Job Description P75828 Confidence 98.97% Date Wed Jan 25 15:21:03 GMT 2012 Rank 55 Aligned Residues 181 % Identity 21% Template c2pzfB_ PDB info PDB header:hydrolase Chain: B: PDB Molecule:cystic fibrosis transmembrane conductance regulator; PDBTitle: minimal human cftr first nucleotide binding domain as a head-to-tail2 dimer with delta f508 Resolution 2.00 Å

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		14	.	.	.	.	.	20	.	.	.			.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.
Predicted Secondary structure												.	.
Query SS confidence												.	.
Query Sequence		I	N	R	L	S	L	M	L	E	Q	.	.	N	N	V	L	I	G	E	N	A	W	G	K	S	S	L	L	D	A	L	T	L	L	L	S	P	E	S	D	L	Y	H	F	E	R	D	D	F	W	F	P	P	G	D	I	N	G	R	E	H	H	L	H	I	I	L	T	F	R	E	S	L	P	G	R	H	R	V	R
Query Conservation												.	.
Alig confidence												.	.																																			.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		L	K	D	I	N	F	K	I	E	R	G	Q	L	L	A	V	A	G	S	T	G	A	G	K	T	S	L	L	M	M	I	M	G	E	L	E	P	S	E	G	K	I	K	H	S	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure											T	T								S	T	T	S	S									T	T	S	S			S								S	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure																																																.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		441	.	.	.	.	.	.	.	.	450	.	.	.	.	.	.	.	.	.	460	.	.	.	.	.	.	.	.	.	470	.	.	.	.	.	.	.	.	.	480	.	.	.	.	.	.
		92	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.
Predicted Secondary structure
Query SS confidence
Query Sequence		R	Y	R	P	L	E	A	C	W	T	P	C	T	D	G	Y	H	R	I	F	Y	R	L	E	G	E	S	A	E	D	G	S	V	M	T	L	R	S	F	L	D	K	D	G	H	P	I	D	V	E	D	I	N	D	Q	A	R	H	L	V	R	L	M	P	V	L	R	L	R	D	A	R	F	M	R	R	I	R	N	G
Query Conservation
Alig confidence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																												.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																												.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	R	I	S	F	C	S	Q	F	S	W	I	M	P	G	T	I	K	E	N	I	I	G	V	S	Y	D	E	Y	R	Y	R	S	V	I	K	A	C	Q	L	E	E	D	I	S	K	F	A	E	K	D	N	I	V	L	G	E	G	G	I	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.							T	T					S									T	T														T	T						T	T	S	T	T	G	G	G					T	T		T	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.																																																												.	.	.	.
Template SS confidence
																			487	.	.	490	.	.	.	.	.	.	.	.	.	500	.	.	.	.	.	.	.	.	.	510	.	.	.	.	.	.	.	.	.	520	.	.	.	.	.	.	.	.	.	530	.	.	.	.	.	.	.	.	.	540	.	.	.	.	.
		172	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.
Predicted Secondary structure
Query SS confidence
Query Sequence		T	V	P	N	V	P	N	V	E	V	T	A	R	Q	L	D	F	L	A	R	E	L	S	S	H	P	Q	N	L	S	D	G	Q	I	R	Q	G	L	S	A	M	V	Q	L	L	E	H	Y	F	S	E	Q	G	A	G	Q	A	R	Y	R	L	M	R	R	R	A	S	N	E	Q	R	S	W	R	Y	L	D	I	I	N
Query Conservation
Template Conservation		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Known Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Predicted Secondary structure		.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
		252	.	.	.	.	.	.	.	260	.	.	.	.	.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.	.				.	.	.	.	.	320	.	.	.	.	.	.	.	.
Predicted Secondary structure																																																																	.	.	.
Query SS confidence																																																																	.	.	.
Query Sequence		R	M	I	D	R	P	G	G	R	S	Y	R	V	I	L	L	G	L	F	A	T	L	L	Q	A	K	G	T	L	R	L	D	K	D	A	R	P	L	L	L	I	E	D	P	E	T	R	L	H	P	I	M	L	S	V	A	W	H	L	L	N	L	L	.	.	.	P	L	Q	R	I	A	T	T	N	S	G	E	L	L
Query Conservation																																																																	.	.	.
Alig confidence		.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.																															.	.	.
Template Conservation		.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Template Sequence		.	.	.	.	T	L	S	G	G	Q	R	A	R	I	S	L	A	R	A	V	Y	.	.	.	.	.	.	.	.	.	.	.	.	K	D	A	D	L	Y	L	L	D	S	P	F	G	Y	L	D	V	L	T	E	K	E	I	F	E	S	C	V	C	K	L	M	A	N	K	T	R	I	L	V	T	S	K	M	E	H	L
Template Known Secondary structure		.	.	.	.	T	S																.	.	.	.	.	.	.	.	.	.	.	.	S			S						S	T	T	T	T	S																	T	T	T	S
Template Predicted Secondary structure		.	.	.	.																		.	.	.	.	.	.	.	.	.	.	.	.
Template SS confidence
						547	.	.	550	.	.	.	.	.	.	.	.	.	560	.	.	.													.	.	.	.	.	.	570	.	.	.	.	.	.	.	.	.	580	.	.	.	.	.	.	.	.	.	590	.	.	.	.	.	.	.	.	.	600	.	.	.	.	.	.	.	.	.	610
		329	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		S	L	T	P	V	E	H	V	C	R	L	V	R	E	S	S	R	V	A	A	W
Query Conservation
Alig confidence					.	.								.	.
Template Conservation					.	.								.	.
Template Sequence		K	K	A	.	.	D	K	I	L	I	L	H	.	.	E	G	S	S	Y	F	Y
Template Known Secondary structure					.	.	S							.	.	T	T
Template Predicted Secondary structure					.	.								.	.
Template SS confidence
		611	.	.			.	.	.	.	.	.	620			.	.	.	.	.	.	.

No model constructed - rank, confidence too low

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions