|   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . |
Predicted Secondary structure |   |
 |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |
|
|  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | E | I | A | D | L | K | V | H | F | E | I | K | D | G | K | Q | W | F | W | Q | P | P | K | T | L | K | A | V | D | G | V | T | L | R | L | Y | E | G | E | T | L | G | V | V | G | E | S | G | C | G | K | S | T | F | A | R | A | I | I | G | L | V | K | A | T | D | G | H | V | A | W | L | G | K | E | L | L | G | M |
Query Conservation |   |
|
|
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|   |
|   |   |
|
|
|   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|
|   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |
|
|   |   |
|
|   |   |
|   |   |
|
|   |
|
|
|
|
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   |   |   |   |   |   |
|   |
|   |
|   |
|   |   |
|   |   |   |
Template Sequence |   |
V | Q | F | S | G | V | V | F | N | Y | P | T | R | P | S | I | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
P | V | L | Q | G | L | S | L | E | V | K | K | G | Q | T | L | A | L | V | G | S | S | G | C | G | K | S | T | V | V | Q | L | L | E | R | F | Y | D | P | M | A | G | S | V | F | L | D | G | K | E | I | K | Q | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |
|
| S |
| G | G | G |
| . | . | . | . | . | . | . | . | . | . |
| S |  |  | S |
|
|  |  |  |
| S | S | S |  |  |  |  |  |
| S | S | S | T | T |  |  |  |  |  |  |  |  | T | T | S | S |
|
| S |  |  |  |  |  | S | S | S | S |
| B | T | S | S |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1031 | . | . | . | . | . | . | . | . | 1040 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | 1050 | . | . | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 |
  |
  |   |
92 | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | |
|
|
|
. | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|  |  |  | . | . | . | . |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
Query Sequence |   |
K | P | D | E | W | R | A | V | R | S | D | I | Q | M | I | F | Q | D | P | L | A | S | L | N | P | R | M | T | I | G | E | I | I | A | E | P | L | R | T | Y | H | P | K | M | S | R | Q | E | V | R | E | R | V | K | A | M | M | L | K | V | G | L | L | P | N | L | I | N | R | Y | P | H | E | . |
. |
. |
. |
F | S | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |
|   |
|   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . |
|
|
|
Alig confidence |   |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   | . | . | . |   |
|
|   |   |
|   |   |
|
|
|   |   |   | . | . |
|
|   |   | . |
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |   |
|   |   |   |
|   |   |
|
|   |
Template Sequence |   |
N | V | Q | . |
. |
. |
W | L | R | A | Q | L | G | I | V | S | Q | E | P | I | . |
. |
L | F | D | C | . |
S | I | A | E | N | I | A | Y | G | D | N | S | R | V | V | S | Y | E | E | I | V | R | A | A | K | E | A | N | I | H | Q | F | I | D | S | L | P | D | K | Y | N | T | R | V | G | D | K | G | T | Q | L | S | G |
Template Known Secondary structure |   |
|  |  | . | . | . |  |  | T | T | S |
|  |  |  |  | S | S |
|
| . | . |
|
| S | S | . | B |  |  |  |  |  | T |
|
|
| S | S |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  | S | S | T | T | T | G | G | G |
| B |
| S | T | T | S |
| S | S |
|  |
Template Predicted Secondary structure |   |
|  |  | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
| . | . |
|
|
|
| . |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1101 | . | . | |
|
|
. | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | |
|
. | . | 1120 | . | |
. | . | . | . | . | . | . | . | 1130 | . | . | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . |
  |
  |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | Q | C | Q | R | I | G | I | A | R | A | L | I | L | E | P | K | L | I | I | C | D | E | P | V | S | A | L | D | V | S | I | Q | A | Q | V | V | N | L | L | Q | Q | L | Q | R | E | M | G | L | S | L | I | F | I | A | H | D | L | A | V | V | K | H | I | S | D | R | V | L | V | M | Y | L | G | H | A | V | E | L | G |
Query Conservation |   |
|   |   |
|
|
|   |
|
|   |
|
|   |   |   |
|   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|
|
|   |   |   |   |   |   |   |
|
|
|   |
|
|   |   |
|   |
|
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|
|
|
|
|   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   | . | . |   |   |
|
|
|   |
|
|
|   |   |   |   |   |   | . |   |   |
|   |
|   |
|
|   |   |
|   |
|   |
|   |
|
Template Sequence |   |
G | Q | K | Q | R | I | A | I | A | R | A | L | V | R | Q | P | H | I | L | L | L | D | E | A | T | S | A | L | D | T | E | S | E | K | V | V | Q | E | A | L | D | K | A | R | E | . |
. |
G | R | T | C | I | V | I | A | H | R | L | S | T | I | Q | . |
N | A | D | L | I | V | V | I | Q | N | G | K | V | K | E | H | G |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
| S | S |  |  |  |  | S |
| S | S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S | . | . | S | S |
|  |  |  |  |
| S |
| T | T | G | G | G | . | S |
| S |  |  |  |  |  |  | T | B |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| . | . |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  | . |  |
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1175 | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . | . | . | . | . | . | . | . | . | |
|
1220 | . | . | . | . | . | . | . | . | . | 1230 | . | . | . | . | |
. | . | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . |
  |
  |   |
248 | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | Y | D | E | V | Y | H | N | P | L | H | P | Y | T | R | A | L | M | S | A |
Query Conservation |   |
  |   |   |
|
|   |   |   |
|   |
|
|
|
|   |   |
|   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   | . |   |
|   |   |   | . |   |
|   |   |   |
Template Sequence |   |
T | H | Q | Q | L | L | A | Q | . |
K | G | I | Y | F | . |
S | M | V | S | V |
Template Known Secondary structure |   |
|  |  |  |  |  |  | S | . |
| S |  |  |  | . |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
| . |
|
|  |  |  | . |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1252 | . | . | . | . | . | . | . | |
1260 | . | . | . | . | |
. | . | . | . | . |
  |