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Job DescriptionP77444
Confidence100.00%DateThu Jan 5 12:29:21 GMT 2012
Rank4Aligned Residues374
% Identity16%Templatec3e9kA_
PDB info PDB header:hydrolaseChain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex
Resolution1.70 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   15....20.........30.........40.........50.........60.........70.........80.........90....
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Query Sequence  LSREVNGLPLAYLDSAASAQKPSQVIDAEAEFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGT
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Template Sequence  LSLVNKDENAIYFLGNSLGLQPKMVKTYLEEELDKWAKIAAYGHEVGKRPWITGDESIVGLMKDIVGA. NEKEIALMNAL
Template Known Secondary structure  GGGS
TT
B

BTTTS

B
TTGGGGGTSSSS
GGGTTGGGT
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GGG
S
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   5960.........70.........80.........90.........100.........110.........120...... ...130.......
 
   95....100.........110.........120.........130.........140 .........150.........160. .....
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Query Sequence  TEGINLVANSWGNSNVRAGDNIIISQMEHHANIVPWQMLCARVGAE. . . . . LRVIPLNPDGTLQLETLPTLF. . . DEKTR
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Template Sequence  TVNLHLLMLSFFKPT. PKRYKILLEAKAFPSDHYAIESQLQLHGLNIEESMRMIKPREGEETLRIEDILEVIEKEGDSIA
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.SSS
TT

TT




TT
SS

GGG
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   138.140.........150.. .......160.........170.........180.........190.........200.........210......
 
   167..170.........180.........190.........200.........210.........220........ .230.........240....
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Query Sequence  LLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCDFYVFSGHKLY. . GPTGIGILYVKEALLQ
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Template Sequence  VILFSGVHFYTGQHFNIPAITKAGQAKGCYVGFDLAHAVGNVELYLHDWGVDFACWCSYKYLNAGAGGIAGAFIHEKHAH
Template Known Secondary structure  SB
TTT
BB

TT

TTTTTTS


T


SSSTT


TT



GGGTT
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   217..220.........230.........240.........250.........260.........270.........280.........290......
 
   245....250.........260. ........270.........280.........290.........300.........310....... ..320
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Query Sequence  EMPPWEGGGSMIATVSL. . . SEGTTWTKAPWRFEAGTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALSQL. ESV
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Template Sequence  TIKPALVGWFGHELSTRFKMDNKLQLIPGVCGFRISNPPILLVCSLHASLEIFKQATMKALRKKSVLLTGYLEYLIKHNY
Template Known Secondary structure  TS

SS

GGGB
TT

S


B
SSGGGG

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   297..300.........310.........320.........330.........340.........350.........360.........370......
 
   321........330 .........340.........350.........360.........370.........380.. .......390......
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Query Sequence  PDLTLYGPQN. . . RLGVIAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASL. AMYNTHEEVDRLVT
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Template Sequence  GVVNIITPSHVEERGCQLTITFSV. PNKDVFQELEKRGVVCDK. . . . . . . . . . . . RNPNGIRVAPVPLYNSFHDVYKFTN
Template Known Secondary structure 


S
SSGGGB
S


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TTT
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TTT

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   377..380.........390.........400 .........410........ .420.........430.........440...
 
   397..400...
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Query Sequence  GLQRIHR
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Template Sequence  LLTSILD
Template Known Secondary structure  T
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   453......
 
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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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