Job Description P08192 Confidence 100.00% Date Thu Jan 5 11:00:51 GMT 2012 Rank 4 Aligned Residues 391 % Identity 30% Template c1o5zA_ PDB info PDB header:ligase Chain: A: PDB Molecule:folylpolyglutamate synthase/dihydrofolate synthase; PDBTitle: crystal structure of folylpolyglutamate synthase (tm0166) from2 thermotoga maritima at 2.10 a resolution Resolution 2.10 Å

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		12	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure
Query SS confidence
Query Sequence		P	L	A	S	W	L	S	Y	L	E	N	L	H	S	K	T	I	D	L	G	L	E	R	V	S	L	V	A	A	R	L	G	V	L	K	P	A	P	F	V	F	T	V	A	G	T	N	G	K	G	T	T	C	R	T	L	E	S	I	L	M	A	A	G	Y	K	V	G	V	Y	S	S	P	H	L	V	R	Y	T	E
Query Conservation
Alig confidence											.	.	.	.
Template Conservation											.	.	.	.
Template Sequence		A	Y	L	E	V	L	R	Y	L	.	.	.	.	Y	H	K	V	K	P	G	L	E	R	I	S	M	L	L	S	K	L	G	N	P	H	L	E	Y	K	T	I	H	I	G	G	T	N	G	K	G	S	V	A	N	M	V	S	N	I	L	V	S	Q	G	Y	R	V	G	S	Y	Y	S	P	H	L	S	T	F	R	E
Template Known Secondary structure											.	.	.	.		T						S										T	T		G	G	G	S	S								S	S	S																T									S		S	S		G	G	G
Template Predicted Secondary structure											.	.	.	.
Template SS confidence
		2	.	.	.	.	.	.	.	10					.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.							.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.
Predicted Secondary structure																									.	.	.	.	.	.
Query SS confidence																									.	.	.	.	.	.
Query Sequence		R	V	R	V	Q	G	Q	E	L	P	E	S	A	H	T	A	S	F	A	E	I	E	S	.	.	.	.	.	.	A	R	G	D	I	S	L	T	Y	F	E	Y	G	T	L	S	A	L	W	L	F	K	Q	A	Q	L	D	V	V	I	L	E	V	G	L	G	G	R	L	D	A	T	N	I	V	D	A	D	V	A	V
Query Conservation																									.	.	.	.	.	.
Alig confidence																									.	.	.	.	.	.
Template Conservation
Template Sequence		R	I	R	L	N	E	E	Y	I	S	E	E	D	V	V	K	I	Y	E	T	M	E	P	I	L	N	E	L	D	K	E	E	I	F	S	P	S	F	F	E	V	V	T	A	M	A	F	L	Y	F	A	E	K	N	V	D	I	A	V	L	E	V	G	L	G	G	R	L	D	A	T	N	V	V	F	P	L	C	S	T
Template Known Secondary structure		G				T	T																							T	T	S	T	T	T																			T	T		S							S	S	S	S	T	T		G	G	G	G				S
Template Predicted Secondary structure
Template SS confidence
		83	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.
		166	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.			.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.					.	.	.	.	.	.	.	.
Predicted Secondary structure																																										.	.																											.	.	.	.
Query SS confidence																																										.	.																											.	.	.	.
Query Sequence		V	T	S	I	A	L	D	H	T	D	W	L	G	P	D	R	E	S	I	G	R	E	K	A	G	I	F	R	S	E	K	P	A	I	V	G	E	P	E	M	.	.	P	S	T	I	A	D	V	A	Q	E	K	G	A	L	L	Q	R	R	G	V	E	W	N	Y	S	V	.	.	.	.	T	D	H	D	W	A	F	S
Query Conservation																																										.	.																											.	.	.	.
Alig confidence										.	.	.	.	.	.	.																										.	.																											.	.	.	.
Template Conservation										.	.	.	.	.	.	.
Template Sequence		I	V	T	V	D	R	Y	T	.	.	.	.	.	.	.	I	E	Q	I	A	W	E	K	S	G	I	I	K	E	R	V	P	L	V	T	G	E	R	K	R	E	A	L	K	V	M	E	D	V	A	R	K	K	S	S	R	M	Y	V	I	D	K	D	F	S	V	K	V	K	S	L	K	L	H	E	N	R	F	D	Y
Template Known Secondary structure										.	.	.	.	.	.	.									G	G	G			T	T																								T						B	T	T	T	B									T	T
Template Predicted Secondary structure										.	.	.	.	.	.	.
Template SS confidence
		163	.	.	.	.	.	.	170								.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.
		240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.				.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.		.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.
Predicted Secondary structure																																					.	.	.																					.
Query SS confidence																																					.	.	.																					.
Query Sequence		D	A	H	G	T	L	E	N	L	P	L	P	L	V	P	Q	P	N	A	A	T	A	L	A	A	L	R	A	S	G	L	E	V	S	E	.	.	.	N	A	I	R	D	G	I	A	S	A	I	L	P	G	R	F	Q	I	V	S	.	E	S	P	R	V	I	F	D	V	A	H	N	P	H	A	A	E	Y	L	T	G
Query Conservation																																					.	.	.																					.
Alig confidence																																					.	.	.																					.
Template Conservation
Template Sequence		C	G	E	N	T	F	E	D	L	V	L	T	M	N	G	P	H	Q	I	E	N	A	G	V	A	L	K	T	L	E	A	T	G	L	P	L	S	E	K	A	I	R	E	G	L	K	N	A	K	N	L	G	R	F	E	I	L	E	K	N	G	K	M	Y	I	L	D	G	A	H	N	P	H	G	A	E	S	L	V	R
Template Known Secondary structure			S	S	S								S	S		S	T																																			T	T	S	S						T	T										S
Template Predicted Secondary structure
Template SS confidence
		243	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.	.	.	.	.	.	320	.	.
		316	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.					.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.
Predicted Secondary structure																																																												.	.	.	.
Query SS confidence																																																												.	.	.	.
Query Sequence		R	M	K	A	L	P	K	N	G	R	V	L	A	V	I	G	M	L	H	D	K	D	I	A	G	T	L	A	W	L	K	S	V	V	D	D	W	Y	C	A	P	L	E	G	P	R	G	A	T	A	E	Q	L	L	E	H	L	G	.	.	.	.	N	G	K	S	F	D	S	V	A	Q	A	W	D	A	A	M	A	D
Query Conservation																																																												.	.	.	.
Alig confidence																																																												.	.	.	.																.	.	.
Template Conservation																																																																															.	.	.
Template Sequence		S	L	K	L	Y	F	N	G	E	P	L	S	L	V	I	G	I	L	D	D	K	N	R	E	D	I	L	R	K	Y	T	G	I	F	E	R	V	I	V	T	R	V	P	S	P	R	M	K	D	M	N	S	L	V	D	M	A	K	K	F	F	K	N	V	E	V	I	E	D	P	L	E	A	I	E	S	T	.	.	.
Template Known Secondary structure								T	T											T	T	S							G	G	G	T	T	T		S								S	S	T	T																S						S	S							T		.	.	.
Template Predicted Secondary structure																																																																															.	.	.
Template SS confidence
		323	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.
		392	.	.	.	.	.	.	.	400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		A	K	A	E	D	T	V	L	V	C	G	S	F	H	T	V	A	H	V	M	E	V	I	D	A	R	R	S
Query Conservation
Alig confidence		.	.	.
Template Conservation		.	.	.
Template Sequence		.	.	.	E	R	A	T	V	V	T	G	S	L	F	L	V	G	Y	V	R	E	F	L	T	T	G	K	I
Template Known Secondary structure		.	.	.		S						S															S	S
Template Predicted Secondary structure		.	.	.
Template SS confidence
					400	.	.	.	.	.	.	.	.	.	410	.	.	.	.	.	.	.	.	.	420	.	.	.	.