Job Description P0A7H0 Confidence 99.69% Date Thu Jan 5 11:05:39 GMT 2012 Rank 18 Aligned Residues 198 % Identity 21% Template c3g5uB_ PDB info PDB header:membrane protein Chain: B: PDB Molecule:multidrug resistance protein 1a; PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding Resolution 3.80 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		14	.	.	.	.	.	20	.	.	.	.		.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.
Predicted Secondary structure													.
Query SS confidence													.
Query Sequence		I	E	T	A	D	L	A	L	S	P	G	.	F	N	F	L	V	G	A	N	G	S	G	K	T	S	V	L	E	A	I	Y	T	L	G	H	G	R	A	F	R	S	L	Q	I	G	R	V	I	R	H	E	Q	E	A	F	V	L	H	G	R	L	Q	G	E	E	R	E	T	A	I	G	L	T	K	D	K	Q	G	D
Query Conservation													.
Alig confidence													.																										.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	Q	G	L	S	L	E	V	K	K	G	Q	T	L	A	L	V	G	S	S	G	C	G	K	S	T	V	V	Q	L	L	E	R	F	Y	D	P	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	M	A
Template Known Secondary structure				S							S	S	S							S	S	S	T	T									T	T	S	S			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S
Template Predicted Secondary structure																																							.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1049	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.																																										.	.
		93	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	K	V	R	I	D	G	T	D	G	H	K	V	A	E	L	A	H	L	M	P	M	Q	L	I	T	P	E	G	F	T	L	L	N	G	G	P	K	Y	R	R	A	F	L	D	W	G	C	F	H	N	E	P	G	F	F	T	A	W	S	N	L	K	R	L	L	K	Q	R	N	A	A	L	R	Q	V	T	R	Y	E
Query Conservation
Alig confidence																.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		G	S	V	F	L	D	G	K	E	I	K	Q	L	N	.	V	Q	W	L	R	A	Q	L	G	I	V	S	Q	E	P	I	L	F	D	C	S	I	A	E	N	I	A	Y	G	D	N	S	R	V	V	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure						S	S	S	S		B	T	S	S		.					T	T	S						S	S					S	S	B						T				S	S					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																.																																					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1088	.	1090	.	.	.	.	.	.	.	.	.	1100	.		.	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.
		173	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Q	L	R	P	W	D	K	E	L	I	P	L	A	E	Q	I	S	T	W	R	A	E	Y	S	A	G	I	A	A	D	M	A	D	T	C	K	Q	F	L	P	E	F	S	L	T	F	S	F	Q	R	G	W	E	K	E	T	E	Y	A	E	V	L	E	R	N	F	E	R	D	R	Q	L	T	Y	T	A	H	G	P	H
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	E	E	I	V	R	A	A	K	E	A	N	I	H	Q	F	I	D
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.												T						S
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																																																																1138	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.
		253	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.			.	.	.	.	.	.	330
Predicted Secondary structure																																																																									.	.
Query SS confidence																																																																									.	.
Query Sequence		K	A	D	L	R	I	R	A	D	G	A	P	V	E	D	T	L	S	R	G	Q	L	K	L	L	M	C	A	L	R	L	A	Q	G	E	F	L	T	R	E	S	G	R	R	C	L	Y	L	I	D	D	F	A	S	E	L	D	D	E	R	R	G	L	L	A	S	R	L	K	A	T	.	.	Q	S	Q	V	F	V	S
Query Conservation																																																																									.	.
Alig confidence																																			.	.	.	.	.	.	.	.	.																														.	.
Template Conservation																																			.	.	.	.	.	.	.	.	.
Template Sequence		S	L	P	D	K	Y	N	T	R	V	G	D	K	G	T	Q	L	S	G	G	Q	K	Q	R	I	A	I	A	R	A	L	V	R	.	.	.	.	.	.	.	.	.	Q	P	H	I	L	L	L	D	E	A	T	S	A	L	D	T	E	S	E	K	V	V	Q	E	A	L	D	K	A	R	E	G	R	T	C	I	V	I
Template Known Secondary structure		S	T	T	T	G	G	G		B		S	T	T	S		S	S																	.	.	.	.	.	.	.	.	.			S	S					S		S	S	S																	S	S	S	S
Template Predicted Secondary structure																																			.	.	.	.	.	.	.	.	.
Template SS confidence
		1156	.	.	.	1160	.	.	.	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.										.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.
		331	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	I	S	A	E	H	V	I	D	M	S	D	E	N	S	K	M	F	T	V	E	K	G	K	I	T	D
Query Conservation
Alig confidence												.	.	.	.
Template Conservation												.	.	.	.
Template Sequence		A	H	R	L	S	T	I	Q	N	A	.	.	.	.	D	L	I	V	V	I	Q	N	G	K	V	K	E
Template Known Secondary structure			S		T	T	G	G	G	S		.	.	.	.	S							T	B
Template Predicted Secondary structure												.	.	.	.
Template SS confidence
		1227	.	.	1230	.	.	.	.	.	.					.	.	.	1240	.	.	.	.	.	.	.	.	.

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions