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Job DescriptionP21517
Confidence96.93%DateThu Jan 5 11:38:27 GMT 2012
Rank183Aligned Residues327
% Identity12%Templatec1r46B_
PDB info PDB header:hydrolaseChain: B: PDB Molecule:alpha-galactosidase a; PDBTitle: structure of human alpha-galactosidase
Resolution3.25 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   180.........190. ........200.........210.........220.........230.........240.........250....
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Query Sequence  DGISEKLPYLKK. . . . . LGVTALYLNPVFKAPSVHKYDTEDYRHVDPQFGGDGALLRLRHNTQQLGMRLVLDGVFNHSGD
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Template Sequence  KLFMEMAELMVSEGWKDAGYEYLCIDDCWMAPQRDSE. . GRLQADPQRFPH. . GIRQLANYVHSKGLKLGIYADVGNK. .
Template Known Secondary structure  TTT



SS
B
SS

TT..S


B
TTT
TT..TTTTT
SSSB..
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   67..70.........80.........90.........100... ......110..... ....120.........130.........140
 
   255....260.........270.........280.........290.........300.........310.........320.........330....
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Query Sequence  SHAWFDRHNRGTGGACHNPESPWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGWR
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Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . TCAGFPGSFGYYDIDAQTFA. . . . . . DWGVDLLK
Template Known Secondary structure  ..............................................
TTSSB

TTT......T

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   141........150.........160 ........
 
   335....340.........350.........360.........370.........380.........390.........400.........410....
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Query Sequence  LDVVHMLGEAGGARNNMQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAMNYRGFTFPLWGFLANTDISYDPQ
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Template Sequence  FDGCYC. . . . DSLENLADGYKHMSLALNRTGRSIVYSC. . . . . . . . . . . . EWPLYMWPFQKPNYTEIRQYCNHWRNFADI
Template Known Secondary structure 

S
....SS
S

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TTTS


TTT
S
S


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   169170.... .....180.........190.........200.. .......210.........220.........230..
 
   415....420.........430.........440.........450.. .......460.........470.........480.........490...
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Query Sequence  QIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDTARF. KTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDP
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Template Sequence  DDSWKSIKSILDWTSFNQERIVDVAGPGGWNDPDMLVIGNFGLSWNQQVTQMALWAIM. . . AAPLFMSND. . . . . . . . . .
Template Known Secondary structure 
SSTTTTT
BTTB


B
TTSSSS
T...T


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   233......240.........250.........260.........270.........280.........290 .........
 
   494.....500.........510.........520.........530.........540.........550.........560. ........570
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Query Sequence  FCRKPFPWQVEKQDTALFALYQRMIALRKKSQALRHGGCQVLYAEDNVVVFVRVLNQQRVLVAINRGE. . . ACEVVLPAS
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Template Conservation  .........           
 
   
 
  
                            
   
             
 
Template Sequence  . . . . . . . . . LRHISPQAKALLQDKDVIAINQDPLGKQGYQLRQGDNFEVWERPLSGLAWAVAMINRQEIGGPRSYTIAVA
Template Known Secondary structure  .........TTS


T
TT




SSS

SSS



SSS
ST
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   300.........310.........320.........330.........340.........350.........360.........370
 
   571 ........580.........590.........600..
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Query Sequence  P. . . . . . . . . . . . . FLNAVQWQCKEGHGQLTDGILALPAISATVW
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Template Conservation   

         
 
 
 
     
       
   
 


   
Template Sequence  SLGKGVACNPACFITQLLPVKRKLGFYEWTSRLRSHINPTGTVLL
Template Known Secondary structure  TTBTTTBSSS
SS




SS

TT
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   371........380.........390.........400.........410.....
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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