Job Description P07109 Confidence 100.00% Date Thu Jan 5 11:00:09 GMT 2012 Rank 20 Aligned Residues 231 % Identity 31% Template c3g5uB_ PDB info PDB header:membrane protein Chain: B: PDB Molecule:multidrug resistance protein 1a; PDBTitle: structure of p-glycoprotein reveals a molecular basis for2 poly-specific drug binding Resolution 3.80 Å

Show / Hide SS confidence

Show / Hide Conservation and Alignment quality

		2	.	.	.	.	.	.	.	10	.	.	.	.	.				.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.	.	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70	.	.	.	.	.	.	.	.
Predicted Secondary structure																.	.	.
Query SS confidence																.	.	.
Query Sequence		S	E	N	K	L	N	V	I	D	L	H	K	R	Y	.	.	.	G	E	H	E	V	L	K	G	V	S	L	Q	A	N	A	G	D	V	I	S	I	I	G	S	S	G	S	G	K	S	T	F	L	R	C	I	N	F	L	E	K	P	S	E	G	S	I	V	V	N	G	Q	T	I	N	L	V	R	D	K	D	G	Q
Query Conservation																.	.	.
Alig confidence																.	.	.																																																											.	.	.	.	.
Template Conservation																																																																													.	.	.	.	.
Template Sequence		L	E	G	N	V	Q	F	S	G	V	V	F	N	Y	P	T	R	P	S	I	P	V	L	Q	G	L	S	L	E	V	K	K	G	Q	T	L	A	L	V	G	S	S	G	C	G	K	S	T	V	V	Q	L	L	E	R	F	Y	D	P	M	A	G	S	V	F	L	D	G	K	E	I	K	Q	L	N	.	.	.	.	.
Template Known Secondary structure																S		G	G	G			S			S							S	S	S							S	S	S	T	T									T	T	S	S			S						S	S	S	S		B	T	S	S		.	.	.	.	.
Template Predicted Secondary structure																																																																													.	.	.	.	.
Template SS confidence
		1027	.	.	1030	.	.	.	.	.	.	.	.	.	1040	.	.	.	.	.	.	.	.	.	1050	.	.	.	.	.	.	.	.	.	1060	.	.	.	.	.	.	.	.	.	1070	.	.	.	.	.	.	.	.	.	1080	.	.	.	.	.	.	.	.	.	1090	.	.	.	.	.	.	.	.	.	1100	.
		79	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.											.	.	.
Predicted Secondary structure																																																																					.	.	.	.	.	.	.	.	.	.
Query SS confidence																																																																					.	.	.	.	.	.	.	.	.	.
Query Sequence		L	K	V	A	D	K	N	Q	L	R	L	L	R	T	R	L	T	M	V	F	Q	H	F	N	L	W	S	H	M	T	V	L	E	N	V	M	E	A	P	I	Q	V	L	G	L	S	K	Q	E	A	R	E	R	A	V	K	Y	L	A	K	V	G	I	D	E	R	A	.	.	.	.	.	.	.	.	.	.	Q	G	K
Query Conservation																																																																					.	.	.	.	.	.	.	.	.	.
Alig confidence		.	.	.	.	.	.	.	.																					.												.	.	.	.	.																							.	.	.	.	.	.	.	.	.	.
Template Conservation		.	.	.	.	.	.	.	.																					.												.	.	.	.	.
Template Sequence		.	.	.	.	.	.	.	.	V	Q	W	L	R	A	Q	L	G	I	V	S	Q	E	P	I	L	F	D	C	.	S	I	A	E	N	I	A	Y	G	D	N	.	.	.	.	.	S	R	V	V	S	Y	E	E	I	V	R	A	A	K	E	A	N	I	H	Q	F	I	D	S	L	P	D	K	Y	N	T	R	V	G	D
Template Known Secondary structure		.	.	.	.	.	.	.	.					T	T	S						S	S					S	S	.	B						T				S	.	.	.	.	.	S																T						S	S	T	T	T	G	G	G		B		S	T
Template Predicted Secondary structure		.	.	.	.	.	.	.	.																					.												.	.	.	.	.
Template SS confidence
										1102	.	.	.	.	.	.	.	1110	.	.	.	.	.	.	.	.	.	1120	.		.	.	.	.	.	.	.	.	1130	.	.						.	.	.	.	.	.	.	1140	.	.	.	.	.	.	.	.	.	1150	.	.	.	.	.	.	.	.	.	1160	.	.	.	.	.	.	.
		149	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		Y	P	V	H	L	S	G	G	Q	Q	Q	R	V	S	I	A	R	A	L	A	M	E	P	E	V	L	L	F	D	E	P	T	S	A	L	D	P	E	L	V	G	E	V	L	R	I	M	Q	Q	L	A	E	E	G	K	T	M	V	V	V	T	H	E	M	G	F	A	R	H	V	S	T	H	V	I	F	L	H	Q	G
Query Conservation
Alig confidence																																																					.																		.
Template Conservation																																																					.																		.
Template Sequence		K	G	T	Q	L	S	G	G	Q	K	Q	R	I	A	I	A	R	A	L	V	R	Q	P	H	I	L	L	L	D	E	A	T	S	A	L	D	T	E	S	E	K	V	V	Q	E	A	L	D	K	A	R	.	E	G	R	T	C	I	V	I	A	H	R	L	S	T	I	Q	N	.	A	D	L	I	V	V	I	Q	N	G
Template Known Secondary structure		T	S		S	S																			S	S					S		S	S	S																	S	.	S	S	S							S		T	T	G	G	G	S	.		S							T	B
Template Predicted Secondary structure																																																					.																		.
Template SS confidence
		1168	.	1170	.	.	.	.	.	.	.	.	.	1180	.	.	.	.	.	.	.	.	.	1190	.	.	.	.	.	.	.	.	.	1200	.	.	.	.	.	.	.	.	.	1210	.	.	.	.	.	.	.	.		.	1220	.	.	.	.	.	.	.	.	.	1230	.	.	.	.	.		.	.	.	.	1240	.	.	.	.	.
		229	230	.	.	.	.	.	.	.	.	.	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.
Predicted Secondary structure
Query SS confidence
Query Sequence		K	I	E	E	E	G	A	P	E	Q	L	F	G	N	P	Q	S	P	R	L	Q	R	F	L	K	G	S
Query Conservation
Alig confidence																.	.
Template Conservation																.	.
Template Sequence		K	V	K	E	H	G	T	H	Q	Q	L	L	A	Q	.	.	K	G	I	Y	F	S	M	V	S	V	Q
Template Known Secondary structure															S	.	.		S
Template Predicted Secondary structure																.	.
Template SS confidence
		1246	.	.	.	1250	.	.	.	.	.	.	.	.	.			1260	.	.	.	.	.	.	.	.	.	1270

---

Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions