Return to main results Retrieve Phyre Job Id

Job DescriptionQ46939
Confidence99.98%DateThu Jan 5 12:35:58 GMT 2012
Rank39Aligned Residues263
% Identity22%Templatec3hhdC_
PDB info PDB header:transferase, hydrolaseChain: C: PDB Molecule:fatty acid synthase; PDBTitle: structure of the human fatty acid synthase ks-mat didomain2 as a framework for inhibitor design.
Resolution2.15 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   27..30.........40......... 50......... 60.........70.........80...
Predicted Secondary structure 





....

...................










Query SS confidence 






















. . . .









. . . . . . . . . . . . . . . . . . .























Query Sequence  VELGSLVVKALIERTGVPAYAVD. . . . EVILGQVLTA. . . . . . . . . . . . . . . . . . . GAGQNPARQSAIKGGLPNSVSAIT
Query Conservation    

  
   

 



    

.... 

 
     ...................      
   
  


        
Alig confidence 






















....









...................

















..



Template Conservation    
 
  
 


 


           

  
                              
  

    
 
..
  
Template Sequence  LRLLLEVTYEAIVDGGINPDSLRGTHTGVWVGVSGSETSEALSRDPETLVGYSMVGCQRAMMANRLSFFFDFRG. . PSIA
Template Known Secondary structure  TT

GGGGTTS




TS
TTT

TSTTT

S..
Template Predicted Secondary structure 























..
Template SS confidence 















































































   7980.........90.........100.........110.........120.........130.........140.........150.. ....
 
   84.....90.........100.........110.........120.........130.........140.........150.........160...
Predicted Secondary structure 








































Query SS confidence 















































































Query Sequence  INDVCGSGLKALHLATQAIQCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVTAEN
Query Conservation 
   
 
   

  
   
 

    


 
 
  
                                         
  
Alig confidence 
















































...............................
Template Conservation 
  





 

  
   
  
  
 




                  ...............................
Template Sequence  LDTACSSSLMALQNAYQAIHSGQCPAAIVGGINVLLKPNTSVQFLRLGM. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Template Known Secondary structure 

GGGTTS
S



T
...............................
Template Predicted Secondary structure 












...............................
Template SS confidence 















































































   157..160.........170.........180.........190.........200.....
 
   164.....170.........180.........190.........200.........210.........220.........230.........240...
Predicted Secondary structure 










































Query SS confidence 















































































Query Sequence  LAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQPRTDASAEGLARLNPSFDSLGSVTA
Query Conservation      

 
 
  
  
      
     
                       
   
                
   
  
Alig confidence  ...................................................................












Template Conservation  ...................................................................

     



  
Template Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . LSPEGTCKAFDTA
Template Known Secondary structure  ...................................................................B
TTS


TTBTT
Template Predicted Secondary structure  ...................................................................












Template SS confidence 















































































   206...210........
 
   244.....250.........260.........270.........280.... .....290.........300.........310.......
Predicted Secondary structure 


















......












Query SS confidence 








































. . . . . .
































Query Sequence  GNASSINDGAAAVMMMSEAKARALNLPVLARIRAFASVGVD. . . . . . PALMGIAPVYATRRCLERVGWQLAEVDLIEANE
Query Conservation         




 

 
   
   
      
 
       ......          
   

  


   


  
 

Alig confidence 




















....















......
































Template Conservation    
   



  



 
  
....  
 
 
 
     

        
        
  

  


    
  

 

Template Sequence  GNGYCRSEGVVAVLLTKKSLA. . . . RRVYATILNAGTNTDGFKEQGVTFPSGDIQEQLIRSLYQSAGVAPESFEYIEAHG
Template Known Secondary structure 


B
BB
GGG
....SS
S



TT
TTS

T

GGG


Template Predicted Secondary structure 



....
























Template SS confidence 















































































   219220.........230......... 240.........250.........260.........270.........280.........290....
 
   318. 320.........330.........340..... ....350.........360.......
Predicted Secondary structure 

.....












.

........................
Query SS confidence 

. . . . .

























.





















. . . . . . . . . . . . . . . . . . . . . . . .
Query Sequence  AF. . . . . AAQALSVGKMLEWDERRVNVNGGAIA. LGHPIGASGCRILVSLVHEMVK. . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation   
.....        
 


    

  

   . 


 



   
 
   


 ........................
Alig confidence 

.....

























.





















........................
Template Conservation 


   
  
  

   

        
 
 
  


   


   

   
 
    


                   
Template Sequence  TGTKVGDPQELNGITRALCATRQEPLLIGSTKSNMGHPEPASGLAALAKVLLSLEHGLWAPNLHFHSPNPEIPALLDGRL
Template Known Secondary structure 


TTSSS
SS

T
B
GGGTB



SS

SB
TT
TS
Template Predicted Secondary structure 




















































Template SS confidence 















































































   295....300.........310.........320.........330.........340.........350.........360.........370....
 
   368.370.........380.........390...
Predicted Secondary structure  ........









Query SS confidence  . . . . . . . .

























Query Sequence  . . . . . . . . RNARKGLATLCIGGGQGVALTIERDE
Query Conservation  ........  
  

     


   
  
    
Alig confidence  ........

























Template Conservation               
 




 

 
   

    
Template Sequence  QVVDQPLPVRGGNVGINSFGFGGSNVHIILRPNT
Template Known Secondary structure 

S

B

S

TTS

Template Predicted Secondary structure 



























Template SS confidence 

































   375....380.........390.........400........
 
Download:Text version

No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
© Structural Bioinformatics Group, Imperial College, London
Lawrence Kelley, Benjamin Jefferys 
Disclaimer
Terms and Conditions