|   |
341 | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
E | K | V | S | F | D | L | W | P | G | E | T | L | S | L | V | G | E | S | G | S | G | K | S | T | T | G | R | A | L | L | R | L | V | E | S | Q | G | G | E | I | I | F | N | G | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | I | D |
Query Conservation |   |
  |   |
|
|   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|
|   |
|   |
|   |   |   |
|   |   |
|   |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | V | T | K | V | G | F | G | E | S | N | F | T | S | I | I | G | P | N | G | S | G | K | S | N | M | M | D | A | I | S | F | V | L | G | V | L | K | D | L | I | Y | R | G | P | Q | S | A | Y | V | K | A | F | Y | Q | K | G | N | K | L | V | E | L | M | R | I | I | S | R | N | G | D | T | S | Y | K | I | D | G | K |
Template Known Secondary structure |   |
S |  |  |  |  |  |
| T | T |
| S |  |  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
| G | G | G | S |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  | T | T | S |
|  |  |  |  |  | T | T |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
17 | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . |
  |
  |   |
390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
Query Sequence |   |
T | L | S | P | G | K | L | Q | A | L | R | R | D | I | Q | F | I | F | Q | D | P | Y | A | S | L | D | P | R | Q | T | I | G | D | S | I | I | E | P | L | R | V | H | G | L | L | P | G | K | D | A | A | A | R | V | A | W | L | L | E | R | V | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | P | E | H | A | W | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|   |
|   |   |   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
| . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
T | V | S | Y | K | D | Y | S | I | F | L | E | N | E | N | I | L | I | K | A | K | N | F | L | V | F | Q | G | D | V | E | Q | I | A | A | Q | S | P | V | E | L | S | R | M | F | T | F | D | Y | V | S | D | H | L | D | A | I | Y | R | E | L | T | G | N | A | S | L | T | K | Y | H | A | T | P | P | L | K | R | F | K |
Template Known Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  | T | T |
|
| T | T | T |
| T | T |  |  |
| T | T |
| T | T |  |  |  |  | S |
|  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
|  |  |  |  |
| T | T |
|
|
|
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
125 | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . |
  |
  |   |
460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | |
|
|
|
. | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | P | H | E | F | S | G | G | Q | R | Q | R | I | C | I | A | R | A | L | . |
. |
. |
. |
A | L | N | P | K | V | I | I | A | D | E | A | V | S | A | L | D | V | S | I | R | G | Q | I | I | N | L | L | L | D | L | Q | R | D | F | G | I | A | Y | L | F | I | S | H | D | M | A | V | V | E | R | I | S | H | R | V | A |
Query Conservation |   |
  |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
| . | . | . | . |   |   |   |
|   |
|
|
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |
|
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|
|   |   |   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . |   |   |
|   |
|   |
|
|
|   |   |   |   |   |   |   | . |   |
|   |   |   |
Template Sequence |   |
D | M | E | Y | L | S | G | G | E | K | T | V | A | A | L | A | L | L | F | A | I | N | S | Y | Q | P | S | P | F | F | V | L | D | E | V | D | A | A | L | D | I | T | N | V | Q | R | I | A | A | Y | I | R | R | H | R | N | P | . |
D | L | Q | F | I | V | I | S | L | K | N | T | M | F | E | K | . |
S | D | A | L | V |
Template Known Secondary structure |   |
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S | S |
|
| S |  |  |  |  | S | S | T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| B | T | . | T | B |  |  |  |  |  |
| S |
|  |  |  |  | T | T | . |
| S |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  | . |
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1125 | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | |
. | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | |
. | . | 1200 | . | . |
  |
  |   |
536 | . | . |
Predicted Secondary structure |   |
 |  |  |
Query SS confidence |   |
|
|
|
Query Sequence |   |
V | M | Y |
Query Conservation |   |
|
|   |
Alig confidence |   |
|
|
|
Template Conservation |   |
  |   |   |
Template Sequence |   |
G | V | Y |
Template Known Secondary structure |   |
 |  |  |
Template Predicted Secondary structure |   |
 |  |  |
Template SS confidence |   |
|
|
|
  |   |
1203 | . | . |
  |