|   |
439 | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | R | E | V | L | V | N | K | K | L | K | Q | A | Q | R | L | Y | E | K | N | Q | Q | G | R | M | I | F | M | K | N | I | G | D | A | L | K | E | P | A | Q | S | L | A | E | S | A | A | K | L | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | P | E | S | K | Q | L | A | N | Q | A | D | V | L | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | W | Y | I | Q | S | L | M | D | L | V | E | F | H | E | K | S | P | D | D | Q | K | A | L | S | D | F | V | D | T | L | I | K | V | R | N | R | H | H | N | V | V | P | T | M | A | Q | G | I | I | E | Y | K | A | C | T | V | D | P | V | T | N | Q | N | L | Q | Y | F | L | D | R | F | Y | M | N | R | I | S | T | R |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | G | G | G | G | S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| T | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . |
  |
  |   |
504 | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | |
|
|
|
. | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
R | L | V | D | E | I | Q | L | A | N | M | L | A | D | D | S | W | K | S | E | T | . |
. |
. |
. |
V | L | F | S | V | Q | D | L | I | D | E | V | V | P | S | V | L | P | A | I | K | . |
. |
. |
. |
. |
. |
. |
R | K | G | L | Q | L | L | I | N | N | H | L | K | A | H | D | M | R | R | G | D | R | D | A | L | R | R |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
Template Sequence |   |
M | L | M | N | Q | H | I | L | I | F | S | D | S | Q | T | G | N | P | S | H | I | G | S | I | D | P | N | C | D | V | V | A | V | V | Q | D | A | F | E | C | S | R | M | L | C | D | Q | Y | Y | L | S | S | P | E | L | K | L | T | Q | V | N | G | K | F | P | D | Q | P | I | H | I | V | Y | V | P | S | H | L | H | H |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
| S | S |
|
|
|
| T | T | S | B | T | T | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  |  | S | S | S | T | T | S |
|
|  |  |  |  |
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 |
  |
  |   |
573 | . | . | . | . | . | . | 580 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | L | L | L | L | M | Q | Y | A | V | T | S | T | . |
. |
. |
. |
. |
. |
. |
. |
Q | L | G | K | I | T | L | E | V | D | Q | D | E | S | S | E | D | R | L | T | F | R | I | L | D | T | G | E | G | V | S | I | H | E | M | D | N | L | H | F | P | F | I | N | Q | T | Q | N | D | R | Y | G | K | A | D | P | L | A | F |
Query Conservation |   |
|
|   |
|
|
|   |
|
|
|   |   |   | . | . | . | . | . | . | . | . |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|
|
|   |
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |
|   |
|   |   |   |   |   | . | . | . |   |   |   |
|   |
|   |
|   |
|   |
|   |
|
|   |   |
|   |   |   |   |
|
|   |   |
|   |
|
|   |   | . |   |   |   |   |   |
|   |
|
|
|
|
Template Sequence |   |
M | L | F | E | L | F | K | N | A | M | R | A | T | V | E | H | Q | E | N | Q | P | S | L | T | P | I | E | V | I | V | V | L | G | . |
. |
. |
K | E | D | L | T | I | K | I | S | D | R | G | G | G | V | P | L | R | I | I | D | R | L | F | S | Y | T | Y | S | T | A | P | . |
T | P | P | L | A | G | F | G | Y | G | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S | S | S |
|
|
|  |  |  |  |  |  |  |
| . | . | . | S | S |  |  |  |  |  |  |  |  |
| S |
|
|
|
| G | G | G | T | T | G | G | G | S | T | T |
|
| S | S |
| . |
|
|
|
| S | S | S |
|
|  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  | . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
251 | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | |
|
|
. | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | |
. | . | . | . | 320 | . | . | . | . | . | . |
  |
  |   |
645 | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
W | L | S | D | Q | L | A | R | K | L | G | G | H | L | N | I | K | T | R | D | G | L | G | T | R | Y | S | V | H | I | K | M | L | A | A | D | P | E | V | E |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |
|   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|   |
Template Sequence |   |
P | I | S | R | L | Y | A | K | Y | F | Q | G | D | L | N | L | Y | S | L | S | G | Y | G | T | D | A | I | I | Y | L | K | A | L | S | S | E | S | I | E | K |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  | S | S | T | T | T |
| B |
|
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
335 | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . |
  |