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Job DescriptionP45469
Confidence98.83%DateThu Jan 5 12:02:46 GMT 2012
Rank113Aligned Residues203
% Identity18%Templatec1fdvA_
PDB info PDB header:dehydrogenaseChain: A: PDB Molecule:17-beta-hydroxysteroid dehydrogenase; PDBTitle: human 17-beta-hydroxysteroid-dehydrogenase type 1 mutant2 h221l complexed with nad+
Resolution3.10 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   2.......10.........20....... ..30...... ...40.........50.........60......
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Query Sequence  SQVLITGATGLVGGHLLRMLINEPKV. NAIAAPTRR. . . . . . . . . . . . . . PLGDMPGVFNPHDPQLSDALAQVTDPIDIV
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Template Sequence  TVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQLDVRDSKSVAAARERVTEG
Template Known Secondary structure  S

SS
TT

SSGGG
TT

TTS

TT
T
TTS
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   3......10.........20.........30.........40.........50.........60.........70.........80..
 
   67..70....... ..80.........90.........100.........110.........120 .........
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Query Sequence  FCCLGTTRREA. . . . . . . . . . . . . . . GSKEAFIHADYTLVVDTALTGRRLGAQHMLVVSAMGANAHSPF. . FYNRVKGEM
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Template Sequence  RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFAL
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BS
GGGS
TT


GGGTS

TT
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   83......90.........100.........110.........120.........130.........140.........150.........160..
 
   130.... .....140.........150.........160.........170...... ...180........
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Query Sequence  EEALI. . . . . . AQNWPKLTIARPSMLLGDRSKQRMNETLFAPLFRLLPGNWKS. . . . . . . . . . . . . . . IDARDVARVMLA
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Template Sequence  EGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYLALSKQVFREAAQNPEEVAEVFLT
Template Known Secondary structure  GGGT
S
BSSSTTGGGB

S

B
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   163......170.........180.........190.........200.........210.........220.........230.........240..
 
   189190.........200....
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Query Sequence  ESMRPEHEGVTILSSS
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Template Sequence  ALRAPKPTLRYFTTER
Template Known Secondary structure 
SS

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ST
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   243......250........
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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