Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	Q	A	R	V	K	W	V	E	G	L	T	F	L	G	E	S	A	S	G	H	Q	I	L	M	D	G	N	S	G	D	K	A	P	S	P	M	E	M	V	L	M	A	A	G	G	C	S	A	I	D	V	V	S	I	L	Q	K	G	R
Secondary structure
SS confidence
Disorder		?																												?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		Q	D	V	V	D	C	E	V	K	L	T	S	E	R	R	E	E	A	P	R	L	F	T	H	I	N	L	H	F	I	V	T	G	R	D	L	K	D	A	A	V	A	R	A	V	D	L	S	A	E	K	Y	C	S	V	A	L	M	L	E
Secondary structure
SS confidence
Disorder																			?	?																																								?
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.
Sequence		K	A	V	N	I	T	H	S	Y	E	V	V	A	A
Secondary structure
SS confidence
Disorder														?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1ml8 chain A Region: 1 - 134 Aligned: 131 Modelled: 134 Confidence: 100.0% Identity: 99% Fold: OsmC-like Superfamily: OsmC-like Family: YhfA-like Phyre2 PDB 1vla chain A Region: 2 - 134 Aligned: 132 Modelled: 132 Confidence: 100.0% Identity: 36% Fold: OsmC-like Superfamily: OsmC-like Family: YhfA-like Phyre2 PDB 2egt chain A Region: 2 - 131 Aligned: 124 Modelled: 130 Confidence: 100.0% Identity: 36% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein aq_1549; PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus Phyre2 PDB 2onf chain A domain 1 Region: 2 - 132 Aligned: 129 Modelled: 131 Confidence: 100.0% Identity: 19% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 2pn2 chain A domain 1 Region: 3 - 129 Aligned: 123 Modelled: 127 Confidence: 99.9% Identity: 15% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1qwi chain A Region: 2 - 130 Aligned: 128 Modelled: 129 Confidence: 99.9% Identity: 14% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1lql chain E Region: 2 - 131 Aligned: 127 Modelled: 130 Confidence: 99.9% Identity: 16% PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae Phyre2 PDB 1lql chain A Region: 2 - 131 Aligned: 127 Modelled: 130 Confidence: 99.9% Identity: 16% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 3eer chain A Region: 2 - 129 Aligned: 125 Modelled: 128 Confidence: 99.9% Identity: 11% PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein, putative; PDBTitle: high resolution structure of putative organic hydroperoxide resistance2 protein from vibrio cholerae o1 biovar eltor str. n16961 Phyre2 PDB 2opl chain A domain 1 Region: 2 - 130 Aligned: 127 Modelled: 129 Confidence: 99.9% Identity: 22% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 2bjo chain A Region: 2 - 130 Aligned: 127 Modelled: 129 Confidence: 99.9% Identity: 13% PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb; PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis Phyre2 PDB 1ukk chain A Region: 2 - 132 Aligned: 129 Modelled: 131 Confidence: 99.9% Identity: 16% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1nye chain D Region: 2 - 130 Aligned: 128 Modelled: 129 Confidence: 99.9% Identity: 15% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1n2f chain A Region: 2 - 131 Aligned: 128 Modelled: 130 Confidence: 99.9% Identity: 12% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 2ql8 chain A Region: 2 - 129 Aligned: 124 Modelled: 128 Confidence: 99.9% Identity: 10% PDB header:oxidoreductase Chain: A: PDB Molecule:putative redox protein; PDBTitle: crystal structure of a putative redox protein (lsei_0423) from2 lactobacillus casei atcc 334 at 1.50 a resolution Phyre2 PDB 1usp chain A Region: 2 - 129 Aligned: 126 Modelled: 128 Confidence: 99.9% Identity: 10% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 3cje chain A Region: 2 - 131 Aligned: 128 Modelled: 130 Confidence: 99.9% Identity: 16% PDB header:oxidoreductase Chain: A: PDB Molecule:osmc-like protein; PDBTitle: crystal structure of an osmc-like hydroperoxide resistance protein2 (jann_2040) from jannaschia sp. ccs1 at 1.70 a resolution Phyre2 PDB 2d7v chain A domain 1 Region: 1 - 127 Aligned: 126 Modelled: 127 Confidence: 99.9% Identity: 20% Fold: OsmC-like Superfamily: OsmC-like Family: Ohr/OsmC resistance proteins Phyre2 PDB 1zb8 chain B Region: 2 - 129 Aligned: 125 Modelled: 128 Confidence: 99.9% Identity: 11% PDB header:oxidoreductase Chain: B: PDB Molecule:organic hydroperoxide resistance protein; PDBTitle: crystal structure of xylella fastidiosa organic peroxide resistance2 protein Phyre2 PDB 1ljm chain A Region: 1 - 25 Aligned: 25 Modelled: 25 Confidence: 26.5% Identity: 28% Fold: Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily: p53-like transcription factors Family: RUNT domain Phyre2 1 d1ml8a_ 2 d1vlaa_ 3 c2egtA_ 4 d2onfa1 5 d2pn2a1 6 d1qwia_ 7 c1lqlE_ 8 d1lqla_ 9 c3eerA_ 10 d2opla1 11 c2bjoA_ 12 d1ukka_ 13 d1nyed_ 14 d1n2fa_ 15 c2ql8A_ 16 d1uspa_ 17 c3cjeA_ 18 d2d7va1 19 c1zb8B_ 20 d1ljma_ 21 22 23 24 25 26 27 28

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1ml8a_ 100.0 99 Fold:OsmC-like Superfamily:OsmC-like Family:YhfA-like 2 d1vlaa_ 100.0 36 Fold:OsmC-like Superfamily:OsmC-like Family:YhfA-like 3 c2egtA_ 100.0 36 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:hypothetical protein aq_1549; PDBTitle: crystal structure of hypothetical protein (aq1549) from aquifex2 aeolicus 4 d2onfa1 100.0 19 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 5 d2pn2a1 99.9 15 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 6 d1qwia_ 99.9 14 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 7 c1lqlE_ 99.9 16 PDB header:unknown function Chain: E: PDB Molecule:osmotical inducible protein c like family; PDBTitle: crystal structure of osmc like protein from mycoplasma2 pneumoniae 8 d1lqla_ 99.9 16 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 9 c3eerA_ 99.9 11 PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein, putative; PDBTitle: high resolution structure of putative organic hydroperoxide resistance2 protein from vibrio cholerae o1 biovar eltor str. n16961 10 d2opla1 99.9 22 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 11 c2bjoA_ 99.9 13 PDB header:oxidoreductase Chain: A: PDB Molecule:organic hydroperoxide resistance protein ohrb; PDBTitle: crystal structure of the organic hydroperoxide resistance2 protein ohrb of bacillus subtilis 12 d1ukka_ 99.9 16 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 13 d1nyed_ 99.9 15 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 14 d1n2fa_ 99.9 12 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 15 c2ql8A_ 99.9 10 PDB header:oxidoreductase Chain: A: PDB Molecule:putative redox protein; PDBTitle: crystal structure of a putative redox protein (lsei_0423) from2 lactobacillus casei atcc 334 at 1.50 a resolution 16 d1uspa_ 99.9 10 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 17 c3cjeA_ 99.9 16 PDB header:oxidoreductase Chain: A: PDB Molecule:osmc-like protein; PDBTitle: crystal structure of an osmc-like hydroperoxide resistance protein2 (jann_2040) from jannaschia sp. ccs1 at 1.70 a resolution 18 d2d7va1 99.9 20 Fold:OsmC-like Superfamily:OsmC-like Family:Ohr/OsmC resistance proteins 19 c1zb8B_ 99.9 11 PDB header:oxidoreductase Chain: B: PDB Molecule:organic hydroperoxide resistance protein; PDBTitle: crystal structure of xylella fastidiosa organic peroxide resistance2 protein 20 d1ljma_ 26.5 28 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:p53-like transcription factors Family:RUNT domain 21 d1eaqa_ not modelled 25.7 24 Fold:Common fold of diphtheria toxin/transcription factors/cytochrome f Superfamily:p53-like transcription factors Family:RUNT domain 22 d1xo3a_ not modelled 21.8 13 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:C9orf74 homolog 23 c2qjlA_ not modelled 16.6 22 PDB header:signaling protein Chain: A: PDB Molecule:ubiquitin-related modifier 1; PDBTitle: crystal structure of urm1 24 d2qqra2 not modelled 10.9 22 Fold:SH3-like barrel Superfamily:Tudor/PWWP/MBT Family:Tudor domain 25 d1wgka_ not modelled 10.3 13 Fold:beta-Grasp (ubiquitin-like) Superfamily:MoaD/ThiS Family:C9orf74 homolog 26 d2qqsa2 not modelled 10.3 26 Fold:SH3-like barrel Superfamily:Tudor/PWWP/MBT Family:Tudor domain 27 c3kl7A_ not modelled 7.9 12 PDB header:hydrolase Chain: A: PDB Molecule:putative metal-dependent hydrolase; PDBTitle: crystal structure of putative metal-dependent hydrolase2 (yp_001302908.1) from parabacteroides distasonis atcc 8503 at 2.30 a3 resolution 28 d1v5ta_ not modelled 5.9 13 Fold:beta-Grasp (ubiquitin-like) Superfamily:Ubiquitin-like Family:Ubiquitin-related

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0