|   |
270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | |
. | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Y | G | Y | V | N | L | K | D | R | P | R | Q | P | V | Q | R | R | G | D | D | F | I | T | L | N | A | E | Q | A | M | Q | G | A | A | D | I | L | R | Q | S | K | K | . |
V | I | G | I | G | S | P | R | A | S | V | E | S | N | F | A | L | R | E | L | V | G | E | E | N | F | Y | T | G | I | A | H | G | E | Q | E | R |
Query Conservation |   |
  |   |   |   |   |   |
|   |
|
|   |   |
|
|   |
|   |   |
|   |   |   |   |
|
|
|
|
|
|
|   |   |
|
|
|
|
|   |   |   |   |   | . |   |   |
|   |   |
|   |   |   |
|   |
|   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|
|
|
|
|
|
|   |
|   |
|   |   |   |   |   |
|   |   |   |
|   |   |
|
|
|   |   |   |   |
|
|   |   |
|   |   |   |
|
|   |
Template Sequence |   |
L | T | A | D | Q | I | D | D | K | A | L | V | P | R | G | A | T | R | A | K | S | V | L | H | A | P | N | E | D | V | R | E | A | A | A | Q | L | V | A | A | K | N | P | V | I | L | A | G | G | G | V | A | R | S | G | G | S | E | A | L | L | K | L | A | E | M | V | G | V | P | V | V | T | T | S | T | G | A | G | V |
Template Known Secondary structure |   |
 |  |  |
|  |  |  |
| T | T | T | S |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
| S | S |  |  |  |  |  |
|  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
| T | T | T | T | T | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
166 | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . |
  |
  |   |
349 | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | |
|
|
. | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . | . | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  | . | . | . |  |  |
|
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | Q | L | A | L | K | V | L | R | E | G | G | I | Y | T | P | A | L | R | E | . |
. |
. |
I | E | S | Y | D | A | V | L | V | L | G | E | D | V | T | Q | T | G | A | R | V | A | L | A | V | R | Q | A | V | K | G | K | A | R | E | M | A | A | A | Q | K | V | A | D | W | Q | I | A | A | I | L | N | I | G | Q | R | A |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
| . | . | . |
|   |   |
|
|   |
|
|   |   |
|   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |
|   |   |   |
|   |
|   |
|
|
|
|
|
|   |   |   |   |
|   |   |
|
|   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . | . | . |   |   |   |   |   |   |   |
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Template Sequence |   |
F | P | E | T | H | A | L | A | M | G | S | A | G | F | C | G | W | K | S | A | N | D | M | M | A | A | A | D | F | V | L | V | L | G | S | R | L | S | D | W | G | I | A | Q | G | Y | . |
. |
. |
. |
. |
I | T | K | M | P | K | F | V | H | V | D | T | D | P | A | V | L | G | T | F | Y | F | P | L | L | S | V | V | A |
Template Known Secondary structure |   |
S |
| T | T | S | T | T |  |  |  |  |
| S | T | T | S |
|  |  |  |  |  |  |  |  |  |
| S |  |  |  |  |  | S |
|
|
|
| T | T | T | T | T | T | T | T | . | . | . | . | . | T |
|
|
|
| S |  |  |  |  |  | S |
| G | G | G | T | T | S | S | S |
|
| S |  |  |  |  |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
246 | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | |
|
|
|
|
. | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
426 | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | H | P | L | F | V | T | N | V | D | D | T | R | L | D | D | I | A | A | W | T | Y | R | A | P | V | E | D | Q | A | R | L | G | F | A | I | A | H | A | L | D | N | S | A | P | A | V | D | G | I | E | P | E | L | Q | S | K | I | D | V | I | V | Q | A | L | A | G | A | K | K | P | L | I | I | S | G | T | N | A | G |
Query Conservation |   |
|   |
|
|   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |   |
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |
|   |
|   |
Template Sequence |   |
D | A | K | T | F | M | E | Q | L | I | E | V | L | P | G | T | S | G | F | K | A | V | R | Y | Q | E | R | E | N | F | R | Q | A | T | E | F | R | A | A | W | D | G | W | V | R | E | Q | E | S | G | D | G | M | P | A | S | M | F | R | A | M | A | E | V | R | K | V | Q | R | P | E | D | I | I | V | T | D | I | G | N |
Template Known Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  | G | G | G | S | T | T |
|
|
|
|
| G | G | G | S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S |
|
|  |  |  |  |  |  |  |  |  |  | T |
|
| T | T |
|  |  |  |  |
| S | S | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
321 | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 |
  |
  |   |
506 | . | . | . | 510 | . | . | . | . | . | . | . | . | . | 520 | . | . | . | . | . | . | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
S | L | E | V | I | Q | A | A | A | N | V | A | K | A | L | K | G | R | G | A | D | V | G | I | T | M | I | A | R | S | V | N | S | M | G | L | G | I | M | G | G | G | S | L | E | E | A | L | T | E | L | E | T | G | R | A | D | A | V | V | V | L | E | N | D | L | H | R | H | A | S | A | I | R | V | N | A | A | L | A |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |
|   |
|
|
|
|   |
|   |
|
|
|
|   |   |   |
|   |   |   |   |   |   |
|
|
|   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|
|
|
|
|
|
|   |
|   |   |   |
|
|   |
|   |
|
|
|
|
|   |   |   |   |   |
|
|   |
|
|   |   |   |
Template Sequence |   |
H | T | L | P | M | F | G | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
A | I | L | Q | R | P | R | R | L | V | T | S | M | A | E | G | I | L | G | C | G | F | P | M | A | L | G | A | Q | L | A | E | P | N | S | R | V | F | L | G | T | G | D | G | A | L | Y | Y | H | F | N | E | F | R | V | A | V | E | H |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
| S | S | T | T |
|  |  | S |
| T | T | T |
|
| T | T |
|  |  |  |  |  |  |  |  |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  | G | G | G |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |
| . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
401 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
. | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . |
  |
  |   |
586 | . | . | . | 590 | . | . | . |
Predicted Secondary structure |   |
 |
|
|  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | P | L | V | M | V | V |
Query Conservation |   |
|
|   |
|
|
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|   |
|   |
|
|
|
Template Sequence |   |
K | L | P | V | I | T | M | V |
Template Known Secondary structure |   |
T |
|
|
|  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
  |   |
468 | . | 470 | . | . | . | . | . |
  |