Job Description P77806 Confidence 99.95% Date Thu Jan 5 12:33:00 GMT 2012 Rank 138 Aligned Residues 331 % Identity 12% Template c3e9kA_ PDB info PDB header:hydrolase Chain: A: PDB Molecule:kynureninase; PDBTitle: crystal structure of homo sapiens kynureninase-3-hydroxyhippuric acid2 inhibitor complex Resolution 1.70 Å

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		28	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.						.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.
Predicted Secondary structure																																	.	.	.	.	.
Query SS confidence																																	.	.	.	.	.
Query Sequence		Q	Q	H	Q	A	I	N	L	S	Q	G	F	P	D	F	D	G	P	R	Y	L	Q	E	R	L	A	H	H	V	A	Q	.	.	.	.	.	G	A	N	Q	Y	A	P	M	T	G	V	Q	A	L	R	E	A	I	A	Q	K	T	E	R	L	Y	G	Y	Q	P	D	A	D	S	D	I	T	V	T	A	G	A	T	E
Query Conservation																																	.	.	.	.	.
Alig confidence																		.															.	.	.	.	.																														.	.	.
Template Conservation																		.																																																	.	.	.
Template Sequence		K	D	E	N	A	I	Y	F	L	G	N	S	L	G	L	Q	.	P	K	M	V	K	T	Y	L	E	E	E	L	D	K	W	A	K	I	A	A	Y	G	H	E	V	G	K	R	P	W	I	T	G	D	E	S	I	V	G	L	M	K	D	I	V	G	A	N	.	.	.	E	K	E	I	A	L	M	N	A	L	T	V
Template Known Secondary structure		T	T		B					B	T	T	T	S			B	.		T	T																G	G	G	G	G	T	S	S	S	S		G	G	G	T	T					G	G	G					T			.	.	.	G	G	G					S
Template Predicted Secondary structure																		.																																																	.	.	.
Template SS confidence
		64	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.		80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.				.	.	130	.	.	.	.	.	.	.	.	.
		103	.	.	.	.	.	.	110	.	.	.	.				.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.									.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160				.	.	.	.	.	.	.	.
Predicted Secondary structure														.	.	.																						.	.	.	.	.	.	.	.																										.	.	.
Query SS confidence														.	.	.																						.	.	.	.	.	.	.	.																										.	.	.
Query Sequence		A	L	Y	A	A	I	T	A	L	V	R	N	.	.	.	G	D	E	V	I	C	F	D	P	S	Y	D	S	Y	A	P	A	I	A	L	S	.	.	.	.	.	.	.	.	G	G	I	V	K	R	M	A	L	Q	P	P	H	F	R	V	D	W	Q	E	F	A	A	L	L	.	.	.	S	E	R	T	R	L	V	I
Query Conservation														.	.	.																						.	.	.	.	.	.	.	.																										.	.	.
Alig confidence														.	.	.																						.	.	.	.	.	.	.	.																										.	.	.
Template Conservation
Template Sequence		N	L	H	L	L	M	L	S	F	F	K	P	T	P	K	R	Y	K	I	L	L	E	A	K	A	F	P	S	D	H	Y	A	I	E	S	Q	L	Q	L	H	G	L	N	I	E	E	S	M	R	M	I	K	P	R	E	G	E	E	T	L	R	I	E	D	I	L	E	V	I	E	K	E	G	D	S	I	A	V	I	L
Template Known Secondary structure															S	S	S							T	T																T	T														T	T		S	S														G	G	G
Template Predicted Secondary structure
Template SS confidence
		140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.
		169	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	N	T	P	H	N	P	S	A	T	V	W	Q	Q	A	D	F	A	A	L	W	Q	A	I	A	G	H	E	I	F	V	I	S	D	E	V	Y	E	H	I	N	F	S	Q	Q	G	H	A	S	V	L	A	H	P	Q	L	R	E	R	A	V	A	V	S	S	F	G	K	T	Y	H	M	T	G	W	K	V	G	Y	C
Query Conservation
Alig confidence																	.	.	.																							.	.	.	.	.	.	.	.
Template Conservation																	.	.	.																							.	.	.	.	.	.	.	.
Template Sequence		F	S	G	V	H	F	Y	T	G	Q	H	F	N	I	P	.	.	.	A	I	T	K	A	G	Q	A	K	G	C	Y	V	G	F	D	L	A	H	A	V	G	.	.	.	.	.	.	.	.	N	V	E	L	Y	L	H	D	W	G	V	D	F	A	C	W	C	S	Y	K	Y	L	N	A	G	A	G	G	I	A	G	A
Template Known Secondary structure				S	B		T	T	T		B	B					.	.	.									T	T								T	T	T	T	T	.	.	.	.	.	.	.	.	T	S								T								S	S	S	T	T				T	T
Template Predicted Secondary structure																	.	.	.																							.	.	.	.	.	.	.	.
Template SS confidence
		220	.	.	.	.	.	.	.	.	.	230	.	.	.	.				.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.									.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.
		249	250	.	.	.	.	.	.	.																										.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.		.	.	290	.	.	.	.	.	.	.	.	.	300	.	.
Predicted Secondary structure											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.
Query SS confidence											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.
Query Sequence		V	A	P	A	P	I	S	A	E	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	I	R	K	V	H	Q	Y	L	T	F	S	V	N	T	P	A	Q	L	A	L	A	D	M	L	R	A	E	P	E	H	.	Y	L	A	L	P	D	F	Y	R	Q	K	R	D	I	L
Query Conservation											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.
Alig confidence											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																															.
Template Conservation
Template Sequence		F	I	H	E	K	H	A	H	T	I	K	P	A	L	V	G	W	F	G	H	E	L	S	T	R	F	K	M	D	N	K	L	Q	L	I	P	G	V	C	G	F	R	I	S	N	P	P	I	L	L	V	C	S	L	H	A	S	L	E	I	F	K	Q	A	T	M	K	A	L	R	K	K	S	V	L	L	T	G	Y	L
Template Known Secondary structure					G	G	G	T	T	T	S			S	S			G	G	G	B						T	T			S				B		S	S	G	G	G	G			S
Template Predicted Secondary structure
Template SS confidence
		289	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.
		303	.	.	.	.	.			.	310	.	.	.	.	.	.	.	.					.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370				.	.	.
Predicted Secondary structure								.	.											.	.	.	.																																																					.	.	.
Query SS confidence								.	.											.	.	.	.																																																					.	.	.
Query Sequence		V	N	A	L	N	E	.	.	S	R	L	E	I	L	P	C	E	G	.	.	.	.	T	Y	F	L	L	V	D	Y	S	A	V	S	T	L	D	D	V	E	F	C	Q	W	L	T	Q	E	H	G	V	A	A	I	P	L	S	V	F	C	A	D	P	F	P	H	K	L	I	R	L	C	F	A	.	.	.	K	K	E
Query Conservation								.	.											.	.	.	.																																																					.	.	.
Alig confidence								.	.											.	.	.	.											.	.	.	.										.										.	.	.	.	.	.	.	.												.	.	.
Template Conservation																																		.	.	.	.										.										.	.	.	.	.	.	.	.
Template Sequence		E	Y	L	I	K	H	N	Y	G	V	V	N	I	I	T	P	S	H	V	E	E	R	G	C	Q	L	T	I	T	F	S	V	.	.	.	.	P	N	K	D	V	F	Q	E	L	.	E	K	R	G	V	V	C	D	K	.	.	.	.	.	.	.	.	R	N	P	N	G	I	R	V	A	P	V	P	L	Y	N	S	F
Template Known Secondary structure																S		S	S	G	G	G	B		S									.	.	.	.	T	T								.		T	T	T						.	.	.	.	.	.	.	.		T	T	T					B			T	T	T
Template Predicted Secondary structure																																		.	.	.	.										.										.	.	.	.	.	.	.	.
Template SS confidence
		369	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400					.	.	.	.	.	.	.	.	.		410	.	.	.	.	.	.	.	.									.	420	.	.	.	.	.	.	.	.	.	430	.	.	.	.	.
		374	.	.	.	.	.	380	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	T	L	L	A	A	A	E	R	L	R	Q	L
Query Conservation
Alig confidence
Template Conservation
Template Sequence		H	D	V	Y	K	F	T	N	L	L	T	S	I
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		445	.	.	.	.	450	.	.	.	.	.	.	.

No model constructed - rank, confidence too low

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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions