|   |
25 | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|  |  |  |  |
|
|  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | N | L | T | I | P | Q | G | Q | M | V | T | L | L | G | P | S | G | C | G | K | T | T | I | L | R | L | V | A | G | L | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
E | K | P | S | E | G | Q | I | F | I | D | G | E | D | V | T | H | R | S | I | Q | Q | R |
Query Conservation |   |
|
|
|   |
|   |   |
|
|
|   |   |
|   |
|   |
|
|
|
|
|
|
|
|
|   |   |
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |
|   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|
|
|
|
|
|   |
|
|
|   |   |
|   |
|
|   |
|   |
|
|
|   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |
|   |   |   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |
Template Sequence |   |
G | A | G | G | L | P | M | G | R | I | V | E | I | Y | G | P | E | S | S | G | K | T | T | L | T | L | Q | V | I | A | A | A | Q | R | E | G | K | T | C | A | F | I | D | A | E | H | A | L | D | P | I | Y | A | R | K | L | G | V | D | I | D | N | L | L | C | S | Q | P | D | T | G | E | Q | A | L | E | I | C | D | A |
Template Known Secondary structure |   |
S | S | S | S |  |  | T | T | S |  |  |  |  |  |
| S | T | T | S | S |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|
|
|  |  |  |  | S | S |
|
|
|
|  |  |  |  |  |  |  | T |
|
| G | G | G |
|  |  |  |
|
| S |
|  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1052 | . | . | . | . | . | . | . | 1060 | . | . | . | . | . | . | . | . | . | 1070 | . | . | . | . | . | . | . | . | . | 1080 | . | . | . | . | . | . | . | . | . | 1090 | . | . | . | . | . | . | . | . | . | 1100 | . | . | . | . | . | . | . | . | . | 1110 | . | . | . | . | . | . | . | . | . | 1120 | . | . | . | . | . | . | . | . | . | 1130 | . |
  |
  |   |
79 | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
D | I | C | M | V | F | Q | S | Y | A | L | F | P | H | M | S | L | G | E | N | V | G | Y | G | L | K | M | L | G | V | P | R | A | E | L | K | A | R | V | K | E | A | L | A | M | V | D | L | E | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | F | E | D | R | F | V | D | Q | I | S | G | G |
Query Conservation |   |
  |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |
|
|
|   |
|
|   |
|   |
|   |   |   |
|
|
|
|
|
Template Sequence |   |
L | A | R | S | G | A | V | D | V | I | V | V | D | S | V | A | A | L | T | P | K | A | E | I | E | G | L | A | A | R | M | M | S | Q | A | M | R | K | L | A | G | N | L | K | Q | S | N | T | L | L | I | F | I | N | Q | G | G | N | A | L | K | F | Y | A | S | V | R | L | D | I | R | R | I | G | A | V | K | E | G | E |
Template Known Secondary structure |   |
 |  | T | T | S | S |
|
|  |  |  |  |  |
| G | G | G |
|
|
|  |  |  |  |
|
|
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T |
|  |  |  |  |  |  |
|
|
| T | T |  |  |  |  |
| S |  |  |  |  |  |
|
|
|
|
|
|  |  | T | T |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1132 | . | . | . | . | . | . | . | 1140 | . | . | . | . | . | . | . | . | . | 1150 | . | . | . | . | . | . | . | . | . | 1160 | . | . | . | . | . | . | . | . | . | 1170 | . | . | . | . | . | . | . | . | . | 1180 | . | . | . | . | . | . | . | . | . | 1190 | . | . | . | . | . | . | . | . | . | 1200 | . | . | . | . | . | . | . | . | . | 1210 | . |
  |
  |   |
141 | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | |
|
. | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
210 | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |
|
|
| . | . |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|  |  |  |  | . | . | . | . | . | . |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
Query Sequence |   |
Q | Q | Q | R | V | A | L | A | R | A | L | I | L | K | P | . |
. |
K | V | L | L | F | D | E | P | L | S | N | L | D | A | N | L | R | R | S | M | R | D | K | I | R | E | L | Q | K | Q | F | D | I | T | S | L | Y | V | T | H | D | Q | S | E | A | F | A | V | S | D | T | V | L | V | . |
. |
. |
. |
. |
. |
M | N | K |
Query Conservation |   |
|   |
|
|
|   |
|
|
|
|
|   |   |   |
| . | . |   |
|
|
|
|
|
|
|
|
|   |
|
|   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |
|   |
|
|
|   |
|
|
|   |   |   |
|   |   |   |   |
|
|
|
|   |
| . | . | . | . | . | . |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
Template Conservation |   |
|   |
|
|
|
|
|
|   |
|
|
|
|   |
|   |
|   |
|
|
|
|
|
|
|
|
| . |
|
|   |
|
|   |   |   |
|   |   |   |   | . | . | . | . | . |   |   |
|   |   |
|
|
|
|
|
|
|   |   |   |   | . |   |   |
|
|   |
|
|
|   |
|
|
|
|
|   |   |
|
Template Sequence |   |
N | V | V | G | S | E | T | R | V | K | V | V | K | N | K | I | A | A | P | F | K | Q | A | E | F | Q | I | . |
L | Y | G | E | G | I | N | F | Y | G | E | L | V | . |
. |
. |
. |
. |
D | L | G | V | K | E | K | L | I | E | K | A | G | A | W | Y | . |
S | Y | K | G | E | K | I | G | Q | G | K | A | N | A | T | A | W |
Template Known Secondary structure |   |
 |  |
|  |  |  |  |  |  |  |  |  |  |  | S | S | S |
| T | T |
|  |  |  |  |  |  | . |  | T | T | T |  |  |
|  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |  | T | T | S | S |  |  |  | T | T |  |  | . |  |  | T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|  | . |  |
|
|
|
|
|  |  |  |  |  |  |  | . | . | . | . | . |  |  |  |  |
|
|  |  |  |  |
|
|  |  |  |  | . |  |  |
|
|  |  |  |  |
|
|  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1236 | . | . | . | 1240 | . | . | . | . | . | . | . | . | . | 1250 | . | . | . | . | . | . | . | . | . | 1260 | . | . | |
. | . | . | . | . | . | . | 1270 | . | . | . | . | . | |
|
|
|
|
. | . | . | . | 1280 | . | . | . | . | . | . | . | . | . | 1290 | . | |
. | . | . | . | . | . | . | . | 1300 | . | . | . | . | . | . | . | . |
  |
  |   |
213 | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|  |  |  |  |  |
|
|  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | H | I | M | Q | I | G | S | P | Q | D | L | Y | R | Q | P |
Query Conservation |   |
|   |
|
|   |   |
|   |   |   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | K | D | N | P | E | T | A | K | E | I | E | K | K | V | R |
Template Known Secondary structure |   |
 | T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
1309 | 1310 | . | . | . | . | . | . | . | . | . | 1320 | . | . | . | . |
  |