|   |
439 | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | R | E | V | L | V | N | K | K | L | K | Q | A | Q | R | L | Y | E | K | N | Q | Q | G | R | M | I | F | M | K | N | I | G | D | A | L | K | E | P | A | Q | S | L | A | E | S | A | A | K | L | N | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | E | S | K | Q | L | A | N | Q | A | D | V | L | V | R |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | W | Y | I | Q | S | L | Q | E | L | L | D | F | K | D | K | S | A | E | D | A | K | A | I | Y | D | F | T | D | T | V | I | R | I | R | N | R | H | N | D | V | I | P | T | M | A | Q | G | V | I | E | Y | K | E | S | F | D | P | V | T | S | Q | N | V | Q | Y | F | L | D | R | F | Y | M | S | R | I | S | I | R | M |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | G | G | G | T | T | S |
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
112 | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . |
  |
  |   |
505 | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | V | D | E | I | Q | L | A | N | M | L | A | D | D | S | W | K | S | E | T | V | L | F | S | V | Q | D | L | I | D | E | V | V | P | S | V | L | P | A | I | K | R | . |
. |
. |
. |
. |
. |
. |
K | G | L | Q | L | L | I | N | N | H | L | K | A | H | D | M | R | R | G | D | R | D | A | L | R | R | I | L | L | L | L |
Query Conservation |   |
  |   |   |   |
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |   |
|
|   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|   |   |
|
|   |
|
|
Template Sequence |   |
L | L | N | Q | H | S | L | L | F | G | . |
. |
. |
. |
H | I | G | S | I | N | P | N | C | N | V | L | E | V | I | K | D | G | Y | E | N | A | R | R | L | C | D | L | Y | Y | I | N | S | P | E | L | E | L | E | E | L | N | A | K | S | P | G | Q | P | I | Q | V | V | Y | V | P | S | H | L | Y | H | M | V | F | E | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |
| . | . | . | . |
| B | T | T | B |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
|
|
|  |  |  |  |  |  |  | S | S | S | T | T | S |
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  | . | . | . | . |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
194 | . | . | . | . | . | 200 | . | . | . | |
|
|
|
. | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . |
  |
  |   |
578 | . | 580 | . | . | . | . | . | |
|
|
|
|
|
|
|
. | . | . | . | 590 | . | . | . | . | . | . | . | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
. | |
630 | . | . | . | . | . | . | . | . | . | 640 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |
| . | . | . | . | . | . | . | . |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  | . | . | . | . | . | . |  | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
M | Q | Y | A | V | T | S | T | . |
. |
. |
. |
. |
. |
. |
. |
Q | L | G | K | I | T | L | E | V | D | Q | D | E | S | S | E | D | R | L | T | F | R | I | L | D | T | G | E | G | V | S | I | H | E | M | D | N | L | H | F | P | F | I | . |
. |
. |
. |
. |
. |
N | . |
Q | T | Q | N | D | R | Y | G | K | A | D | P | L |
Query Conservation |   |
|   |
|
|
|   |   |   | . | . | . | . | . | . | . | . |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |
|
|   |   |   |   |   |   |   |
|
|   |   |
|   | . | . | . | . | . | . |   | . |   |   |   |   |   |   |   |   |   |
|
|
|
|
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   | . | . | . |   |   |   |
|   |
|   |
|   |
|   |
|   |
|
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
Template Sequence |   |
F | K | N | A | M | R | A | T | M | E | H | H | A | N | R | G | V | Y | P | P | I | Q | V | H | V | T | L | G | . |
. |
. |
N | E | D | L | T | V | K | M | S | D | R | G | G | G | V | P | L | R | K | I | D | R | L | F | N | Y | M | Y | S | T | A | P | R | P | R | V | E | T | S | R | A | V | P | L | A | G | F | G | Y |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | S | T | T | T | T |
|
|
|
|  |  |  |  |  |  |  |
| . | . | . | S | S |  |  |  |  |  |  |  |  |
| S |
|
|
|
|  |  |  |  | G | G | G | G |
| T | T | T | T |
|
|
|
|
|
| S | S |
|
| S |
|
|
| S | S |
| T | T |
|
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
| . | . | . |
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
281 | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | |
|
|
. | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . |
  |
  |   |
643 | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . | . | . | . | 680 | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | F | W | L | S | D | Q | L | A | R | K | L | G | G | H | L | N | I | K | T | R | D | G | L | G | T | R | Y | S | V | H | I | K | M | L | A | A | D | P | E | V | E | E | E |
Query Conservation |   |
|
|   |
|   |   |   |   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |
|
|   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|   |
|   |
|   |   |
|   |   |   |
|
|   |
|   |
|   |
|   |   |
|   |
|
|   |   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
G | L | P | I | S | R | L | Y | A | Q | Y | F | Q | G | D | L | K | L | Y | S | L | E | G | Y | G | T | D | A | V | I | Y | I | K | A | L | S | T | D | S | I | E | R | L | P |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  | S | S | T | T | T |
| B |
|
|
|
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
358 | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . |
  |