|   |
27 | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
|
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . |
Predicted Secondary structure |   |
 |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | R | Q | R | D | E | A | E | F | T | G | V | D | D | I | P | V | R | F | V | R | F | R | A | Q | H | H | D | . |
. |
R | V | V | V | I | C | P | G | R | I | E | S | Y | V | K | Y | A | E | L | A | Y | D | L | F | H | L | G | F | D | V | L | I | I | D | H | R | G | Q | G | R | S | G | R | L | L | A | D | P | H | L |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . |
|   |
|
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|   |   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   | . | . |
|   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   | . | . | . |
Template Sequence |   |
H | F | L | P | P | G | V | W | R | Q | S | V | R | A | G | R | V | R | A | T | L | F | L | P | P | G | P | G | P | F | P | G | I | I | D | I | F | G | I | G | G | G | L | L | E | Y | R | . |
. |
A | S | L | L | A | G | H | G | F | A | T | L | A | L | A | Y | Y | N | F | E | D | L | P | N | N | M | D | N | . |
. |
. |
Template Known Secondary structure |   |
B | S | S |
| T | T |
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
| S | S | S |
|
| B |
|  |  |  |  |  |
|
| T | T |
| S |
|
|
|  |  | . | . |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |
| S | S | S | T | T | S |
| S | S |
| S |
| . | . | . |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  | . | . |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | |
|
. | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | |
|
|
  |
  |   |
105 | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | |
|
. | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | H | V | N | R | F | N | D | Y | V | D | D | L | A | A | F | W | Q | Q | E | V | Q | P | G | P | W | . |
. |
R | K | R | Y | I | L | A | H | S | M | G | G | A | I | S | T | L | F | L | Q | R | H | P | G | V | C | D | A | I | A | L | T | A | P | M | F | G | I | V | I | R | M | P | S | F | M | A | R | Q | I | L | N |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |
|   |
|   |
|   |
|
|   |
|
|
|   |   |
|   |   |   |
|   | . |
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
I | S | L | E | Y | F | E | E | A | V | C | Y | M | L | Q | H | P | Q | V | K | G | P | G | I | G | L | L | G | I | S | L | G | A | D | I | C | L | S | M | A | S | F | L | K | N | . |
V | S | A | T | V | S | I | N | G | S | G | I | S | G | N | T | A | I | N | Y | K | H | S | S | I | P | P |
Template Known Secondary structure |   |
. | . | . | . | . | . | . |  |  | T |  |  |  |  |  |  |  |  |  |  |  | T | S | T | T | B |
|
| S | S |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S | . |  |  |  |  |  |  |  | S |
|
| S | B |
|
| S | S |
|  |  |  | T | T |  |  |  |
|
|
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . |
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
203 | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | |
. | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . |
  |
  |   |
183 | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | A | E | A | H | P | R | F | R | D | G | Y | A | I | G | T | G | R | W | R | A | L | P | F | A | I | N | V | L | T | H | S | R | Q | R | Y | R | R | N | L | R | F | Y | A | D | D | P | T | I | R | V | G | G | P | T | Y | H | W | V | R | E | S | I | L | A | G | E | Q | V | L | A | G | A | G | D | D | A | T | P | T |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
L | G | Y | D | L | R | R | I | K | V | A | F | S | G | L | V | D | I | V | D | I | R | N | A | L | V | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | Y | K | N | P | S | M | I | P | I | E | K | A | Q | G | P | I |
Template Known Secondary structure |   |
|
| B |
| G | G | G |
|  |  |
| T | T | S |
|  |  |
| T | T |
| B |
|
|
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | G | G | G | S | T | T | B |
|
| G | G | G |
|
| S |
|  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|
|  |  |
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
275 | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . |
  |
  |   |
263 | . | . | . | . | . | . | 270 | . | . | . | . | . | . | |
. | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|
|
|
|
|  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
Query Sequence |   |
L | L | L | Q | A | E | E | E | R | V | V | D | N | R | . |
M | H | D | R | F | C | E | L | R | T | A | A | G | H | P | V | E | G | G | R | P | L | V | I | K | G | A | Y | H | E | I | L | F | E | K | D | A | M | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | S |
Query Conservation |   |
|
|
|   |
|   |   |
|   |   |
|   |   |   | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
|   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
Template Conservation |   |
|
|
|   |
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |
|   |
|   |   |
Template Sequence |   |
L | L | I | V | G | Q | D | D | H | N | W | R | S | E | L | Y | A | Q | T | V | S | E | R | L | Q | A | H | G | K | . |
. |
E | K | P | Q | I | I | C | Y | P | G | T | G | H | Y | I | E | P | P | Y | F | P | L | C | P | A | S | L | H | R | L | L | N | K | H | V | I | W | G | G | E | P | R | A | H | S | K | A | Q | E |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . |
|
|
|  |  |  |  |  | T | T |
|
| S |
|
|
| S | T | T |
|
|
|
|
|  |  |  |  | T | T | T | T |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
319 | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | |
|
. | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . |
  |
  |   |
317 | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | A | L | H | A | I | V | D | F | F | N | R | H | N |
Query Conservation |   |
  |   |   |   |   |
|   |   |
|
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |
|   |
|
|   |
|
|
|
Template Sequence |   |
D | A | W | K | Q | I | L | A | F | F | C | K | H | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
397 | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 |
  |