|   |
21 | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
50 | . | . | . | . | . | . | . | . | . | |
|
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | |
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
| . | . | . | . | . | . |
|
|  |  |  |  |  |  |
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
Query Sequence |   |
Q | A | V | N | V | T | V | A | Y | Q | T | S | A | E | P | A | K | V | A | Q | A | D | N | T | F | A | K | E | S | . |
. |
. |
. |
. |
. |
G | A | T | V | D | W | R | K | F | D | . |
. |
. |
S | G | A | S | I | V | R | A | L | A | S | G | D | V | Q | I | G | N | L | G | S | S | P | L | A | V | . |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |
|
|   |   | . | . | . | . | . | . |
|
|
|
|
|   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
Template Conservation |   |
|
|   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |
|   |
|   |
|   |
|   |
|   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
Template Sequence |   |
P | K | V | T | W | R | L | A | S | S | F | P | K | S | L | D | T | I | F | G | G | A | E | V | L | S | K | X | L | S | E | A | T | D | G | N | F | Q | I | Q | V | F | S | A | G | E | L | V | P | G | L | Q | A | A | D | A | V | T | E | G | T | V | E | C | C | H | T | V | G | Y | Y | Y | W | G | K | D | P | T | F | A |
Template Known Secondary structure |   |
|
|  |  |  |  |  |  |  | S | S |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | T |
|  |  |  |  |  |  |
| T | T | S | S | S |
| G | G | G |  |  |  |  |  |  | T | T | S | S | S |  |  |  |  |
| G | G | G | G | T | T | T |
| T |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
86 | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | A | S | Q | Q | V | P | I | E | V | F | L | L | A | S | K | L | G | N | S | E | A | L | V | V | K | K | T | I | S | K | P | E | D | L | I | G | K | R | I | A | V | P | F | I | S | T | T | H | Y | S | L |
Query Conservation |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |
|
|
|
|
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |
Alig confidence |   |
. | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   | . |   |   |   |
|
|   |
|   |   |
|
|
|
|   |
|
|
|   |   |
| . | . | . | . | . | . |   |   |
Template Sequence |   |
L | A | A | A | V | P | F | S | L | S | A | R | G | I | N | A | W | H | Y | H | G | G | G | I | D | L | Y | N | E | F | L | S | Q | H | N | I | V | A | F | P | G | G | N | T | G | V | Q | X | G | G | W | . |
F | R | R | E | I | N | T | V | A | D | X | Q | G | L | K | X | R | V | G | G | . |
. |
. |
. |
. |
. |
F | A |
Template Known Secondary structure |   |
 | T | T |
|
| T | T |
|
|
|  |  |  |  |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  | G | G | G | T |  |  |  |  |  |  |  |  |
|
| S | B |
|
|  |  | . |  | S | S |
|
|
| S | S | G | G | G | T | T |
|  |  |  |
|
|  | . | . | . | . | . | . |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . |
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | |
. | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | |
|
|
|
|
|
. | . |
  |
  |   |
138 | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | A | A | L | K | H | W | G | I | K | P | G | Q | V | E | I | V | N | L | Q | P | P | A | I | I | A | A | W | Q | R | G | D | I | D | G | A | Y | V | W | A | P | A | V | N | A | L | E | K | D | G | K | V | L | T | D | S | E | Q | V | G | Q | W | G | A | P | T | L | D | V | W | V | V | R | K | D | F | A | E | K | H |
Query Conservation |   |
  |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|
|
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |
| . | . | . | . | . |
|   |
|   |   |   |
|
|
|   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|
Template Sequence |   |
G | K | V | X | E | R | L | G | V | V | P | . |
. |
. |
. |
. |
Q | Q | I | A | G | G | D | I | Y | P | A | L | E | K | G | T | I | D | A | T | E | W | V | G | P | Y | D | D | E | K | L | G | F | F | K | V | A | P | Y | Y | Y | Y | P | G | W | W | E | G | G | P | T | V | H | F | X | F | N | K | S | A | Y | E | G | L |
Template Known Secondary structure |   |
 |  |  |  |  | T | T | T |
|  |  | . | . | . | . | . |  |
|
|
| G | G | G |  |  |  |  |  |  |  | T | S |
| S |  |  |
|
|
|
|  |  |  |  |  | T | T | T | G | G | G | T |
|
|  |  |  |  |
| B | T | T |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  | . | . | . | . | . |  |  |  |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
183 | . | . | . | . | . | . | 190 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . |
  |
  |   |
218 | . | 220 | . | . | . | . | . | |
. | . | . | . | 230 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  | . |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | E | V | V | K | A | F | A | . |
K | S | A | I | D | A | Q | Q | P | Y | I | A | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | D | V | W | L | K | Q | P | E | N | I | S | K | L | A | R | L | S | G | V | P | E | G | D | V | P | G | L | V | K | G | N | T | Y | L |
Query Conservation |   |
|
|   |   |   |   |
|   | . |   |
|   |   |   |
|   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   | . |
Template Sequence |   |
T | P | T | Y | Q | S | L | L | R | T | A | C | H | A | A | D | A | N | X | L | Q | L | Y | D | W | K | N | P | T | A | I | K | S | L | V | A | Q | G | T | Q | L | R | P | F | S | P | E | I | L | Q | A | C | F | E | A | A | N | E | V | Y | A | E | X | E | A | S | N | P | A | F | K | K | I | W | D | S | I | K | A | . |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  | . |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
258 | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | |
  |
  |   |
274 | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | P | Q | Q | Q | T | A | E | L | T | G | P | V | N | K | A | I | I | D | T | A | Q | F | L | K | E | Q | G | K | V |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|
Alig confidence |   |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
. |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
. |
F | R | S | E | H | Y | T | W | A | Q | I | A | E | Y | N | Y | D | T | F | X | X | V | Q | Q | N | A | G | K | L |
Template Known Secondary structure |   |
. |  |  |  |  |  |  |  |  | T | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|
|
Template Predicted Secondary structure |   |
. |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
337 | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . |
  |