|   |
10 | . | . | . | . | |
|
. | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  | . | . |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | P | F | V | K | . |
. |
Q | S | K | D | Q | L | L | I | T | L | W | L | T | G | E | D | P | P | Q | R | I | M | L | R | T | E | H | D | N | E | E | M | S | V | P | M | H | K | Q | R | S | Q | P | Q | P | G | V | T | A | W | R | A | A | I | D | L | S | S | G | Q | P | R | R | R | Y | S | F | K | L | L | W | H | D |
Query Conservation |   |
  |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
Template Conservation |   |
  |   |   |
|
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|   |
|   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . |   |   |   |
|   |
|   |   |   |   |   |   | . | . |   |   |   |
|   |   |
|   |
|   |
| . | . |   |   |
Template Sequence |   |
K | S | W | G | A | E | Y | I | A | A | D | V | V | R | F | R | L | W | A | T | G | Q | Q | K | V | M | L | R | L | . |
. |
. |
. |
. |
. |
. |
A | G | K | D | Q | E | M | Q | A | . |
. |
. |
. |
. |
. |
N | G | D | G | W | F | T | L | D | V | A | G | . |
. |
V | T | P | G | T | E | Y | N | F | V | L | . |
. |
S | D |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
| T | T |
| S |
|  |  |  |  |  | . | . | . | . | . | . | . | T | T |  |  |  |  |
|  |  | . | . | . | . | . | . |
| S | T | T |  |  |  |  |  |  |  | T | . | . |
|
| T | T |
|  |  |  |  |  |  | . | . | T | T |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
| . | . |
|
|
|
|
|  |  |  |  |  |  | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
8 | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 40 | . | . | . | . | . | |
|
|
|
|
|
. | . | . | . | 50 | . | . | . | . | . | . | . | |
|
. | . | 60 | . | . | . | . | . | . | . | . | |
|
. | 70 |
  |
  |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
|
. | |
|
|
|
120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . | . |
| . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | Q | R | W | F | T | P | Q | G | F | S | R | M | P | P | A | R | L | E | Q | F | A | V | D | V | P | D | I | G | P | Q | . |
. |
. |
W | . |
. |
. |
. |
A | A | D | Q | I | F | Y | Q | I | F | P | D | R | F | A | R | S | L | P | R | E | A | E | Q | D | H | V | Y | Y | H | H | A | A | G | Q | E | I | I | L | R | D |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . |
| . | . | . | . |   |   |   |   |
|   |
|   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
G | M | V | V | P | D | P | A | S | R | A | Q | K | T | D | V | N | G | P | S | Y | V | V | D | P | G | S | Y | T | W | R | N | T | G | W | K | G | S | R | W | E | Q | A | V | V | Y | E | M | H | T | G | T | F | T | P | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |
|  |  |
|
| T | T |
| S |
| B | S | S | S | T | T | S |
|  |  |
|
|
| T | T | S | S |
|
| S |
| T | T |
|
|
|
|
| G | G | G |
|
|  |  |  |  |
|  |  |  |  | S | S | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
71 | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |
  |   |
161 | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | |
|
. | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | D | E | P | V | T | A | Q | A | G | G | S | T | F | Y | G | G | D | L | D | G | I | S | E | K | L | P | Y | L | K | K | L | G | V | T | A | L | Y | L | N | P | V | F | K | A | P | S | . |
. |
V | H | K | Y | D | T | E | D | Y | R | H | V | D | P | Q | F | G | G | D | G | A | L | L | R | L | R | H | N | T | Q | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |   |
|
|
|
|
|
|   |
|
|
|   |   |
|   |
|   |
|
|   |   |   |   |   | . | . |   |   |
|
|   |   |   |
|
|   |   |
|
|   |   |   |
|
|   |   |
|
|
|   |
|
|   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |
|   |   |   |
|
|
|
|
|   |   |
|
|
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |
|   |   |
|
|   |   |   |
|
|   |   |
|
|
|   |
|
|   |   |
|
|   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | T | F | R | A | A | I | A | K | L | P | Y | L | A | E | L | G | V | T | V | I | E | V | M | P | V | A | Q | F | G | G | E | R | G | W | G | Y | D | G | V | L | L | Y | A | P | H | S | A | Y | G | T | P | D | D | F | K | A | F | I | D | A | A | H | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
