|   |
19 | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | |
|
. | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 70 | |
. | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
| . | . |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|  |  |  |  | . |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Query Sequence |   |
N | K | A | F | S | G | G | N | A | V | N | V | A | V | Y | C | T | R | Y | G | I | Q | . |
. |
P | G | C | I | T | W | V | G | D | D | D | Y | G | T | K | L | K | Q | D | L | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
R | M | G | V | D | I | S | H | V | . |
H | T | K | H | G |
Query Conservation |   |
  |   |   |   |   |
|
|   |   |   |
|   |
|   |   |
|   |   |
|
|   |   | . | . |
|   |   |   |   |   |
|
|   |
|   |   |
|   |   |
|   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|
|   |   |   |   |   | . |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|
|
|
|
|   |
|
|
|   |   |
|
|   |
|
|   |   |   |
|
|   |
|
|   |   |   |
|   | . |   |   |   |   |
|   |   |   |   |
|   |   |
|   |   |   |   |
|   |   |   |   |   |   |   |   |
|
|   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|   |   |
|
Template Sequence |   |
E | E | E | R | L | G | G | Q | A | G | I | I | A | N | T | L | A | G | L | K | I | R | K | V | I | A | Y | T | P | F | L | P | K | . |
R | L | A | E | L | F | K | K | G | V | L | Y | P | V | V | E | N | G | E | L | Q | F | K | P | I | Q | E | A | Y | R | E | G | D | P | L | K | I | N | R | I | F | E | F | R | K | G |
Template Known Secondary structure |   |
S |  |  |  |  |  | S |  |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
|
| S |
|
|
|  | . |  |  |  | T | T | S |
| T | T |  |  |  |  |  |  | S | S | S | S |  |  |  |  |  | G | G | G |
|
|
| T | T |
|
|
|
|  |  |  |  |  |  |  |
| T | T |
Template Predicted Secondary structure |   |
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|
|
|  | . |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | |
. | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
  |
  |   |
76 | . | . | . | |
|
|
80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | |
|
|
|
. | . | . | . | . | . | 120 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 130 | . |
Predicted Secondary structure |   |
|
|  |  | . | . | . |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
| . | . | . | . |
|
|
|  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |
Query SS confidence |   |
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
Query Sequence |   |
V | T | A | Q | . |
. |
. |
T | Q | V | E | L | H | D | N | D | R | V | F | G | D | Y | T | E | G | V | M | A | D | F | A | L | S | E | E | D | Y | A | W | L | A | . |
. |
. |
. |
Q | Y | D | I | V | H | A | A | I | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | H | A | E | D | A | F | P |
Query Conservation |   |
  |   |   |   | . | . | . |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
|   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |
|   |   |   |
|
|
|
|
|
|
|
|   |
|   |
|   |   |
|   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |   |
|
|
|
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |
Template Sequence |   |
L | K | F | K | L | G | D | E | T | I | E | I | P | N | S | G | R | F | I | V | S | A | R | F | E | S | I | S | R | I | E | T | R | E | D | I | K | P | F | L | G | E | I | G | K | E | V | D | G | A | I | F | S | G | Y | Q | G | L | R | T | K | Y | S | D | G | K | D | A | N | Y | Y | L | R | R | A | K | E | D | I | I |
Template Known Secondary structure |   |
|  |  |  | S | S | S |
|  |  |  |
|
| S |
|  |  |  |  |  |  |  |
|
| S | G | G | G |
|
| S |
|
| T | T | T | G | G | G |  |  |  |  |  |  |  |
| S |  |  |  |  |
|
| G | G | G |
|
| S | B |
| T | T | S |
| B |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
  |
  |   |
132 | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | |
|
|
|
. | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 180 | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  | . | . | . | . |  |  |  |
|
|  |  |  |  |
|
|
|
|  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
Q | L | H | A | A | G | K | L | T | A | F | D | F | S | D | K | W | D | S | P | L | W | Q | T | L | . |
. |
. |
. |
V | P | H | L | D | F | A | F | A | S | A | P | Q | E | D | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | T | L | R | L | K | M | K | A | I | V | A | R | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |
|
|   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |
|
|
|
|
|
|
|
|
|
|
|   |   |
|   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
E | F | K | E | K | D | V | K | I | H | V | E | F | A | S | V | Q | D | R | K | L | R | K | K | I | I | T | N | I | L | P | F | V | D | S | V | G | I | D | E | A | E | I | A | Q | I | L | S | V | L | G | Y | R | E | L | A | D | R | I | F | T | Y | N | R | L | E | D | S | I | L | G | G | M | I | I | L | D | E | L | N |
Template Known Secondary structure |   |
 |  |  |  | T | T |
|  |  |  |  |  |
|
|
|
| S |
|  |  |  |  |  |  |  |  |  |  | T | G | G | G | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | . |
  |
  |   |
186 | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
A | G | T | V | I | V | T | L | G | E | N | G | S | I | A | W | D | G | A | Q | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |
|
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
|   |
|
|
|
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
F | E | I | L | Q | V | H | T | T | Y | Y | L | M | Y | I | T | H | R | D | N | P | L | S | E | E | E | L | A | K | S | L | E | F | G | T | T | L | A | A | A | R | A | S | L | G | D | I | R | G | P | D | D | Y | K | V | G | L | K | V | P | F | N | E | R | S | E | Y | V | K | L | R | F | E | E | A | K | S | R | L | R |
Template Known Secondary structure |   |
| S |  |  |  |  |  |
| S | S |  |  |  |  |  |  |  | T | T |
| S | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S | S |
|
| S | G | G | G |  |  |  |  |  | T | S |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | S |
|
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
329 | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 | . | . | . | . | . | . | . | . | . | 390 | . | . | . | . | . | . | . | . | . | 400 | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
|
|
206 | . | . | . | 210 | . | . | . | . | |
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . |
Predicted Secondary structure |   |
. | . | . | . | . |  |  |  |  |
|
|
|
|
| . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Query SS confidence |   |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
. |
. |
F | W | R | Q | A | P | E | P | V | . |
T | V | I | D | T | M | G | A | G | D | S | F | I | A | G | F | L | C | G | W | S | A |
Query Conservation |   |
. | . | . | . | . |   |   |   |   |   |   |   |   |   | . |   |
|
|
|
|
|
|
|
|
|   |
|   |
|
|   |
|   |   |
|   |   |
Alig confidence |   |
. | . | . | . | . |
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |
|   |
|
|
|   |   |
|   |   |
|
|
|
|
|
|   |
|
|
|
|   |
|
|   |   |
|   |
Template Sequence |   |
M | R | E | Y | K | V | V | V | I | P | T | R | L | V | Q | N | P | V | L | T | V | G | L | G | D | T | I | S | A | G | A | F | L | T | Y | L | E |
Template Known Secondary structure |   |
| T | T |  |  |  |  |  |  |  |
|
|
|
| S | S |
| S |
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
409 | 410 | . | . | . | . | . | . | . | . | . | 420 | . | . | . | . | . | . | . | . | . | 430 | . | . | . | . | . | . | . | . | . | 440 | . | . | . | . | . |
  |