Job Description P22188 Confidence 24.46% Date Thu Jan 5 11:38:45 GMT 2012 Rank 411 Aligned Residues 68 % Identity 18% Template c3dg8B_ PDB info PDB header:oxidoreductase, transferase Chain: B: PDB Molecule:bifunctional dihydrofolate reductase-thymidylate PDBTitle: quadruple mutant (n51i+c59r+s108n+i164l) plasmodium2 falciparum dihydrofolate reductase-thymidylate synthase3 (pfdhfr-ts) complexed with rjf670, nadph, and dump Resolution 2.58 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		335	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350		.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.	.	.	.	.	.	380	.	.	.	.	.	.	.	.	.	390	.	.	.	.	.	.	.	.	.	400	.	.	.	.	.			.	.	.	.	410	.
Predicted Secondary structure																		.																																																								.	.
Query SS confidence																		.																																																								.	.
Query Sequence		R	L	Q	P	V	C	G	R	M	E	V	F	T	A	P	G	.	K	P	T	V	V	V	D	Y	A	H	T	P	D	A	L	E	K	A	L	Q	A	A	R	L	H	C	A	G	K	L	W	C	V	F	G	C	G	G	D	R	D	K	G	K	R	P	L	M	G	A	I	A	E	E	F	.	.	A	D	V	A	V	V
Query Conservation																		.																																																								.	.
Alig confidence																		.																																				.	.	.	.	.	.	.	.	.	.											.	.
Template Conservation																																																						.	.	.	.	.	.	.	.	.	.
Template Sequence		K	F	K	P	L	S	N	R	I	N	V	I	L	S	R	T	L	K	K	E	D	F	D	E	D	V	Y	I	I	N	K	V	E	D	L	I	V	L	L	G	K	L	N	Y	Y	K	C	F	I	L	G	G	.	.	.	.	.	.	.	.	.	.	S	V	V	Y	Q	E	F	L	E	K	K	L	I	K	K	I	Y	F
Template Known Secondary structure		T	T		S		T	T								S	S			T	T	T	S		S	S	S				S	S	T	T								T	S											.	.	.	.	.	.	.	.	.	.										T	T			S
Template Predicted Secondary structure																																																						.	.	.	.	.	.	.	.	.	.
Template SS confidence
		115	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.											.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.
		412
Predicted Secondary structure
Query SS confidence
Query Sequence		T
Query Conservation
Alig confidence
Template Conservation
Template Sequence		T
Template Known Secondary structure
Template Predicted Secondary structure
Template SS confidence
		185

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions