|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | |
|
. | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
| . |
|  |  |
|
|
|
|  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | T | Q | R | V | V | I | T | P | G | E | P | A | G | I | G | P | D | L | V | . |
. |
V | Q | L | A | Q | R | E | W | P | V | E | L | V | V | C | A | D | A | T | L | L | T | N | R | A | A | M | L | G | L | P | L | T | . |
L | R | P | Y | S | P | N | S | P | A | Q | P | Q | T | A | G | T | L | T | L | L | P | V | A |
Query Conservation |   |
  |   |   |   |
|
|
|
|   |
|
|
|
|
|
|
|
|
|
|   | . | . |
|
|
|
|   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   | . |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |   |   |   |
|
|   |   |   |
|   |
| . | . | . | . |   |   |
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |   |
|
|
|
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |
Template Sequence |   |
K | D | V | K | I | V | F | P | E | G | L | D | . |
. |
. |
. |
E | R | I | L | E | A | V | S | K | L | A | G | N | K | V | L | N | P | I | V | I | G | N | E | N | E | I | Q | A | K | A | K | E | L | N | L | T | L | G | G | V | K | I | Y | D | P | H | T | Y | E | G | M | E | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Template Known Secondary structure |   |
S |
|
|  |  |  |  | S |
| T | T |
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S | S |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  | T | T | T |
|
|
| T | T |
|  |  |  |
| T | T | T |
| T | T |  |  |  | . | . | . | . | . | . | . | . | . | . |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
15 | . | . | . | . | 20 | . | . | . | . | . | . | |
|
|
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | |
|
|
|
|
|
|
|
|
|
  |
  |   |
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | |
|
. | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  | . | . |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | R | A | P | V | T | A | G | Q | L | A | V | E | N | G | H | Y | V | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
V | E | T | L | A | R | A | C | D | G | C | L | N | G | E | F | A | A | L | I | T | . |
. |
G | P | V | H | K | G | V | I | N | D | A | G | I | P | F | T | G | H | T | E | F | F | E | E | R | S | Q |
Query Conservation |   |
  |   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|
| . | . |
|
|   |
|
|
|   |
|   |   |
|
|   |   |   |   |
|
|
|
|   |
|   |   |   |   |
|
Alig confidence |   |
. | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
Template Conservation |   |
. | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|
|   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |
|   |   |   |
|   |
|
|
|   |   | . | . | . | . | . | . | . |
|
|   |   |   |
|
Template Sequence |   |
. |
. |
. |
. |
. |
. |
. |
. |
L | V | Q | A | F | V | E | R | R | K | G | K | A | T | E | E | Q | A | R | K | A | L | L | D | E | N | Y | F | G | T | M | L | V | Y | K | G | L | A | D | G | L | V | S | G | A | A | H | S | T | A | D | T | V | R | P | A | L | Q | I | . |
. |
. |
. |
. |
. |
. |
I | K | T | K | E | G |
Template Known Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  | T | T | T | S | S |
|  |  |  |  |  |  |  | T | T | S |  |  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  | T | . | . | . | . | . | . | . | S |
| B |
| T | T |
Template Predicted Secondary structure |   |
. | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . |  |
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
|
|
|
|
|
|
|
|
81 | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
140 | . | . | . | . | . |
  |
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
. | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | |
|
|
. | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  | . | . | . |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
A | K | K | V | V | M | M | L | A | T | E | E | L | R | V | A | L | A | T | T | H | L | P | L | R | D | I | A | D | A | . |
. |
I | T | P | A | L | L | H | E | V | I | A | I | L | H | H | D | L | R | T | K | F | G | I | A | E | P | R | I | L | V | C | . |
. |
. |
G | L | N | P | H | A | G | E | G | G | H | M | G | T |
Query Conservation |   |
  |   |   |   |   |
|   |   |   |   |   |   |
|   |
|   |   |
|
|   |
|
|   |
|   |
|
|   |   |   | . | . |
|
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|
|   |   |
|
|
|
|
|
| . | . | . |   |
|
|
|
|
|
|
|   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
| . |
|
|
|
|
|
| . | . | . |
|
| . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   | . | . | . | . | . |   |   |
|   |
|   |
|   |   |
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|   | . |   |   |
|   |   | . |
|
|
|
|
|
|
|   |   |   |   | . | . | . | . |
|
|   |   |   |   |   |   |
Template Sequence |   |
V | K | K | T | S | G | V | F | I | M | A | R | G | E | E | Q | Y | V | . |
. |
. |
. |
. |
F | A | D | C | A | I | N | I | A | P | D | S | Q | D | L | A | E | I | A | I | E | S | A | N | T | A | K | . |
M | F | D | I | E | . |
P | R | V | A | M | L | S | F | S | T | K | . |
. |
. |
. |
G | S | A | K | S | D | E | T |
Template Known Secondary structure |   |
|
|
|
|  |  |  |  |  |  |  |  | T | T |  |  |  |  | . | . | . | . | . |  |  |
| S | S | S |
| S | S |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  | T | T |
|
| . |
|
|  |  |  |  |
| S | S | S | T | . | . | . | . | T | S | S |
| S |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  | . | . | . | . | . |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
| . |
|
|  |  |  |  |  |
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
146 | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | |
|
|
|
|
. | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
. | . | . | . | . | |
. | . | . | . | 200 | . | . | . | . | . | . | |
|
|
|
. | . | . | 210 | . | . | . | . |
  |
  |   |
221 | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | E | I | D | T | I | I | P | V | L | N | E | L | R | A | Q | G | M | K | L | N | G | P | L | P | A | D | T | L | F | Q | P | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | Y | L | D | N | A | D | A | V | L | A | M | Y | H | D | Q | G | L | P | V | L | K | Y | Q | G | F | G | R | G | V | N | I | T | L | G | L | P | F |
Query Conservation |   |
|
|   |   |   |
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |   |
|   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |
|   |
|
|   |
|
|
|
|
|
|   |
|   |
|
|   |
|   |
|   |   |   |
|
|   |
|
|
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|   |   |   |   |   | . |   |   |   |   |
|
|
|   |
|   |   |
|   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|   |
|
|
|
|
|   |
|
|
|   |
|
|
|
|   |   |
|   |   |   |   |   |   |   |   |   | . |   |   |
|   |
|
|
Template Sequence |   |
E | K | V | A | D | A | V | K | I | A | K | E | K | A | . |
P | E | L | T | L | D | G | E | F | Q | F | D | A | A | F | V | P | S | V | A | E | K | K | A | P | D | S | E | I | K | G | D | A | N | V | F | V | F | P | S | L | E | A | G | N | I | G | Y | K | I | A | Q | R | L | G | N | F | E | . |
A | V | G | P | I | L |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |
| . | T | T | S |
|  |  |  |  |  |
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
| S | S | S |
| S | S |
|
| S |  |  |  |
| S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  | . |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . |
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
215 | . | . | . | . | 220 | . | . | . | . | . | . | . | . | |
. | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | |
. | . | . | 290 | . | . |
  |
  |   |
291 | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | R | T | S | V | D | H | G | T | A | L | E | L | A | G | R | G | K | A | D | V | G | S | F | I | T | A | L | N | L | A | I | K | M | I |
Query Conservation |   |
|
|
|
|   |
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |   |   |
|   |   |   |
|
|   |   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |   |   |
| . | . | . | . | . |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |   |   |
|
Template Sequence |   |
Q | G | L | N | M | P | . |
. |
. |
. |
. |
V | N | D | L | S | R | G | C | N | A | E | D | V | Y | N | L | A | L | I | T | A | A | Q | A |
Template Known Secondary structure |   |
 | S | B | S | S |
| . | . | . | . | . |  |  |  |
|
| T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
| . | . | . | . | . |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
293 | . | . | . | . | . | |
|
|
|
|
. | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
  |