Secondary structure and disorder prediction

		1	.	.	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60
Sequence		M	T	E	M	A	K	G	S	V	T	H	Q	R	L	I	A	L	L	S	Q	E	G	A	D	F	R	V	V	T	H	E	A	V	G	K	C	E	A	V	S	E	I	R	G	T	A	L	G	Q	G	A	K	A	L	V	C	K	V	K	G
Secondary structure
SS confidence
Disorder		?	?	?	?	?	?	?	?	?	?
Disorder confidence
		.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120
Sequence		N	G	V	N	Q	H	V	L	A	I	L	A	A	D	Q	Q	A	D	L	S	Q	L	A	S	H	I	G	G	L	R	A	S	L	A	S	P	A	E	V	D	E	L	T	G	C	V	F	G	A	I	P	P	F	S	F	H	P	K	L	K
Secondary structure
SS confidence
Disorder
Disorder confidence
		.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.
Sequence		L	V	A	D	P	L	L	F	E	R	F	D	E	I	A	F	N	A	G	M	L	D	K	S	V	I	L	K	T	A	D	Y	L	R	I	A	Q	P	E	L	V	N	F	R	R	T	A
Secondary structure
SS confidence
Disorder																																															?	?
Disorder confidence

Confidence Key
High(9)											Low (0)

?	Disordered
	Alpha helix
	Beta strand

Domain analysis

Hover over an aligned region to see model and summary info

Please note, only up to the top 20 hits are modelled to reduce computer load

Rank Aligned region

PDB 1vjf chain A Region: 10 - 165 Aligned: 152 Modelled: 156 Confidence: 100.0% Identity: 28% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 1vki chain A Region: 8 - 165 Aligned: 154 Modelled: 158 Confidence: 100.0% Identity: 23% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 2dxa chain A Region: 13 - 166 Aligned: 152 Modelled: 154 Confidence: 100.0% Identity: 23% PDB header:translation Chain: A: PDB Molecule:protein ybak; PDBTitle: crystal structure of trans editing enzyme prox from e.coli Phyre2 PDB 1wdv chain A Region: 12 - 165 Aligned: 149 Modelled: 151 Confidence: 100.0% Identity: 17% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 1dbx chain A Region: 13 - 165 Aligned: 150 Modelled: 152 Confidence: 100.0% Identity: 21% Fold: YbaK/ProRS associated domain Superfamily: YbaK/ProRS associated domain Family: YbaK/ProRS associated domain Phyre2 PDB 2cx5 chain B Region: 8 - 165 Aligned: 152 Modelled: 158 Confidence: 100.0% Identity: 23% PDB header:translation Chain: B: PDB Molecule:a putative trans-editing enzyme; PDBTitle: crystal structure of a putative trans-editing enzyme for2 prolyl trna synthetase Phyre2 PDB 3op6 chain B Region: 12 - 163 Aligned: 137 Modelled: 152 Confidence: 100.0% Identity: 23% PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an oligo-nucleotide binding protein (lpg1207)2 from legionella pneumophila subsp. pneumophila str. philadelphia 1 at3 2.00 a resolution Phyre2 PDB 3mem chain A Region: 32 - 166 Aligned: 130 Modelled: 134 Confidence: 100.0% Identity: 15% PDB header:signaling protein Chain: A: PDB Molecule:putative signal transduction protein; PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution Phyre2 PDB 2j3m chain A Region: 26 - 146 Aligned: 116 Modelled: 121 Confidence: 98.2% Identity: 16% PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol Phyre2 PDB 1t1v chain A Region: 12 - 56 Aligned: 45 Modelled: 45 Confidence: 56.8% Identity: 7% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: SH3BGR (SH3-binding, glutamic acid-rich protein-like) Phyre2 PDB 2ct6 chain A Region: 11 - 29 Aligned: 19 Modelled: 19 Confidence: 54.1% Identity: 21% PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain-binding glutamic acid-rich-like PDBTitle: solution structure of the sh3 domain-binding glutamic acid-2 rich-like protein 2 Phyre2 PDB 1u6t chain A Region: 11 - 29 Aligned: 19 Modelled: 19 Confidence: 47.7% Identity: 16% PDB header:protein binding, signaling protein Chain: A: PDB Molecule:sh3 domain-binding glutamic acid-rich-like PDBTitle: crystal structure of the human sh3 binding glutamic-rich2 protein like Phyre2 PDB 1h75 chain A Region: 12 - 46 Aligned: 35 Modelled: 35 Confidence: 41.4% Identity: 14% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1nm3 chain B Region: 12 - 46 Aligned: 35 Modelled: 35 Confidence: 40.8% Identity: 17% PDB header:electron transport Chain: B: PDB Molecule:protein hi0572; PDBTitle: crystal structure of heamophilus influenza hybrid-prx5 Phyre2 PDB 1nm3 chain A domain 1 Region: 12 - 46 Aligned: 35 Modelled: 35 Confidence: 39.7% Identity: 17% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 1r7h chain A Region: 12 - 46 Aligned: 35 Modelled: 35 Confidence: 38.5% Identity: 11% Fold: Thioredoxin fold Superfamily: Thioredoxin-like Family: Thioltransferase Phyre2 PDB 3nzn chain A Region: 12 - 56 Aligned: 45 Modelled: 45 Confidence: 36.6% Identity: 24% PDB header:oxidoreductase Chain: A: PDB Molecule:glutaredoxin; PDBTitle: the crystal structure of the glutaredoxin from methanosarcina mazei2 go1 Phyre2 PDB 2h31 chain A Region: 10 - 60 Aligned: 51 Modelled: 51 Confidence: 28.1% Identity: 14% PDB header:ligase, lyase Chain: A: PDB Molecule:multifunctional protein ade2; PDBTitle: crystal structure of human paics, a bifunctional carboxylase and2 synthetase in purine biosynthesis Phyre2 PDB 3lgc chain A Region: 12 - 31 Aligned: 20 Modelled: 20 Confidence: 24.0% Identity: 5% PDB header:unknown function Chain: A: PDB Molecule:glutaredoxin 1; PDBTitle: crystal structure of glutaredoxin 1 from francisella2 tularensis Phyre2 PDB 2klx chain A Region: 12 - 46 Aligned: 35 Modelled: 35 Confidence: 23.4% Identity: 20% PDB header:oxidoreductase Chain: A: PDB Molecule:glutaredoxin; PDBTitle: solution structure of glutaredoxin from bartonella henselae str.2 houston Phyre2 1 d1vjfa_ 2 d1vkia_ 3 c2dxaA_ 4 d1wdva_ 5 d1dbxa_ 6 c2cx5B_ 7 c3op6B_ 8 c3memA_ 9 c2j3mA_ 10 d1t1va_ 11 c2ct6A_ 12 c1u6tA_ 13 d1h75a_ 14 c1nm3B_ 15 d1nm3a1 16 d1r7ha_ 17 c3nznA_ 18 c2h31A_ 19 c3lgcA_ 20 c2klxA_ 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74

Detailed template information

# Template Alignment Coverage 3D Model Confidence % i.d. Template Information

1 d1vjfa_ 100.0 28 Fold:YbaK/ProRS associated domain Superfamily:YbaK/ProRS associated domain Family:YbaK/ProRS associated domain 2 d1vkia_ 100.0 23 Fold:YbaK/ProRS associated domain Superfamily:YbaK/ProRS associated domain Family:YbaK/ProRS associated domain 3 c2dxaA_ 100.0 23 PDB header:translation Chain: A: PDB Molecule:protein ybak; PDBTitle: crystal structure of trans editing enzyme prox from e.coli 4 d1wdva_ 100.0 17 Fold:YbaK/ProRS associated domain Superfamily:YbaK/ProRS associated domain Family:YbaK/ProRS associated domain 5 d1dbxa_ 100.0 21 Fold:YbaK/ProRS associated domain Superfamily:YbaK/ProRS associated domain Family:YbaK/ProRS associated domain 6 c2cx5B_ 100.0 23 PDB header:translation Chain: B: PDB Molecule:a putative trans-editing enzyme; PDBTitle: crystal structure of a putative trans-editing enzyme for2 prolyl trna synthetase 7 c3op6B_ 100.0 23 PDB header:unknown function Chain: B: PDB Molecule:uncharacterized protein; PDBTitle: crystal structure of an oligo-nucleotide binding protein (lpg1207)2 from legionella pneumophila subsp. pneumophila str. philadelphia 1 at3 2.00 a resolution 8 c3memA_ 100.0 15 PDB header:signaling protein Chain: A: PDB Molecule:putative signal transduction protein; PDBTitle: crystal structure of a putative signal transduction protein2 (maqu_0641) from marinobacter aquaeolei vt8 at 2.25 a resolution 9 c2j3mA_ 98.2 16 PDB header:ligase Chain: A: PDB Molecule:prolyl-trna synthetase; PDBTitle: prolyl-trna synthetase from enterococcus faecalis complexed2 with atp, manganese and prolinol 10 d1t1va_ 56.8 7 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:SH3BGR (SH3-binding, glutamic acid-rich protein-like) 11 c2ct6A_ 54.1 21 PDB header:structural genomics, unknown function Chain: A: PDB Molecule:sh3 domain-binding glutamic acid-rich-like PDBTitle: solution structure of the sh3 domain-binding glutamic acid-2 rich-like protein 2 12 c1u6tA_ 47.7 16 PDB header:protein binding, signaling protein Chain: A: PDB Molecule:sh3 domain-binding glutamic acid-rich-like PDBTitle: crystal structure of the human sh3 binding glutamic-rich2 protein like 13 d1h75a_ 41.4 14 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 14 c1nm3B_ 40.8 17 PDB header:electron transport Chain: B: PDB Molecule:protein hi0572; PDBTitle: crystal structure of heamophilus influenza hybrid-prx5 15 d1nm3a1 39.7 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 16 d1r7ha_ 38.5 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 17 c3nznA_ 36.6 24 PDB header:oxidoreductase Chain: A: PDB Molecule:glutaredoxin; PDBTitle: the crystal structure of the glutaredoxin from methanosarcina mazei2 go1 18 c2h31A_ 28.1 14 PDB header:ligase, lyase Chain: A: PDB Molecule:multifunctional protein ade2; PDBTitle: crystal structure of human paics, a bifunctional carboxylase and2 synthetase in purine biosynthesis 19 c3lgcA_ 24.0 5 PDB header:unknown function Chain: A: PDB Molecule:glutaredoxin 1; PDBTitle: crystal structure of glutaredoxin 1 from francisella2 tularensis 20 c2klxA_ 23.4 20 PDB header:oxidoreductase Chain: A: PDB Molecule:glutaredoxin; PDBTitle: solution structure of glutaredoxin from bartonella henselae str.2 houston 21 c3ic4A_ not modelled 19.7 39 PDB header:oxidoreductase Chain: A: PDB Molecule:glutaredoxin (grx-1); PDBTitle: the crystal structure of the glutaredoxin(grx-1) from archaeoglobus2 fulgidus 22 c3f0iA_ not modelled 17.5 25 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: arsenate reductase from vibrio cholerae. 23 d1pz4a_ not modelled 17.5 7 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 24 d1rw1a_ not modelled 16.9 10 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ArsC-like 25 c2kokA_ not modelled 16.8 17 PDB header:oxidoreductase Chain: A: PDB Molecule:arsenate reductase; PDBTitle: solution structure of an arsenate reductase (arsc) related protein2 from brucella melitensis. seattle structural genomics center for3 infectious disease target braba.00007.a. 26 c3gkxB_ not modelled 16.4 12 PDB header:structural genomics, unknown function Chain: B: PDB Molecule:putative arsc family related protein; PDBTitle: crystal structure of putative arsc family related protein from2 bacteroides fragilis 27 d1of5b_ not modelled 15.3 30 Fold:Cystatin-like Superfamily:NTF2-like Family:NTF2-like 28 d1fova_ not modelled 15.3 23 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 29 c3l78A_ not modelled 15.0 11 PDB header:transcription Chain: A: PDB Molecule:regulatory protein spx; PDBTitle: the crystal structure of smu.1142c from streptococcus mutans ua159 30 d1abaa_ not modelled 14.8 17 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 31 d1k0da2 not modelled 13.4 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 32 c2khpA_ not modelled 13.3 30 PDB header:electron transport Chain: A: PDB Molecule:glutaredoxin; PDBTitle: solution structure of glutaredoxin from brucella melitensis 33 d1o6xa_ not modelled 13.0 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 34 d1pbaa_ not modelled 11.9 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 35 d1dzfa2 not modelled 11.7 14 Fold:RPB5-like RNA polymerase subunit Superfamily:RPB5-like RNA polymerase subunit Family:RPB5 36 d1eika_ not modelled 11.7 14 Fold:RPB5-like RNA polymerase subunit Superfamily:RPB5-like RNA polymerase subunit Family:RPB5 37 d2obba1 not modelled 11.0 13 Fold:HAD-like Superfamily:HAD-like Family:BT0820-like 38 c2auwB_ not modelled 10.8 14 PDB header:unknown function Chain: B: PDB Molecule:hypothetical protein ne0471; PDBTitle: crystal structure of putative dna binding protein ne0471 from2 nitrosomonas europaea atcc 19718 39 d1z3ea1 not modelled 10.5 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ArsC-like 40 c3h8qB_ not modelled 10.5 25 PDB header:oxidoreductase Chain: B: PDB Molecule:thioredoxin reductase 3; PDBTitle: crystal structure of glutaredoxin domain of human thioredoxin2 reductase 3 41 d1jlva2 not modelled 10.5 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 42 c3bkrA_ not modelled 10.3 26 PDB header:lipid binding protein Chain: A: PDB Molecule:sterol carrier protein-2 like-3; PDBTitle: crystal structure of sterol carrier protein-2 like-3 (scp2-2 l3) from aedes aegypti 43 d1hmja_ not modelled 10.1 12 Fold:RPB5-like RNA polymerase subunit Superfamily:RPB5-like RNA polymerase subunit Family:RPB5 44 c3rdwB_ not modelled 9.8 22 PDB header:oxidoreductase Chain: B: PDB Molecule:putative arsenate reductase; PDBTitle: putative arsenate reductase from yersinia pestis 45 d2boaa2 not modelled 9.6 20 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 46 c3bn8A_ not modelled 9.5 9 PDB header:transport protein Chain: A: PDB Molecule:putative sterol carrier protein 2; PDBTitle: crystal structure of a putative sterol carrier protein type 2 (af1534)2 from archaeoglobus fulgidus dsm 4304 at 2.11 a resolution 47 d1axda2 not modelled 9.3 19 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 48 d1ayea2 not modelled 9.2 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 49 d1pyta_ not modelled 9.2 20 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 50 d1qcza_ not modelled 9.1 11 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 51 d1pcaa1 not modelled 9.0 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 52 c2ht9A_ not modelled 8.9 9 PDB header:oxidoreductase Chain: A: PDB Molecule:glutaredoxin-2; PDBTitle: the structure of dimeric human glutaredoxin 2 53 d1k0dd2 not modelled 8.7 13 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 54 d1jqga2 not modelled 8.7 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 55 c2e7pC_ not modelled 8.5 25 PDB header:electron transport Chain: C: PDB Molecule:glutaredoxin; PDBTitle: crystal structure of the holo form of glutaredoxin c1 from populus2 tremula x tremuloides 56 d1kwma2 not modelled 8.4 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 57 d1ljra2 not modelled 8.2 11 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 58 d1nsaa2 not modelled 8.0 15 Fold:Ferredoxin-like Superfamily:Protease propeptides/inhibitors Family:Pancreatic carboxypeptidase, activation domain 59 c2fw9A_ not modelled 8.0 16 PDB header:lyase Chain: A: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: structure of pure (n5-carboxyaminoimidazole ribonucleotide mutase)2 h59f from the acidophilic bacterium acetobacter aceti, at ph 8 60 d1u11a_ not modelled 7.9 16 Fold:Flavodoxin-like Superfamily:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) Family:N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) 61 c3fz4A_ not modelled 7.6 14 PDB header:oxidoreductase Chain: A: PDB Molecule:putative arsenate reductase; PDBTitle: the crystal structure of a possible arsenate reductase from2 streptococcus mutans ua159 62 d1z9ha2 not modelled 7.5 19 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 63 d1c44a_ not modelled 7.1 13 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 64 d1g7oa2 not modelled 6.8 0 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 65 c3trhI_ not modelled 6.7 16 PDB header:lyase Chain: I: PDB Molecule:phosphoribosylaminoimidazole carboxylase PDBTitle: structure of a phosphoribosylaminoimidazole carboxylase catalytic2 subunit (pure) from coxiella burnetii 66 d1gnwa2 not modelled 6.6 16 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 67 d1j9ba_ not modelled 6.6 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:ArsC-like 68 c3orsD_ not modelled 6.2 11 PDB header:isomerase,biosynthetic protein Chain: D: PDB Molecule:n5-carboxyaminoimidazole ribonucleotide mutase; PDBTitle: crystal structure of n5-carboxyaminoimidazole ribonucleotide mutase2 from staphylococcus aureus 69 d1r5aa2 not modelled 6.0 5 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 70 d1wika_ not modelled 6.0 7 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Thioltransferase 71 d1pn9a2 not modelled 5.7 9 Fold:Thioredoxin fold Superfamily:Thioredoxin-like Family:Glutathione S-transferase (GST), N-terminal domain 72 d2bvca1 not modelled 5.7 20 Fold:beta-Grasp (ubiquitin-like) Superfamily:Glutamine synthetase, N-terminal domain Family:Glutamine synthetase, N-terminal domain 73 d1ikta_ not modelled 5.3 25 Fold:SCP-like Superfamily:SCP-like Family:Sterol carrier protein, SCP 74 c1ykaA_ not modelled 5.2 22 PDB header:electron transport Chain: A: PDB Molecule:monothiol glutaredoxin ydhd; PDBTitle: solution structure of grx4, a monothiol glutaredoxin from2 e. coli.

Binding site prediction

Due to computational demand, binding site predictions are not run for batch jobs

If you want to predict binding sites, please manually submit your model of choice to 3DLigandSite

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
If you use the binding site predictions from 3DLigandSite, please also cite:
3DLigandSite: predicting ligand-binding sites using similar structures.
Wass MN, Kelley LA and Sternberg MJ Nucleic Acids Research 38, W469-73 (2010) [PubMed]
© Structural Bioinformatics Group Imperial College London Lawrence Kelley, Benjamin Jefferys Disclaimer Terms and Conditions	Component software Template detection: HHpred 1.51 Secondary structure prediction: Psi-pred 2.5 Disorder prediction: Disopred 2.4 Transmembrane prediction: Memsat_SVM Multi-template modelling and ab initio: Poing 1.0