I | E | K | L | A | M | K | G | T | K | L | L | D | L | P | Y | S | V | K | G | M | D | T | A | F | S | G | I | L | T | A | A | L | Q | Y | L | K | T | G | Q | A | I | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
D |
Template Known Secondary structure |   |
B | S | S |
|
|  |  |  |  |  |  |  |  |  | T | T | T | T |
| . |
| S |
|  |  |  |  |  |  | T | T | S | T | T |
|
| S |
|
|
|
|
|
|
|  |  | T | T |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  | . | . | . | . | . | . | . | . | . |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | |
. | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
. |
  |
  |   |
209 | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | |
. | . | . | . | . | . | 280 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
| . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | A | Q | Q | L | I | H | R | S | A | R | T | L | A | R | L | I | A | D | I | K | A | T | T | D | C | Q | C | V | V | V | G | G | S | V | G | L | A | E | G | Y | L | A | L | V | E | T | Y | L | A | Q | E | P | A | A | F | H | V | D | L | L | A | A | H | Y | . |
R | H | D | A | G | L | L | G | A | A | L | L | A | Q |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |   |   |   |   |   |   |   |
|
|
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|
|
|   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |   |   |   |
Template Sequence |   |
I | S | Y | S | I | Q | E | T | A | F | A | M | L | V | E | V | L | E | R | A | L | Y | V | S | G | K | D | E | I | L | M | A | G | G | V | A | L | N | R | R | L | R | D | M | V | T | N | M | A | R | E | A | . |
. |
G | I | R | S | Y | L | T | D | R | E | Y | C | M | D | N | G | I | M | I | A | Q | A | A | L | L | M |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S |  |  |  |  |  | S | S | G | G | G |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | T | S |  |  |
|
|
|
| T | T | T | T | S |
|
| S |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | |
|
. | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . |
  |
  |   |
288 | . | 290 |
Predicted Secondary structure |   |
|
|
|
Query SS confidence |   |
|
|
|
Query Sequence |   |
G | E | K |
Query Conservation |   |
  |   |   |
Alig confidence |   |
|
|
|
Template Conservation |   |
  |   |   |
Template Sequence |   |
Y | K | S |
Template Known Secondary structure |   |
 |  | T |
Template Predicted Secondary structure |   |
 |  |
|
Template SS confidence |   |
|
|
|
  |   |
298 | . | 300 |
  |