|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
70 | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
| . | . | . | . | . | . |
|
|  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
Query Sequence |   |
A | S | V | Q | L | Q | N | V | T | K | A | W | G | E | V | V | V | S | K | D | I | N | L | D | I | H | E | G | E | F | V | V | F | V | G | P | S | G | C | G | K | S | T | L | L | R | M | I | A | G | L | E | T | I | T | S | G | D | L | F | I | G | E | K | R | M | N | D | . |
. |
. |
. |
. |
. |
T | P | P | A | E | R |
Query Conservation |   |
  |   |
|   |   |   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |
|   |   |
|   |
|   |   |   |
|   |   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
|   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |
|
|
|   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
A | E | V | K | L | I | N | I | W | K | R | F | G | D | V | T | A | V | K | D | L | S | L | E | I | K | D | G | E | F | L | V | L | L | G | P | S | G | C | G | K | T | T | T | L | R | X | I | A | G | L | E | E | P | T | R | G | Q | I | Y | I | E | D | N | L | V | A | D | P | E | K | G | V | F | V | P | P | K | E | R |
Template Known Secondary structure |   |
| S |  |  |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |
| T | T |
|  |  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  | T | S | S |
|
| S |  |  |  |  |  |  | T | T |  |  |  |  |  | G | G | G | T |  |  |
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . |
  |
  |   |
76 | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | V | G | M | V | F | Q | S | Y | A | L | Y | P | H | L | S | V | A | E | N | M | S | F | G | L | K | L | A | G | A | K | K | E | V | I | N | Q | R | V | N | Q | V | A | E | V | L | Q | L | A | H | L | L | D | R | K | P | K | A | L | S | G | G | Q | R | Q | R | V | A | I | G | R | T | L | V | A | E | P | S | V | F |
Query Conservation |   |
  |
|   |   |
|   |
|   |   |   |
|   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|
|
|
|   |   |   |
|   |
|
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |
|
|
|   |
|
|   |
|
|   |   |   |
|   |
|
|
Template Sequence |   |
D | V | A | X | V | F | Q | S | Y | A | L | Y | P | H | X | T | V | Y | D | N | I | A | F | P | L | K | L | R | K | V | P | K | Q | E | I | D | K | R | V | R | E | V | A | E | X | L | G | L | T | E | L | L | N | R | K | P | R | E | L | S | G | G | Q | R | Q | R | V | A | L | G | R | A | I | I | R | R | P | K | V | F |
Template Known Secondary structure |   |
T |  |  |  |
|
|
| S |
|
|
|
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| G | G | G | T | T |
|
| G | G | G | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
85 | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . |
  |
  |   |
156 | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | L | D | E | P | L | S | N | L | D | A | A | L | R | V | Q | M | R | I | E | I | S | R | L | H | K | R | L | G | R | T | M | I | Y | V | T | H | D | Q | V | E | A | M | T | L | A | D | K | I | V | V | L | D | A | G | R | V | A | Q | V | G | K | P | L | E | L | Y | H | Y | P | A | D | R | F | V | A | G | F | I | G |
Query Conservation |   |
|
|
|
|
|   |
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |
|   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | X | D | E | P | L | S | N | L | D | A | K | L | R | V | K | X | R | A | E | L | K | K | L | Q | R | Q | L | G | V | T | T | I | Y | V | T | H | D | Q | V | E | A | X | T | X | G | D | R | I | A | V | X | N | K | G | E | L | Q | Q | V | G | T | P | D | E | V | Y | Y | K | P | V | N | T | F | V | A | G | F | I | G |
Template Known Secondary structure |   |
 |  |  | S | T | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |
| S |  |  |  |  |  |  | T | T |  |  |  |  |  |  |
|  |  |  |  |  |  | S |
| S | B |  |  |  |  |  |  | S | S |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
165 | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . |
  |
  |   |
236 | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | P | K | M | N | F | L | P | V | K | V | T | A | T | A | I | D | Q | V | Q | V | E | L | P | M | P | N | R | Q | Q | V | W | L | P | V | E | S | R | D | V | Q | V | G | A | N | M | S | L | G | I | R | P | E | H | L | L | P | . |
. |
. |
. |
. |
. |
S | D | I | A | D | V | I | L | E | G | E | V | Q | V | V | E | Q |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | P | P | X | N | F | L | D | A | T | I | T | D | D | G | F | L | D | F | G | E | F | K | L | . |
. |
K | L | L | Q | D | Q | F | E | V | L | E | E | E | N | X | V | G | K | E | V | I | F | G | I | R | P | E | D | V | H | D | A | S | F | T | H | I | D | V | P | E | E | N | T | V | K | A | T | V | D | I | I | E | N |
Template Known Secondary structure |   |
S | S |
|
|  |  |  |  |  |  |  |
| T | T | S |  |  |  |
| S | S |
|  |  | . | . |  |
|
|  |  |  |  |  |  |  |  |  | T | T |
| T | T |
|  |  |  |  |  |  |
| G | G | G |  |  |  | G | G | G |
| S |
|
|
| T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
245 | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | |
|
. | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |
  |   |
310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | G | N | E | T | Q | I | H | I | Q | I | P | S | I | R | Q | N | L | V | Y | R | Q | N | D | V | V | L | V | E | E | G | A | T | F | A | I | G | L | P | P | E | R | C | H | L | F | R | E | D | G | T | A | C |
Query Conservation |   |
  |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   | . | . |   |   |
|   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Template Sequence |   |
L | G | G | E | K | I | V | H | L | R | R | G | N | I | S | F | T | A | K | F | P | K | E | . |
. |
S | K | V | R | E | G | D | E | V | S | V | V | F | D | X | K | K | I | H | I | F | R | K | D | T | E | K | A |
Template Known Secondary structure |   |
| S | S |  |  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |  | T | T | . | . |
|
|
|
| T | T |
|  |  |  |  |  |  |
| G | G | G |
|  |  |  |  | T | T | T |
| B | B |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
| . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
323 | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | |
|
. | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . |
  |