| S |  |  |  |  |  | T | T |  |  |  |  |  |  |  | T |
|
|  |  |  |  |
|
|
|  |  |
| S | S | S |
|
|
| S | T | T |
|
|  |  |  |  |  |
| T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
127 | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 |
  |
  |   |
239 | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | M | R | L | V | L | D | G | V | F | N | H | S | G | D | S | H | A | W | F | D | R | H | N | R | G | T | G | G | A | C | H | N | P | E | S | P | W | R | D | W | Y | S | F | S | D | D | G | T | A | L | D | W | L | G | Y | A | S | L | P | K | L | D | Y | Q | S | E | S | L | V | N | E | I | Y | R | G | E | D | S |
Query Conservation |   |
  |
|
|   |
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |
|
|   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|
|   |
|
|
|   |   |   |   |   |
|
|   |   |
|   |
|   | . | . | . |
Template Sequence |   |
Y | G | L | S | V | V | L | D | I | V | L | N | H | F | G | P | E | G | N | Y | L | P | L | L | A | P | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
F | F | H | K | E | R | . |
. |
. |
. |
. |
. |
. |
. |
M | T | P | W | G | N | G | I | A | Y | D | V | D | A | V | R | R | Y | I | I | E | A | . |
. |
. |
Template Known Secondary structure |   |
T | T |
|  |  |  |  |  |  |
|
| S |
|
|
| S | S | S |
|
|  |  |  |  |
| G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G |  |  |  |  |  | . | . | . | . | . | . | . | . |  |  | T | T |  |  |  |  |
| T | T | S |  |  |  |  |  |  |  |  |  |  | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
191 | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 220 | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
|
|
  |
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | |
|
. | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | |
|
|
|
|
|
. | . | . | 390 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
Query Sequence |   |
I | V | R | H | W | L | K | A | P | W | N | M | D | G | W | R | L | D | V | V | H | M | L | G | E | A | G | G | A | R | N | N | M | Q | H | V | A | G | I | T | E | A | A | K | E | T | Q | P | E | . |
. |
A | Y | I | V | G | E | H | F | G | D | A | R | Q | W | L | Q | A | D | V | . |
. |
. |
. |
. |
. |
E | D | A | A |
Query Conservation |   |
  |   |   |   |
|
|   |
|   |   |
|
|
|
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |   |
|   |   |
Alig confidence |   |
. |
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
Template Conservation |   |
. |   |   |   |
|
|   |
| . |   |
|
|
|
|
|
|   |
|   |   |   |   |
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
P | L | Y | W | L | T | E | . |
Y | H | L | D | G | L | R | F | D | A | I | D | Q | I | E | D | S | S | . |
. |
. |
. |
A | R | H | V | L | V | E | I | A | Q | R | I | R | E | D | I | T | D | R | P | I | H | L | T | T | E | D | S | R | N | I | I | S | L | H | P | R | D | Q | D | G | N | A | P | L | F | T | A | E |
Template Known Secondary structure |   |
. |  |  |  |  |  |  |  | . | T | T |
| S |  |  |  |  | T | T | G | G | G |
|
|
|
| S | . | . | . | . | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |
|
|  |  |  |  |
|
| S | S |
|
|
| T | T | S |
|
|
| T | T | S |
|
| S | S |
| S |  |  |
Template Predicted Secondary structure |   |
. |  |  |  |  |  |  |  | . |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
| . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
246 | . | . | . | 250 | . | . | |
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | |
|
|
|
. | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . |
  |
  |   |
391 | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | N | Y | R | G | F | T | F | P | L | W | G | F | L | A | N | T | D | I | S | Y | D | P | Q | Q | I | D | A | Q | T | C | M | A | W | M | D | N | Y | R | A | G | L | S | H | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | Q | Q | L | R | M | F | N | Q | L | D | S | H | D | T | A | R | F | K |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |   |
Alig confidence |   |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |
Template Sequence |   |
W | N | D | D | . |
F | H | N | A | V | H | V | F | A | T | G | E | T | Q | A | Y | Y | N | D | F | A | D | A | P | E | K | H | L | A | R | A | L | A | E | G | F | A | Y | Q | G | E | I | S | P | Q | T | G | E | P | R | G | V | K | S | T | G | Q | P | P | V | A | F | V | D | F | I | Q | N | H | D | Q | V | G | N | R |
Template Known Secondary structure |   |
 |
|  |  | . |  |  |  |  |  |  |  |  |  |  |
|
|
| S | G | G | G | G | G | G |
| S |
|  |  |  |  |  |  |  |  |  |  |  | S |
| S |
| S | S |
| B |
| T | T | T | S | S | B |
|
|
|
|
| T | T | S |
| G | G | G |  |  |  |
| S |
|
|  |  |  |  |  | T | S |
Template Predicted Secondary structure |   |
 |
|  |  | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
320 | . | . | . | |
. | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . |
  |
  |   |
454 | . | . | . | . | |
|
|
|
|
. | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
| . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
T | L | L | G | R | . |
. |
. |
. |
. |
D | I | A | R | L | P | L | A | V | V | W | L | F | T | W | P | G | V | P | C | I | Y | Y | G | D | E | V | G | L | D | G | K | N | D | P | F | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|   |
|   |
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |   |   |   |   |
|   |
|
|   |
|   |
|
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
A | Q | G | D | R | L | I | T | L | A | G | A | E | R | T | K | V | L | L | A | T | L | L | L | S | P | H | I | P | L | L | F | M | G | E | E | Y | G | E | S | R | P | F | L | F | F | T | D | F | H | G | D | L | A | R | A | V | R | E | G | R | A | K | E | F | A | D | H | A | G | E | N | V | P | D | P | N | A | P | E |
Template Known Secondary structure |   |
T | T |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | S |  |  |  |  |  | T | T | G | G | G | T |
|
| S |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | G | G | G | T | T |
|
|
|
|
| T | T | S |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
399 | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
495 | . | . | . | . | 500 | . | . | . | . | . | . | |
|
. | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | |
|
|
|
|
. | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |
| . | . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
C | R | K | P | F | P | W | Q | V | E | K | Q | . |
. |
D | T | A | L | F | A | L | Y | Q | R | M | I | A | L | R | K | K | S | Q | A | L | R | . |
. |
. |
. |
. |
H | G | G | C | Q | V | L | Y | A | E | D | N | V | V | V | F | V | R | V | L | N | Q | Q | R | V | L | V | A | I | N | R | G | E | A | C | E | V |
Query Conservation |   |
. | . |   |
|   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |   |   |
|
|   | . | . | . | . | . |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |
|
|   |
|
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   | . |   |
Template Sequence |   |
T | F | Q | R | S | K | L | N | W | K | Q | Q | H | S | E | E | G | K | A | W | L | A | F | T | R | E | L | L | L | L | R | Q | K | H | I | V | P | L | L | S | A | A | R | E | S | S | G | T | V | L | Q | T | A | P | G | F | I | A | V | S | W | R | F | P | G | G | T | L | S | L | A | L | N | I | S | A | T | T | . |
V |
Template Known Secondary structure |   |
 |  |  | T | T | S |
|
|  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  | T | T |
|
| S |
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |
| S | S | S |
| . |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
| . |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
479 | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | |
. |
  |
  |   |
566 | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . |
Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | L | P | A | S | P | F | L | N | A | V | Q | W | Q | C | K | E | G | H | G | Q | L | T | D | G | I | L | A | L | P | A | I | S | A | T | V | W | M |
Query Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |
|
Template Sequence |   |
L | L | P | D | L | P | G | K | T | L | F | A | W | P | N | E | S | . |
. |
. |
. |
. |
. |
. |
. |
T | G | S | L | S | Q | H | S | L | I | V | R | L |
Template Known Secondary structure |   |
 |
|
|
|
|
| S |  |  |  |  |  |  | S |
|
|
| . | . | . | . | . | . | . | . | S | S |  |  |
| T | T |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
558 | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | . | 580 | . | . | . | . | . | . | . |
  |