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Job DescriptionP33602
Confidence100.00%DateThu Jan 5 11:52:24 GMT 2012
Rank2Aligned Residues683
% Identity15%Templatec1h0hA_
PDB info PDB header:dehydrogenaseChain: A: PDB Molecule:formate dehydrogenase (large subunit); PDBTitle: tungsten containing formate dehydrogenase from2 desulfovibrio gigas
Resolution1.8 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   215....220.........230.........240. ........250.........260.........270.........280......... 290
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Query Sequence  YNRKWDMQFAPSICQQCSIGCNISPGE. . RYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLKDRPRQPVQRRGDD. . F
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Template Conservation         
 
 
 
  
   

  
 
  





 
 
 
  
 
 
 

 

 
     
 
 

  



 

 
 
Template Sequence  ALKTVDAKQTTSVCCYCSVGCGLIVHTDKKTNRAINVEGDPDHPINEGSLCAKGASTWQLAENERRPANPLYRAPGSDQW
Template Known Secondary structure 

TTTTS
SSBTT


TTT


TT
TTTTT


TS
TTS
SS

TT
SS
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   4.....10.........20.........30.........40.........50.........60.........70.........80...
 
   291........300.........310.... .....320.........330......... 340.........350
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Query Sequence  ITLNAEQAMQGAADILRQSKKVIG. . . . . . . . . . . . . . . . . . IGSPRASVESNFALRELVGEENFYT. . GIAHGEQERLQ
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Template Conservation    







 

 

  
    
               
                       

               
Template Sequence  EEKSWDWMLDTIAERVAKTREATFVTKNAKGQVVNRCDGIASVGSAAMDNEECWIYQAWLRSLGLFYIEHQARIHSATVA
Template Known Secondary structure 


TTS

S

TTS
TTB


GGG

Template Predicted Secondary structure 


































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   84.....90.........100.........110.........120.........130.........140.........150.........160...
 
   351........360.........370.........380.........390.........400.........410.........420.........430
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Query Sequence  LALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALAVRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLF
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Template Conservation        .
         
   

 

  
 

  
 
        

  
 







 
 

  

 








 
Template Sequence  ALAESY. GRGAMTNHWIDLKNSDVILMMGSNPAENHPISFKWVMRAKDKGATLIHVDPRYTRTSTKCDLYAPLRSGSDIA
Template Known Secondary structure  .S

S
SS
TGGGGG
SS

STTTT

SS

TTGGG
S


TT
Template Predicted Secondary structure  .




























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   165....170 .........180.........190.........200.........210.........220.........230.........240...
 
   431........ 440.........450. ....
Predicted Secondary structure  .....




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Query Sequence  VTNVDDTRL. . . . . DDIAAWTYRAPV. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EDQA
Query Conservation 
       
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Template Conservation 
 


   

     
  

   

   

                                              
 
 
Template Sequence  FLNGMTKYILEKELYFKDYVVNYTNASFIVGEGFAFEEGLFAGYNKETRKYDKSKWGFERDENGNPKRDETLKHPRCVFQ
Template Known Secondary structure  TT
S
BGGGBBB
TT

TTTTTTTT
GGGG
B
B
TTS
B
B
TTS
STTB
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   244.....250.........260.........270.........280.........290.........300.........310.........320...
 
   456...460.........470.........480.........490.........500 .........510.........520...... ...
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Query Sequence  RLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIIS. . . . . GTNAGSLEVIQAAANVAKALKGRGAD. VGI
Query Conservation             
 
  
 

    
   
              
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Template Conservation   
      



 

 




   
  

   
          
    
     

    

   
  
 
 

 



 
Template Sequence  IMKKHYERYDLDKISAICGTPKELILKVYDAYCATGKPDKAGTIMYAMGWTQHTVGVQNIRAMSINQLLLGNIGVAGGGV
Template Known Secondary structure  TT




GGGSTT





SSTT
SSSTT
S
Template Predicted Secondary structure 




























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   324.....330.........340.........350.........360.........370.........380.........390.........400...
 
   530.........540.....
Predicted Secondary structure 














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Query Sequence  TMIARSVNSMGLGIMG. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Query Conservation         
  
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Template Conservation      
  
  
    
      
                                                         
Template Sequence  NALRGEANVQGSTDHGLLMHIYPGYLGTARASIPTYEEYTKKFTPVSKDPQSANWWSNFPKYSASYIKSMWPDADLNEAY
Template Known Secondary structure 

SBTTTT
BTTTTT

BTT

S





TT


GGGG
TTS
Template Predicted Secondary structure 




































































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   404.....410.........420.........430.........440.........450.........460.........470.........480...
 
   546...550.........560........ .570.........580.........590.........600....
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Query Sequence  . . . . . . . . . . GGSLEEALTELETGRADAVVVLE. NDLHRHASAIRVNAALAKAPLVMVVDHQRTAIMENA. . . . . . . . . .
Query Conservation  ..........
    
       
 



 
 
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Template Sequence  GYLPKGEDGKDYSWLTLFDDMFQGKIKGFFAWGQNPACSGANSNKTREALTKLDWMVNVNIFDNETGSFWRGPDMDPKKI
Template Known Secondary structure  S

B
TT


STT


S

SBSTT
SSS

TTTTGGGSTT

GGG
Template Predicted Secondary structure 









































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   484.....490.........500.........510.........520.........530.........540.........550.........560...
 
   605....610.........620.........630.........640.........650.........660
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Query Sequence  . . . HLVLSAASFAESDGTVINNEGRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLL. . . . . . . . . . . . . . . . . . . . .
Query Conservation  ...





    

 

  
 
 
 
    

 
    
      
  
   

  

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Template Sequence  KTEVFFLPCAVAIEKEGSISNSGRWMQWR. . . . . YVGPEPRKNAIPDGDLIVELAKRVQKLLAKTPGKLAAPVTKLKTDY
Template Known Secondary structure 

B

GGG


TT
.....

SS


TT
B
S
TT

S
GGG
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   564.....570.........580.........590.. .......600.........610.........620.........630........
 
   661........670.........680.........690.........700.........710.........720..
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Query Sequence  . SREVDWTQLDHVIDAVVAKIPELAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVH. . . . . . . . . . . . . . . . .
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Template Sequence  WVNDHGHFDPHKIAKLINGF. . ALKDFKVGDVEYKAGQQIATFGHLQADGSTTSGCWIYTGSYTEKGNMAARRDKTQTDM
Template Known Secondary structure  GB
TTS
B

B..BSS
TT
TT
B
S
GGG

TTS
B

SSGGGTTSTTGGG
B




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   639640.........650........ .660.........670.........680.........690.........700.........710......
 
   723......730.........740.........750.........760......
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Query Sequence  . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . EPRQPQDIDTMFTFSMEGNNQPTAHRSQVPFAWAPGWNSPQAWN
Query Conservation  ....................................                                            
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Template Conservation                
                                                              
  
Template Sequence  QAKIGLYPGWTWAWPVNRRIIYNRASVDLNGKPYAPEKAVVEWNAAEKKWVGDVPDGPWPPQADKEKGKRAFIMKPEGYA
Template Known Secondary structure  T

TTBSTTTT
SSTTGGGGB
TTS
BS
GGG
STTTTS

SS
S

TT
TTT


S
TTSSSS
B
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   717..720.........730.........740.........750.........760.........770.........780.........790......
 
   767..770.........780.........790.........800..... ....810.........820... ......830....
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Query Sequence  KFQDEVGGKLRFGDPGVRLFETSENGLDYFTSVPARFQP. . . . . . . . . . QDGKWRIAPYYHLFGSDE. . LSQRAPVFQSR
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Template Conservation              
    
                                 

  
 
 
     

   
 
   
   
Template Sequence  YLYGPGREDGPLPEYYEPMECPVIEHPFSKTLHNPTALHFATEEKAVCDPRYPFICSTYRVTEHWQTGLMTRNTPWLLEA
Template Known Secondary structure 
SS
TTSTT
SS






SSS



SS
S

S
TT

SS

SS




TTS


TT

TTSTS
Template Predicted Secondary structure 






























































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   797..800.........810.........820.........830.........840.........850.........860.........870......
 
   835....840.........850.........860.........870.........880.. .......890.........900.....
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Query Sequence  MPQPYIKLNPADAAKLGVNAGTRVSFSYDGNTVTLPVEIAEGLTAGQV. . . . . . . . GLPMGMSGIAPVLAGAHLEDLKE
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Template Conservation   
   
 


 

  



 

 
 
 
  
 
   
 

  
 

 
       
  
   
       
   
 

 
Template Sequence  EPQMFCEMSEELATLRGIKNGDKVILESVRGKLWAKAIITKRIKPFAIQGQQVHMVGIPWHYGWSFPKNGGDAANILTP
Template Known Secondary structure  S
S

T

TT
TT
TT


TT
S


TTSSTTS


GGGS

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   877..880.........890.........900.........910.........920.........930.........940.........950.....
 
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Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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