|   |
1 | . | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | |
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|  |  |
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
| . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
Query Sequence |   |
M | Q | Y | N | P | L | G | K | T | D | L | R | V | S | R | L | C | L | G | C | M | T | F | G | E | P | D | R | G | N | H | A | W | T | L | P | E | E | S | S | R | P | I | I | K | R | A | L | E | G | G | I | N | F | F | D | T | A | N | S | Y | S | D | G | S | S | E | E | I | V | G | R | A | L | R | D | F | . |
. |
. |
Query Conservation |   |
|   |
|
|   |
|
|   |
|
|
|   |
|
|   |
|
|   |
|
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|
|   |
|
|
|
|   |   |
|
|   |
|   |
|
|   |   |
|
|   |
|
|   |   |   | . | . | . |
Alig confidence |   |
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
Template Conservation |   |
|   |   |   |   |
| . |   |
|
|   |   |
|
|   |
|
|
|
|
|   |   |   | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |
|
|   |   |
|
|
|
|   |   |
|
| . | . | . |
|
|   |   |
|
|   |
|
|   |   |   |   |   |   |
Template Sequence |   |
I | T | F | F | K | L | . |
N | T | G | A | K | F | P | S | V | G | L | G | T | W | Q | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
S | P | G | L | V | G | D | A | V | A | A | A | V | K | I | G | Y | R | H | I | D | C | A | Q | I | Y | G | . |
. |
. |
N | E | K | E | I | G | A | V | L | K | K | L | F | E | D |
Template Known Secondary structure |   |
|
|  |  |  |
| . | T | T | S |
|  |  |  | S | B |
|  |  |
| T | T |
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |
|
| G | G | G | S | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
Template Predicted Secondary structure |   |
|  |  |  |  |
| . |
|
|
|
|  |  |
|  |  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
5 | . | . | . | . | 10 | |
. | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
130 | . | . | . | . | . | . | . | . | . | 140 | . |
Predicted Secondary structure |   |
. | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
A | R | R | E | D | V | V | V | A | T | K | V | F | H | R | V | G | D | L | P | E | G | L | S | R | A | Q | I | L | R | S | I | D | D | S | L | R | R | L | G | M | D | Y | V | D | I | L | Q | I | H | R | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | Y | N | T | P | I | E | E | T | L | E | A |
Query Conservation |   |
. | . |   |   |
|   |   |
|   |
|   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |
|
|
|   |   |
|
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |   |   |   |
|   |
|
|   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|   |
|
|   |
|
|   |   |
|   |
|
|
|   |   |
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
Template Sequence |   |
R | V | V | K | R | E | D | L | F | I | T | S | K | L | . |
. |
. |
. |
. |
. |
W | C | T | D | H | D | P | Q | D | V | P | E | A | L | N | R | T | L | K | D | L | Q | L | E | Y | V | D | L | Y | L | I | H | W | P | A | R | I | K | K | G | S | V | G | I | K | P | E | N | L | L | P | V | D | I | P | S | T | W | K | A |
Template Known Secondary structure |   |
T | S |
|
| G | G | G |
|  |  |  |  |  |  | . | . | . | . | . | . |
| G | G | G |
| S | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| S |
| B | S |  |  |  |  |
| S | S |
|  |  |
| S | S |
| S | S |
|
| G | G | G |  |  |
|
|
|  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
69 | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | |
|
|
|
|
|
. | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . |
  |
  |   |
142 | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | N | D | V | V | K | A | G | K | A | R | Y | I | G | A | S | S | M | H | A | S | Q | F | A | Q | A | L | E | L | Q | K | Q | H | G | W | A | Q | F | V | S | M | Q | D | H | Y | N | L | I | Y | R | E | E | E | R | E | M | L | P | L | C | Y | Q | E | G | V | A | V | I | P | W | S | P | L | A | R | G | R | L | T | R |
Query Conservation |   |
|   |   |
|   |   |   |
|   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |
|   |   |   |
|   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|
|   |   |
|   |
|   |   |
Template Sequence |   |
M | E | A | L | Y | D | S | G | K | A | R | A | I | G | V | S | N | F | S | T | K | K | L | A | D | L | L | E | L | A | . |
. |
. |
. |
R | V | P | P | A | V | N | Q | V | E | C | H | P | S | W | R | . |
. |
Q | T | K | L | Q | E | F | C | K | S | K | G | V | H | L | S | A | Y | S | P | L | G | S | P | G | T | T | W |
Template Known Secondary structure |   |
 |  |  |  |  |  | T | T | S | B | S | S |  |  |  |  | S |
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . | S | S |
|
| S |  |  |  |  |  |
| B | T | T | B |
| . | . |
|  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  | S | T | T |
|
| T | T |
| T | T |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
143 | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | |
|
|
|
. | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | |
|
. | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . |
  |
  |   |
222 | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
P | W | G | E | T | T | A | R | L | V | S | D | E | V | G | K | N | L | Y | K | E | S | D | E | N | D | A | Q | I | A | E | R | L | T | G | V | S | E | E | L | G | A | T | R | A | Q | V | A | L | A | W | L | L | S | K | P | G | I | A | A | P | I | I | G | T | S | R | E | E | Q | L | D | E | L | L | N | A | V | D | I |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |   |   |   |
|   |   |
|   |
|
|   |   |   |
|   |   |   |   |
|   |   |
|
|   |
|   |   |   |   |   |   |
|   |
|
|
|   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |
|   |   |
|
|   |   |   |
|   |
|   |
|
|   |
|
|   |
|   |
|   |   |   | . | . |   |   |
|
|   |
|   |   |   |   |
|   |
|   |
|
|   |   |
|   |   |   |
Template Sequence |   |
L | K | S | D | V | L | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
N | P | I | L | N | M | V | A | E | K | L | G | K | S | P | A | Q | V | A | L | R | W | G | L | Q | M | G | . |
. |
H | S | V | L | P | K | S | T | N | E | G | R | I | K | E | N | F | N | V | F | D | W |
Template Known Secondary structure |   |
S |
|
|
| G | G | G | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  | T |
|
|  |  |  |  |  |  |  |  |  |  |  | T | T | . | . |
|  |  |
|
| B |
| S |
|  |  |  |  |  |  |  |  |
|
| S | S |
|
Template Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |
|  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
217 | . | . | 220 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | |
|
. | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . |
  |
  |   |
302 | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
T | L | K | P | E | Q | I | A | E | L | E | T | P | Y | K | P | H | P | V | V | G |
Query Conservation |   |
  |
|   |   |
|   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
Template Sequence |   |
S | I | P | D | Y | M | F | A | K | F | A | E | I | E | Q | A | R | L | V | T | G |
Template Known Secondary structure |   |
|
|
|  |  |  |  |  |  | G | G | G | S |
|
|
|
| S |
|
|
|
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
273 | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . |
  |