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Job DescriptionP75796
Confidence100.00%DateThu Jan 5 12:14:14 GMT 2012
Rank6Aligned Residues494
% Identity27%Templatec2ygrD_
PDB info PDB header:hydrolaseChain: D: PDB Molecule:uvrabc system protein a; PDBTitle: mycobacterium tuberculosis uvra
Resolution3.40 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   13......20.........30.........40.........50......... 60.........70.
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Query Sequence  LAVENLNIAFMQDQQKIAAVRNLSFSLQRGETLAIVGESGSGKSVTA. . . . . . . . . . . . . . . . . . . . . LALMRLLEQAGG
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Template Conservation 
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Template Sequence  LIVKGAR. . . . . . . . . EHNLRSVDLDLPRDALIVFTGLSGSGKSSLAFDTIFAEGQRRYVESLSAYARQFLGQMDKPDVD
Template Known Secondary structure 
.........SSS

SSSS
STTSSTTTTTT
STTTS




S
Template Predicted Secondary structure 


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   5....10. ........20.........30.........40.........50.........60.........70.....
 
   72.. .....80.........90.........100......
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Query Sequence  LVQ. . . . . . . CDKMLLQRRSREVIELSEQNAAQMRHVRGADM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation   
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Template Sequence  FIEGLSPAVSIDQKSTNRNPRSTVGTITEVYDYLRLLYARAGTPHCPTCGERVARQTPQQIVDQVLAMPEGTRFLVLAPV
Template Known Secondary structure  S



S





TT
BTTSSB
B
TTT

B
B


SS

SS


S
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   76...80.........90.........100.........110.........120.........130.........140.........150.....
 
  
Predicted Secondary structure  ................................................................................
Query SS confidence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation  ................................................................................
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Template Sequence  VRTRKGEFADLFDKLNAQGYSRVRVDGVVHPLTDPPRARRQEKHDIEVVVDKRRLTDSVETALNLADGIVVLEFVDHRFS
Template Known Secondary structure  SSSB
S
TTS

S
BSSS
B
TTS




TTS
B




SSS







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   156...160.........170.........180.........190.........200.........210.........220.........230.....
 
   107..110.........120 ........
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Query Sequence  . . . . . . . . . AMIFQEPMTSLNPV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . FTVGEQIA
Query Conservation  .........  
 
 
   
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Template Conservation                      

 

  
 
  
 
 
     
    
     
   

                     
Template Sequence  EKLACPNGHALAVDDLEPRSFSFNSPYGACPDCSGLGIRKEVDPELVVPDPDRTLAQGAVAPWSNGHTAEYFTRMMAGLG
Template Known Secondary structure  TTBB
TT



S
S


GGGG
TTSTTTBBTTBSSS


SS

SSSSS
S
STT
SSTT
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   253......260.........270.........280.........290.........300.........310.........320.........330..
 
   129130.........140.....
Predicted Secondary structure 



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Query Sequence  ESIRLHQNASREEAMVE. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 
 
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Template Conservation           
       

 
                          
  
               
        
  
 
Template Sequence  EALGFDVDTPPAKARKAILEGADEQVHVRYRNRYGRTRSYYADFEGVLAFLQRKMSQTESEQMKERYEGFMRDVPCPVCA
Template Known Secondary structure  S

SS


T


S





SSS









S
TTTT
TTTT
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   333......340.........350.........360.........370.........380.........390.........400.........410..
 
   146...150.........160.........170..
Predicted Secondary structure  .....................................................









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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . AKRMLDQVRIPEAQTILSRYPHQLSGG
Query Conservation  .....................................................   

   

             



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Template Conservation 
 

   

      
     
 
  
                
     

   
  
   

  
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Template Sequence  GTRLKPEILAVTLKSIAEVCELSIADCADFLNALTLGPREQAIAGQVLKEIRSRLGFLLDVGLEYLS. . LSRAAATLSGG
Template Known Secondary structure  TS
B
T
B

GGG


TT

TTSTT
TTS
..TTSBGGG

Template Predicted Secondary structure 



















..





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   417..420.........430.........440.........450.........460.........470.........480... ......490....
 
   173......180........ .190.........200.........210.........220.........230.........240.. ..
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Query Sequence  MRQRVMIAMALSCRPA. . VLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVM. . . . . . YQ
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Template Sequence  EAQRIRLATQIGSGLVGVLYVLDEPSIGLHQRDNRRLIETLTRLRDL. GNTLIVVEHDEDTI. EHADWIVDIGPGAGEHG
Template Known Secondary structure  TT


S

TTTT

.
B

.T
SSSSSGGG
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   505....510.........520.........530.........540.........550. ........560..... ....570.........580..
 
   245....250.........260.........270.........280.........290.........300.........310.........320....
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Query Sequence  GEAVETGTVEQIFHAPQHPYTRALLAAVPQLGAMKGLDYPRRFPLISLEHPAKQAPPIEQKTVVDGEPVLRVRNLVTRFP
Query Conservation 
 

  
                
                                             
    
   
 
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Template Sequence  GRIVHSGPYDELLRNKDSITGAY. . . . . . . . . . . . . . . . . . . . . . . . . LSGRESIEIPAIRRSVDPRRQLTVVGARE. . .
Template Known Secondary structure 
S

SS
.........................TS





SS




TTS
S...
Template Predicted Secondary structure 



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...
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   583......590.........600..... ....610.........620.........630....
 
   325....330.........340.........350.........360........ .370.........380.........390.........400..
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Query Sequence  LRSGLLNRVTREVHAVEKVSFDLWPGETLSLVGESGSGKSTTGR. . ALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRD
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Template Sequence  . . . . . . . . . . . . . HNLRGIDVSFPLGVLTSVTGVSGSGKSTLVNDILAAVLANRLNGARQVPGRHTRVTGLDY. . . . LDK
Template Known Secondary structure  .............TT

SSSSSTTSSTTS






SS


GGG....


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   635....640.........650.........660.........670.........680.........690.... ...
 
   403......410
Predicted Secondary structure 


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Query Sequence  IQFIFQDP. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation 
  
 
 
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Template Conservation 
  
 
 
      
           

 

                
 
   
      
 
        
        
Template Sequence  LVRIDQSPIGRTPRSNPATYTGVFDKIRTLFAATNEAKVRGYKPGRFSFNVKGGRCEACTGDGTIKIEMNFLPDVYVPCE
Template Known Secondary structure 

S
S
SSTT
STTSTTT

GGGS
TTSTTTB
SSSTTSS

SSS


T
Template Predicted Secondary structure 




























































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   698.700.........710.........720.........730.........740.........750.........760.........770.......
 
   411........420.... .....430.........440.........450.........460.........470........
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Query Sequence  . . . . . . . . . . . YASLDPRQTIGDSI. IEPLRVHGLLPGKDAAARVAWLLERVGLLPEHAWRYPHEFSGGQRQRICIARAL
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Template Sequence  VCQGARYNRETLEVHYKGKTVSEVLDMSIEEAAEFFEPIAGVHRYLRTLVDVGLGYVRLGQPAPTLSGGEAQRVKLASEL
Template Known Secondary structure  TTTS
SB
T

BTTB
TSBSTT
SS
SSSBTT

GGGS
S
Template Predicted Secondary structure 































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   778.780.........790.........800.........810.........820.........830.........840.........850.......
 
   479480. ........490.........500.........510.........520.........530....... ..540.........
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Query Sequence  ALN. . . PKVIIADEAVSALDVSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVM. . . . . . YLGQIVEIGPRR
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Template Sequence  QKRSTGRTVYILDEPTTGLHFDDIRKLLNVINGLVDK. GNTVIVIEHNLDVIKT. SDWIIDLGPEGGAGGGTVVAQGTPE
Template Known Secondary structure  SS


SS
SSSTT

.T



.
SSSSTTS
S
S
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   858.860.........870.........880.........890.... .....900.........910 .........920.........930.....
 
   550.........560.......
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Query Sequence  AVFENPQHPYTRKLLAAV
Query Conservation       
    
  
    
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Template Conservation 

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Template Sequence  DVAAVPAS. YTGKFLAEV
Template Known Secondary structure  TT
SS
.TTT
Template Predicted Secondary structure 



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   936...940... ......950..
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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