|   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | |
|
|
|
|
|
. | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | R | E | N | A | F | A | A | F | T | M | G | P | L | T | D | F | W | R | Q | R | D | E | A | E | F | T | G | V | D | D | I | P | V | R | F | V | R | F | R | A | . |
. |
. |
. |
. |
. |
Q | H | H | D | R | V | V | V | I | C | P | G | R | I | E | . |
. |
. |
. |
. |
S | Y | V | K | Y | A | E | L | A | Y | D | L | F |
Query Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . |   |   |   |   |
|   |
|
|   |   |
|
|   |   |   | . | . | . | . | . |
|   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
Template Sequence |   |
T | R | P | I | Q | I | P | S | T | A | A | S | P | D | P | T | S | S | S | P | V | L | T | K | D | L | A | L | N | P | L | H | N | T | F | V | R | L | F | L | P | R | H | A | L | Y | N | S | A | K | L | P | L | V | V | Y | F | H | G | G | G | F | I | L | F | S | A | A | S | T | I | F | H | D | F | C | C | E | M | A |
Template Known Secondary structure |   |
 |
|
| S |
|
|
| B |
|
|
|
|
|
| T | T | S | S |
| S |  |  |  |  |  |  |  |  |  | T | T | T | T |  |  |  |  |  |  |  |  | G | G | G | G | G | S |
|
|
|  |  |  |  |  |  |  |
|
| S | T | T | T | S |
|
| T | T | B |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
33 | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . |
  |
  |   |
79 | 80 | . | |
. | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |
|
| . |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
H | L | G | . |
F | D | V | L | I | I | D | H | R | G | Q | G | R | S | G | R | L | L | A | D | P | H | L | G | H | V | N | R | F | N | D | Y | V | D | D | L | A | A | F | W | Q | Q | E | V | Q | . |
. |
. |
. |
. |
. |
. |
. |
P | G | P | W | R | K | R | Y | I | L | A | H | S | M | G | G | A | I | S | T | L | F | L |
Query Conservation |   |
  |   |
| . |
|   |
|   |   |   |
|   |
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|   |
|
|   |   |   |
|
Alig confidence |   |
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   |   |   |   |
|
|
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |
|
|
|
|   |
|
|   |   |   |
|
Template Sequence |   |
V | H | A | G | V | V | I | A | S | V | D | Y | R | L | A | P | E | H | R | L | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | Y | D | D | A | M | E | A | L | Q | W | I | K | D | S | R | D | E | W | L | T | N | F | A | D | F | S | N | C | F | I | M | G | E | S | A | G | G | N | I | A | Y | H | A | G |
Template Known Secondary structure |   |
 |  |  | T |
|  |  |  |  |  |  |
|
|
| T | T | T | T |
| T | T | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
113 | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . |
  |
  |   |
150 | . | |
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
Predicted Secondary structure |   |
 |
| . | . | . | . | . | . | . | . |
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | R | . |
. |
. |
. |
. |
. |
. |
. |
H | P | G | V | C | D | A | I | A | L | T | A | P | M | F | G | I | V | I | R | M | P | S | F | M | A | R | Q | I | L | N | W | A | E | A | H | P | R | F | R | D | G | Y | A | I | G | T | G | R | W | R | A | L | P | F | A | I | N | V | L | T | H | S | R | Q | R | Y | R | R | N |
Query Conservation |   |
  |   | . | . | . | . | . | . | . | . |   |
|   |   |
|   |   |
|
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
L | R | A | A | A | V | A | D | E | L | L | P | L | K | I | K | G | L | V | L | D | E | P | G | F | G | G | S | K | R | T | G | S | E | L | R | L | A | N | D | S | R | L | P | T | F | V | L | D | L | I | W | E | L | S | L | P | M | G | A | D | R | D | H | E | Y | C | N | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
 |  |  |  |  | T |  |  |  |  | T | T |
|
|  |  |  |  |  |  |  | S |
|
|
|
|
| S | S |
|
|  |  |  |  |  | T | T | T |
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |  | S |
| T | T |
|
| T | T | S | T | T | T |
|
| . | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
  |
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | F | Y | A | D | D | P | T | I | R | V | G | G | P | T | Y | H | W | V | R | E | S | I | L | A | G | E | Q | V | L | A | G | A | G | D | D | A | T | P | T | L | L | L | Q | A | E | E | E | R | V | V | D | N | R | M | H | D | R | F | C | E | L | R | T | A | A | G | H | P | V | E | G | G | R | P | L | V | I | K |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |
|
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |
|
|   |   |
|   |   |
| . | . |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   | . | . | . |   |
|   |
|   |   |   |   |
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | P | L | Y | S | F | D | K | I | R | S | L | G | W | R | V | M | V | V | G | C | H | G | D | . |
. |
P | M | I | D | R | Q | M | E | L | A | E | R | L | E | K | K | G | V | . |
. |
. |
D | V | V | A | Q | F | D | V |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  | T | T |
| . | . | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| . | . | . |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
| . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . |
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | |
|
. | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | |
|
|
. | . | . | . | . | . | . | . |
  |
  |   |
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | A | Y | H | E | I | L | F | E | K | D | A | M | R | S | V | A | L | H | A | I | V | D | F | F |
Query Conservation |   |
  |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|   |   |
|
|
Template Sequence |   |
G | G | Y | H | A | V | K | L | E | D | P | E | K | A | K | Q | F | F | V | I | L | K | K | F | V |
Template Known Secondary structure |   |
S |
|
| T | T | G | G | G | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
303 | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . |
  |