Job Description P75828 Confidence 99.11% Date Wed Jan 25 15:21:03 GMT 2012 Rank 34 Aligned Residues 196 % Identity 19% Template c3g5uB_ PDB info PDB header:membrane protein Chain: B: PDB Molecule:multidrug resistance protein 1a; PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding Resolution 3.80 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		14	.	.	.	.	.	20	.	.	.			.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure												.	.
Query SS confidence												.	.
Query Sequence		I	N	R	L	S	L	M	L	E	Q	.	.	N	N	V	L	I	G	E	N	A	W	G	K	S	S	L	L	D	A	L	T	L	L	L	S	P	E	S	D	L	Y	H	F	E	R	D	D	F	W	F	P	P	G	D	I	N	G	R	E	H	H	L	H	I	I	L	T	F	R	E	S	L	P	G	R	H	R	V	R
Query Conservation												.	.
Alig confidence												.	.																																														.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	Q	G	L	S	L	E	V	K	K	G	Q	T	L	A	L	V	G	S	S	G	C	G	K	S	T	V	V	Q	L	L	E	R	F	Y	D	P	M	A	G	S	V	F	L	D	G	K	E	I	K	Q	L	N	V	Q	W	L	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure				S							S	S	S							S	S	S	T	T									T	T	S	S			S						S	S	S	S		B	T	S	S						.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																											.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1049	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.	.	.	.	.
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	R	P	L	E	A	C	W	T	P	C	T	D	G	Y	H	R	I	F	Y	R	L	E	G	E	S	A	E	D	G	S	V	M	T	L	R	S	F	L	D	K	D	G	H	P	I	D	V	E	D	I	N	D	Q	A	R	H	L	V	R	L	M	P	V	L	R	L	R	D	A	R	F	M	R	R	I	R	N	G
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	A	Q	L	G	I	V	S	Q	E	P	I	L	F	D	C	S	I	A	E	N	I	A	Y	G	D	N	S	R	V	V	S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	T	T	S						S	S					S	S	B						T				S	S					.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																	1106	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.	.	.	.	.	.	.	.	.	1130	.	.	.	.	.	.	.
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	P	N	V	P	N	V	E	V	T	A	R	Q	L	D	F	L	A	R	E	L	S	S	H	P	Q	N	L	S	D	G	Q	I	R	Q	G	L	S	A	M	V	Q	L	L	E	H	Y	F	S	E	Q	G	A	G	Q	A	R	Y	R	L	M	R	R	R	A	S	N	E	Q	R	S	W	R	Y	L	D	I	I	N
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	Y	E	E	I	V	R	A	A	K	E	A	N	I	H	Q	F	I	D	S	L	P	D	K	Y	N
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.												T						S	S	T	T	T	G	G	G
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
																																																									1138	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.
		252	.	.	.	.	.	.			.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.			.	.	.	.	.	320	.	.	.	.	.	.	.
Predicted Secondary structure									.	.																																																									.	.
Query SS confidence									.	.																																																									.	.
Query Sequence		R	M	I	D	R	P	G	.	.	G	R	S	Y	R	V	I	L	L	G	L	F	A	T	L	L	Q	A	K	G	T	L	R	L	D	K	D	A	R	P	L	L	L	I	E	D	P	E	T	R	L	H	P	I	M	L	S	V	A	W	H	L	L	N	L	L	.	.	P	L	Q	R	I	A	T	T	N	S	G	E	L
Query Conservation									.	.																																																									.	.
Alig confidence									.	.																	.	.	.	.	.	.	.	.	.	.																															.	.
Template Conservation																											.	.	.	.	.	.	.	.	.	.
Template Sequence		T	R	V	G	D	K	G	T	Q	L	S	G	G	Q	K	Q	R	I	A	I	A	R	A	L	V	.	.	.	.	.	.	.	.	.	.	R	Q	P	H	I	L	L	L	D	E	A	T	S	A	L	D	T	E	S	E	K	V	V	Q	E	A	L	D	K	A	R	E	G	R	T	C	I	V	I	A	H	R	L	S	T
Template Known Secondary structure			B		S	T	T	S		S	S																.	.	.	.	.	.	.	.	.	.				S	S					S		S	S	S																	S	S	S	S							S		T	T	G
Template Predicted Secondary structure																											.	.	.	.	.	.	.	.	.	.
Template SS confidence
		1163	.	.	.	.	.	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.											.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.	.	1220	.	.	.	.	.	.	.	.	.	1230	.	.
		328	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		L	S	L	T	P	V	E	H	V	C	R	L	V	R	E	S	S	R	V	A	A	W
Query Conservation
Alig confidence							.	.	.	.
Template Conservation							.	.	.	.
Template Sequence		I	Q	N	A	D	.	.	.	.	L	I	V	V	I	Q	N	G	K	V	K	E	H
Template Known Secondary structure		G	G	S		S	.	.	.	.							T	B
Template Predicted Secondary structure							.	.	.	.
Template SS confidence
		1233	.	.	.	.					.	.	1240	.	.	.	.	.	.	.	.	.	1250

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions