|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | Q | V | L | I | T | G | A | T | G | L | V | G | G | H | L | L | R | M | L | I | N | E | P | K | V | N | A | I | A | A | P | T | R | R | P | L | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | M | P | G | V | F | N | P | H | D | P | Q | L | S | D | A | L | A | Q | V | T | D | P |
Query Conservation |   |
  |
|
|
|
|
|
|
|
|
|   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |
|   |   |   |   |
|   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|
|
|
|   |
|
|
|   |
|   |
|   |   |
|   |   |   |
| . | . |
|   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
R | V | A | L | V | T | G | G | S | R | G | L | G | F | G | I | A | Q | G | L | A | E | A | G | . |
. |
C | S | V | V | V | A | S | R | N | L | E | E | A | S | E | A | A | Q | K | L | T | E | K | Y | G | V | E | T | M | A | F | R | C | D | V | S | N | Y | E | E | V | K | K | L | L | E | A | V | K | E | K | F | G | K |
Template Known Secondary structure |   |
|  |  |  |  |  | T | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|  |  |  |  |  |  | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
| . | . |
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
. | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . |
  |
  |   |
63 | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
Query Sequence |   |
I | D | I | V | F | C | C | L | G | T | T | R | R | E | A | G | S | K | E | A | F | I | H | A | D | Y | T | L | V | V | D | T | A | L | T | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | R | R | L | G | A | Q | H | M | L | V | V | S | A | M | G | A | N | A | H | S | P | F | F | Y | N | R | V | K | G | . |
. |
. |
. |
. |
Query Conservation |   |
  |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |
Template Sequence |   |
L | D | T | V | V | N | A | A | G | I | N | R | R | H | P | A | E | E | F | P | L | D | E | F | R | Q | V | I | E | V | N | L | F | G | T | Y | Y | V | C | R | E | A | F | S | L | L | R | E | S | D | N | P | S | I | I | N | I | G | S | L | T | V | E | E | V | T | M | P | N | I | S | A | Y | A | A | S | K | G | G | V |
Template Known Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|
|
|
|
| G | G | G |
|
|  |  |  |  |  |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S | S |
|  |  |  |  |  |
|
| G | G | G | T |
|
|
| S | S | S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
88 | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
128 | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | |
|
. | . | . | . | . | . | . | . | . | 200 | . |
Predicted Secondary structure |   |
. | . | . | . |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . | . |  |
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
E | M | E | E | A | L | I | A | Q | N | W | P | K | L | T | I | A | R | P | S | M | L | L | G | D | R | S | K | Q | R | M | N | E | T | L | F | A | P | L | F | R | L | L | P | G | N | W | K | S | I | D | A | R | D | V | A | R | V | M | L | A | E | S | . |
. |
M | R | P | E | H | E | G | V | T | I | L |
Query Conservation |   |
. | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|   |
|   |   |   | . | . |   |   |   |   |   |   |
|   |   |   |   |
Alig confidence |   |
. | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|
|
|   |   |
|   |
|
|   |
|   |   |   |   |   |
|
|
|   |   |
|   |
Template Sequence |   |
A | S | L | T | K | A | L | A | K | E | W | G | R | Y | G | I | R | V | N | V | I | A | P | G | W | Y | R | T | K | M | T | E | A | V | F | S | D | P | E | K | L | D | Y | M | L | K | R | I | P | L | G | R | T | G | V | P | E | D | L | K | G | V | A | V | F | L | A | S | E | E | A | K | Y | V | T | G | Q | I | I | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  | G | G | G | T |
|  |  |  |  |  |  |  |
|
| B |
| S | T | T | T |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  | T |
| T | T | S | S |
| B |
| G | G | G | G |  |  |  |  |  |  |  |  | S | G | G | G | T | T |
|
| S |
|  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|
|
|
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
168 | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . |
  |
  |   |
202 | . | . |
Predicted Secondary structure |   |
 |  |  |
Query SS confidence |   |
|
|
|
Query Sequence |   |
S | S | S |
Query Conservation |   |
  |   |   |
Alig confidence |   |
|
|
|
Template Conservation |   |
|
|
|
Template Sequence |   |
V | D | G |
Template Known Secondary structure |   |
 | S | T |
Template Predicted Secondary structure |   |
 |
|
|
Template SS confidence |   |
|
|
|
  |   |
248 | . | 250 |
  |