|   |
1 | . | . | |
|
. | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | |
|
|
. | . | . | . | . | . | 40 | . |
Predicted Secondary structure |   |
|
|  | . | . |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |
|
|
|  |  |  |  |  |  |  |  | . | . | . |  |  |  |
|
|
|
|  |
Query SS confidence |   |
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
M | K | T | . |
. |
L | A | T | I | G | D | N | C | V | D | I | Y | P | Q | L | N | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
K | A | F | S | G | G | N | A | V | N | V | A | V | Y | . |
. |
. |
C | T | R | Y | G | I | Q | P |
Query Conservation |   |
|   |   | . | . |
|   |   |
|
|   |   |   |
|
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |
|
|   |   |   |
|   |
|   |   | . | . | . |
|   |   |
|
|   |   |
|
Alig confidence |   |
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|   |   |
|
|   |   |   |
|
|   |   |   |   |
|
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |
|
|   |   |
|
|   |
|
|   |   |   |
Template Sequence |   |
L | R | D | G | M | L | V | G | L | G | N | P | L | L | D | I | S | A | V | V | E | K | D | L | L | N | K | Y | D | M | Q | P | N | N | A | I | L | A | E | E | K | H | M | P | M | Y | Q | E | L | I | E | K | Y | Q | A | E | Y | I | A | G | G | S | V | Q | N | S | L | R | V | A | Q | W | I | L | Q | R | P | R | T | A |
Template Known Secondary structure |   |
|
| T | T |
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|  |  |  |  |  |  | T | T |
|
| S | S |
|  |  |  |
|
| G | G | G |  |  |  |  |  |  |  |  |  | T | S |
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |  |  |  |  |  |  | T |
| T | T | S |  |
Template Predicted Secondary structure |   |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
4 | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . |
  |
  |   |
42 | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | |
|
|
. | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | C | I | T | W | V | G | D | D | D | Y | G | T | K | L | K | Q | D | L | A | R | M | G | V | D | I | S | H | V | H | T | K | H | G | V | T | A | Q | T | Q | V | E | L | H | D | N | D | R | V | F | G | D | Y | T | E | G | . |
. |
. |
V | M | A | D | F | A | L | S | E | E | D | Y | A | W | L | A | Q | Y | D | I | V |
Query Conservation |   |
  |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Template Sequence |   |
I | F | F | G | C | V | G | Q | D | E | Y | A | R | I | L | E | E | R | A | T | S | N | G | V | N | V | Q | Y | Q | R | S | A | T | S | P | T | G | T | C | A | V | L | V | T | G | T | Q | R | S | L | C | A | N | L | A | A | A | N | D | F | T | P | E | H | L | R | S | D | G | N | R | A | Y | L | Q | G | A | Q | F | F |
Template Known Secondary structure |   |
 |  |  |  |  |  |  | S | S |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |  |  | S | S | S |
|
|
|  |  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
| G | G | G | G | G |
|
| G | G | G | G | G | S |  |  |  |  |  |  |  |  | T |
| S |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
84 | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . |
  |
  |   |
119 | 120 | . | |
|
|
|
|
|
. | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | |
|
|
|
. | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
. | . | . |
Predicted Secondary structure |   |
 |  |
| . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
| . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . |  |  |  |
Query SS confidence |   |
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
H | A | A | . |
. |
. |
. |
. |
. |
I | W | G | H | A | E | D | A | F | P | Q | L | H | A | A | G | K | L | T | A | F | D | F | S | D | K | W | . |
. |
. |
. |
D | S | P | L | W | Q | T | L | V | P | H | L | D | F | A | F | A | S | A | P | Q | E | D | E | T | L | R | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
L | K | M |
Query Conservation |   |
  |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . |   |   |   |
Alig confidence |   |
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
Y | V | S | G | F | F | F | T | V | S | F | E | S | A | L | S | V | A | K | E | A | A | A | T | G | R | M | F | M | M | N | L | S | A | P | F | V | P | Q | F | Y | K | N | N | L | E | E | I | F | P | Y | V | D | V | L | F | G | N | E | T | E | A | I | A | L | A | K | E | F | N | Y | G | T | E | D | L | R | E | I | G |
Template Known Secondary structure |   |
 |  |  | G | G | G |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T |
|  |  |  |  |  |
|
| S | T |  |  |  |  |  |
|  |  |  |  |  |  |  | G | G | G |
| S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
|
|  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
164 | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . |
  |
  |   |
179 | 180 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  | . | . | . | . | . | . |
|
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
K | A | I | V | A | R | . |
. |
. |
. |
. |
. |
G | A | G | T | V | I | V | T | L | G | E | N | G | S | I | A | W | D | G | A | Q | F | W | R | Q | A | P | E | P | V | T | V | I | D | T | M | G | A | G | D | S | F | I | A | G | F | L | C | G | W | S | A | G | M | T | L | P | Q | A | I | A | Q | G | T | A | C | A | A |
Query Conservation |   |
  |   |
|   |   |   | . | . | . | . | . | . |
|   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |   |   |
|   |   |   |
|
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |
|
|
|
|
|
|
|
|
|
|
|   |
|
|   |
|   |   |
|   |   |
|   |   |   |   |   |
|
|   |   |
|   |   |   |
|
|
Template Sequence |   |
K | R | I | A | A | L | P | K | E | N | G | K | R | K | R | I | V | I | I | T | Q | G | S | D | P | V | L | L | I | E | A | G | T | D | . |
. |
. |
N | V | R | E | F | P | V | Q | K | L | N | G | A | G | D | A | F | V | G | G | F | L | A | Q | L | L | Q | S | R | T | V | D | V | C | I | K | C | G | I | W | A | A | R |
Template Known Secondary structure |   |
 |  |  |  | T | S |
|
| S |
| T | T | S |
|
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  | T | T |
| S | . | . | . |
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|  |  | . | . | . |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
244 | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | |
|
|
. | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 |
  |
  |   |
253 | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
Query SS confidence |   |
|
|
|
|
Query Sequence |   |
K | T | I | Q |
Query Conservation |   |
  |   |
|   |
Alig confidence |   |
|
|
|
|
Template Conservation |   |
  |   |
|
|
Template Sequence |   |
E | I | I | Q |
Template Known Secondary structure |   |
 |  |  |
|
Template Predicted Secondary structure |   |
 |
|
|
|
Template SS confidence |   |
|
|
|
|
  |   |
329 | 330 | . | . |
  |