|   |
3 | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | |
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Sequence |   |
E | K | T | D | V | H | W | S | G | R | F | S | V | A | P | M | L | D | W | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
T | D | R | H | C | R | Y | F | L | R | L | L | S | R | N | T | L | L | Y | T | E | M | V | T | T | G | A | I | I | H | G | K | G | D | Y | L | A | Y | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Query Conservation |   |
  |   |   |   |
|   |
|   |
|
|
|   |
|
|
|
|   |
|
| . | . | . | . | . | . | . | . | . | . |
|
|   |   |
|
|   |
|   |
|   |   |
|   |   |   |
|   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . |
Template Conservation |   |
  |
|
|   |   |   |
|
|
|
|
|
|   |
|
|
|   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |   |
|
|   |   |
|
|   |
| . |
|
|
|
|   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |
|   |
|   |
Template Sequence |   |
K | L | G | R | Y | T | L | R | N | R | I | I | M | A | P | L | T | R | C | Q | A | T | E | D | D | H | V | P | R | T | E | S | M | L | K | Y | Y | E | D | R | A | S | A | . |
G | L | I | I | A | E | A | T | M | V | Q | P | N | Y | T | G | F | L | T | E | P | G | I | Y | S | D | A | Q | I | E | E | W | R | K | I | V |
Template Known Secondary structure |   |
 |  | T | T |  |  |  | S |
| S |  |  |  |
|
|
|
|
|
|
| B |
| T | T | T |
|
| B |
|  |  |  |  |  |  |  |  |  | T | T | T | T | S | . | S |  |  |  |  |  |  |  |  | S | S | T | T |
|
| S | S | S | S |
|
| B | S | S | S |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |
|
|  |  |  |
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
|
| . |
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | |
. | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . | . | 90 |
  |
  |   |
|
|
|
60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. |
Predicted Secondary structure |   |
. | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
|
Query Sequence |   |
. |
. |
. |
S | E | E | E | H | P | V | A | L | Q | L | G | G | S | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D |
Query Conservation |   |
. | . | . |   |   |   |   |   |
|   |   |
|
|
|   |
|   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
Template Conservation |   |
  |   |
|
|   |   |
|   |   |
|   |   |
|
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|
|   |   |
|
|   |
|
Template Sequence |   |
D | A | V | H | K | K | G | G | L | I | F | L | Q | L | I | H | A | G | R | A | G | I | P | E | K | I | L | Q | Q | S | K | S | D | Q | D | P | L | A | G | R | L | L | A | A | S | A | I | P | I | K | D | H | R | I | P | A | Y | F | A | A | S | G | E | K | E | T | Y | G | V | P | E | E | L | T | D | D | E | V | R | D |
Template Known Secondary structure |   |
 |  |  |  |  | T | T |
|
|  |  |  |  |  |  |
|
| G | G | G | S |
|  |  |  |  | T | T | S |
|
|
| S | S | S | T | T | T | T |
|
|  |  | S | S | S |
|
|
|
| S |
|
| B |
| T | T | T | S | T | T | S | S |
| B |
|
|
|
|
|  |  |
|
|  |  |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
91 | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 |
  |
  |   |
|
|
75 | . | . | . | . | 80 | . | . | . | . | . | . | |
. | . | . | 90 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
100 | . | . | . | . | . | . | . | . | |
|
. | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 |
Predicted Secondary structure |   |
. | . |  |  |  |  |  |  |  |  |  |  |  |  | . |  |
|
|
|
|  |  |  |  |
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|  |  |
|
|
|
| . | . |
|
|
|  |  |  |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
P | A | A | L | A | Q | C | A | K | L | A | E | . |
A | R | G | Y | D | E | I | N | L | N | V | G | C | . |
. |
. |
. |
. |
. |
. |
. |
. |
P | S | D | R | V | Q | N | G | M | . |
. |
F | G | A | C | L | M | G | N | A | Q | L | V | A | D | C | V | K | A | M | R | D | V | V | S | I | P | V | T | V | K | T | R |
Query Conservation |   |
. | . |
|   |   |   |   |   |
|
|   |   |   |   | . |   |   |
|   |
|   |
|
|
|
|   |
|
| . | . | . | . | . | . | . | . | . |
|   |   |   |   |   |   |   |   | . | . |   |
|   |   |
|   |   |   |   |   |   |   |   |
|
|
|   |
|
|
|   |   |   |   |   |
|
|   |
|
|
|
|
Alig confidence |   |
. | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
Template Conservation |   |
  |
|
|   |   |
|   |   |
|
|   |
|
|   |   |   |
|
|
|
|
|
|
|
|
|   |
|
|
|
|
|
|   |
|
|
|
|
|   |   |
|   |
|
|
|   |
|   |
|
|
|
|   |
|
|
|   |
|
|   |   |
|
|
|   |
|
|
|   |   |
|
|   |
|   | . |
|   |   |
|
Template Sequence |   |
G | I | I | P | L | F | V | E | G | A | K | N | A | I | F | K | A | G | F | D | G | V | E | I | H | G | A | N | G | Y | L | L | D | A | F | F | R | E | S | S | N | K | R | Q | S | G | P | Y | A | G | T | T | I | D | T | R | C | Q | L | I | Y | D | V | T | K | S | V | C | D | A | V | G | S | D | R | . |
V | G | L | R |
Template Known Secondary structure |   |
T |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | S |
|
| S |  |  |  |  |  |  |
| T | T | S |  |  |  |  |  |  | S | T | T | T |
|
|
|
| S | S | T | T |
| T | T | S |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G | . |  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  | . |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
171 | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | |
. | . | . | . |
  |
  |   |
141 | . | . | . | . | . | . | |
|
|
|
|
|
|
. | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | G | I | D | D | Q | D | . |
. |
. |
. |
. |
. |
. |
S | Y | E | F | L | C | D | F | I | N | T | V | S | G | K | G | E | C | E | M | F | I | I | H | A | R | K | A | W | L | S | G | L | S | P | K | E | N | R | E | I | P | P | L | D | Y | P | R | V | Y | Q | L | K | R | D | F | P | H | L | T | M | S | I | N | G | G |
Query Conservation |   |
|
|   |
|   |   |   | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|
|   |   |
|   |
|
|   |
|   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |
|
|
|
|   |
|
|   |
Alig confidence |   |
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
| . |
Template Conservation |   |
|
|   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
| . |
|   |   |
|
|
|   |
|   |
|
|   |
| . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   | . |   |   |   |   |
|   |   |
| . |
Template Sequence |   |
I | S | P | L | N | G | V | H | G | M | I | D | S | N | P | E | A | L | T | K | H | L | C | K | K | I | . |
E | P | L | S | L | A | Y | L | H | Y | L | R | G | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
D | M | V | N | Q | Q | I | G | D | V | V | A | W | V | R | G | S | Y | . |
S | G | V | K | I | S | N | L | . |
Template Known Secondary structure |   |
 |
| T | T |
|
| G | G | G |
|
|
| S |
|  |  |  |  |  |  |  |  |  |  |  |  | . | G | G | G |
|
| S |  |  |  |  |  |
| S | . | . | . | . | . | . | . | . | . | . | . | . |
| T | T | S |
|
|
|
|
|  |  |  |  |  |  | T | T |
| . |
| S |
|  |  |  |  | S | . |
Template Predicted Secondary structure |   |
 |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  | . |  |  |
|
|
|
|  |  |  |  |
|
|
| . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
| . |
|
|  |  |  |  |
|
| . |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | |
. | . | . | . | 280 | . | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
. | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | |
. | . | . | 310 | . | . | . | . | |
  |
  |   |
214 | . | . | . | . | . | 220 | . | . | . | . | . | . | |
|
. | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | . | . | 260 | . |
Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |  | . | . |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | K | S | L | E | E | A | K | A | H | L | Q | H | . |
. |
M | D | G | V | M | V | G | R | E | A | Y | Q | N | P | G | I | L | A | A | V | D | R | E | I | F | G | S | S | D | T | D | A | D | P | V |
Query Conservation |   |
|   |
|   |   |
|
|   |   |   |
|   |   | . | . |   |
|   |
|
|
|
|
|   |   |
|   |
|
|   |
|
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
| . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |
|   |
|   |   |
|
|   |   |
|
|
|
|
|
|   |   |
|   |   |   | . | . | . |
|   |   |
|   |   |   |   |
|   |
Template Sequence |   |
R | Y | D | F | E | E | A | D | Q | Q | I | R | E | G | K | V | D | A | V | A | F | G | A | K | F | I | A | N | P | D | L | V | E | R | A | Q | Q | . |
. |
. |
N | W | P | L | N | E | P | R | P | E |
Template Known Secondary structure |   |
S |
|
|  |  |  |  |  |  |  |  |  | T | T | S |
| S |  |  |  |  | S |  |  |  |  |  |
| T | T |  |  |  |  |  |  |  | . | . | . | T |
|
|
|
|
|
|
| G | G |
Template Predicted Secondary structure |   |
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |
|
|
|
|  |  |  |  |  |  |  | . | . | . |
|
|
|
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
315 | . | . | . | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | |
|
|
. | . | . | . | . | . | . | . | 360 | . |
  |