Phyre 2 Results for P64570

Email	l.a.kelley@imperial.ac.uk
Description	P64570
Date	Thu Jan 5 12:09:31 GMT 2012
Unique Job ID	238f6a1048b937cc

Summary

Top model

Image coloured by rainbow N → C terminus

Model (left) based on template c1dxzA_

Top template information

PDB header:transmembrane protein
Chain: A: PDB Molecule:acetylcholine receptor protein, alpha chain;
PDBTitle: m2 transmembrane segment of alpha-subunit of nicotinic2 acetylcholine receptor from torpedo californica, nmr, 203 structures

Confidence and coverage

Confidence:

7.1%

Coverage:

10%

7 residues ( 10% of your sequence) have been modelled with 7.1% confidence by the single highest scoring template.

You may wish to submit your sequence to Phyrealarm. This will automatically scan your sequence every week for new potential templates as they appear in the Phyre2 library.

Please note: You must be registered and logged in to use Phyrealarm.

3D viewing

Interactive 3D view in Jmol

Sequence analysis

Secondary structure and disorder prediction

1 . . . . . . . . 10 . . . . . . . . . 20 . . . . . . . . . 30 . . . . . . . . . 40 . . . . . . . . . 50 . . . . . . . . . 60

Sequence M G I T S A G M Q S R D A E C G E R I F T R T V R Q V K Q Q T T V H Y F V S P P R P P V K T N P Q A K T L I S T R L E V

Secondary structure

SS confidence

Disorder ? ? ? ? ? ? ?
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? ?

Disorder confidence

. . . . . . . . . 70 .

Sequence A T R K K R R V L F I

Secondary structure

SS confidence

Disorder ? ? ?
?
? ? ?

Disorder confidence

Confidence Key
High(9) Low (0)

? Disordered

Alpha helix

Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank	Aligned region

Detailed template information

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server

Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]

If you use the binding site predictions from 3DLigandSite, please also cite:

3DLigandSite: predicting ligand-binding sites using similar structures.

Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]

Imperial College London

Lawrence Kelley, Benjamin Jefferys

Disclaimer

Terms and Conditions

Component software

Template detection: HHpred 1.51

Secondary structure prediction: Psi-pred 2.5

Disorder prediction: Disopred 2.4

Transmembrane prediction: Memsat_SVM

Multi-template modelling and ab initio: Poing 1.0