Job Description P12998 Confidence 100.00% Date Wed Jan 25 15:20:38 GMT 2012 Rank 64 Aligned Residues 330 % Identity 13% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		37	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.			.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.			100	.	.	.	.	.	.	.	.	.	110	.	.
Predicted Secondary structure																																																.	.																		.	.
Query SS confidence																																																.	.																		.	.
Query Sequence		D	D	R	Q	Y	L	N	F	S	S	N	D	Y	L	G	L	S	H	H	P	Q	I	I	R	A	W	Q	Q	G	A	E	Q	F	G	I	G	S	G	G	S	G	H	V	S	G	Y	.	.	S	V	V	H	Q	A	L	E	E	E	L	A	E	W	L	G	Y	.	.	S	R	A	L	L	F	I	S	G	F	A	A	N
Query Conservation																																																.	.																		.	.
Alig confidence														.				.																														.	.																		.	.
Template Conservation														.				.
Template Sequence		K	D	E	N	A	I	Y	F	L	G	N	S	.	L	G	L	.	Q	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	E	K	E	I	A	L	M	N	A	L	T	V	N	L
Template Known Secondary structure		T	T		B					B	T	T	T	.	S			.	B		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			G	G	G					S
Template Predicted Secondary structure														.				.
Template SS confidence
		64	.	.	.	.	.	70	.	.	.	.	.		.	.	.		.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.
		113	.	.	.	.	.	.	120	.	.				.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.										.	.	.	.	.	.	150	.	.	.						.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.
Predicted Secondary structure												.	.	.																						.	.	.	.	.	.	.	.	.											.	.	.	.	.
Query SS confidence												.	.	.																						.	.	.	.	.	.	.	.	.											.	.	.	.	.
Query Sequence		Q	A	V	I	A	A	M	M	A	K	.	.	.	E	D	R	I	A	A	D	R	L	S	H	A	S	L	L	E	A	A	S	L	S	.	.	.	.	.	.	.	.	.	P	S	Q	L	R	R	F	A	H	N	.	.	.	.	.	D	V	T	H	L	A	R	L	L	A	S	P	C	P	G	Q	Q	M	V	V	T	E
Query Conservation												.	.	.																						.	.	.	.	.	.	.	.	.											.	.	.	.	.
Alig confidence												.	.	.																						.	.	.	.	.	.	.	.	.											.	.	.	.	.
Template Conservation
Template Sequence		H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L	F	S
Template Known Secondary structure													S	S	S							T	T																T	T														T	T		S	S														G	G	G
Template Predicted Secondary structure
Template SS confidence
		142	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.
		176	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.				.	.	.	.	.	.	.	250	.	.
Predicted Secondary structure																																																																					.	.	.
Query SS confidence																																																																					.	.	.
Query Sequence		G	V	F	S	M	D	G	D	S	A	P	L	A	E	I	Q	Q	V	T	Q	Q	H	N	G	W	L	M	V	D	D	A	H	G	T	G	V	I	G	E	Q	G	R	G	S	C	W	L	Q	K	V	K	P	E	L	L	V	V	T	F	G	K	G	F	G	V	S	G	.	.	.	A	A	V	L	C	S	S	T	V	A
Query Conservation																																																																					.	.	.
Alig confidence																																										.	.	.	.	.	.																						.	.	.
Template Conservation																																										.	.	.	.	.	.
Template Sequence		G	V	H	F	Y	T	G	Q	H	F	N	I	P	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	N	V	E	L	Y	.	.	.	.	.	.	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A	F	I	H	E	K	H	A
Template Known Secondary structure		S	B		T	T	T		B	B													T	T								T	T	T	T	T	T	S				.	.	.	.	.	.					T								S	S	S	T	T				T	T									G	G	G	T
Template Predicted Secondary structure																																										.	.	.	.	.	.
Template SS confidence
		222	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.							.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.
		253	.	.	.	.	.	.	260	.	.	.	.																								.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.
Predicted Secondary structure														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		D	Y	L	L	Q	F	A	R	H	L	I	Y	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	S	T	S	M	P	P	A	Q	A	Q	A	L	R	A	S	L	A	V	I	R	S	D	E	G	D	A	R	R	E	K	L	A	A	L	I	T	R	F	R	A	G	V	Q	D	L
Query Conservation														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation
Template Sequence		H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L	E	Y	L	I	K	H	N
Template Known Secondary structure		T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		296	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.
				310	.	.	.	.	.	.	.						.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.		.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.
Predicted Secondary structure		.	.									.	.	.	.	.																																																.
Query SS confidence		.	.									.	.	.	.	.																																																.
Query Sequence		.	.	P	F	T	L	A	D	S	C	.	.	.	.	.	S	A	I	Q	P	L	I	V	G	D	N	S	R	A	L	Q	L	A	E	K	L	R	Q	Q	G	C	W	V	T	A	I	R	P	P	T	V	P	A	G	T	A	R	L	R	L	T	L	.	T	A	A	H	E	M	Q	D	I	D	R	L	L	E	V	L	H
Query Conservation		.	.									.	.	.	.	.																																																.
Alig confidence		.	.									.	.	.	.	.														.	.																.	.	.	.	.	.	.											.
Template Conservation																														.	.																.	.	.	.	.	.	.
Template Sequence		Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	P	N	K	.	.	D	V	F	Q	E	L	E	K	R	G	V	V	C	D	K	.	.	.	.	.	.	.	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F	H	D	V	Y	K	F	T	N	L	L	T
Template Known Secondary structure									S		S	S	G	G	G	B		S									T	T		.	.								T	T	T						.	.	.	.	.	.	.		T	T	T					B			T	T	T
Template Predicted Secondary structure																														.	.																.	.	.	.	.	.	.
Template SS confidence
		376	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.			.	.	.	.	.	.	410	.	.	.	.	.	.	.	.								.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.	.	.	.	.	440	.	.	.	.	.	.
		382	.
Predicted Secondary structure
Query SS confidence
Query Sequence		G	N
Query Conservation
Alig confidence
Template Conservation
Template Sequence		S	I
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		456	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions