Job Description P32695 Confidence 99.88% Date Thu Jan 5 11:50:18 GMT 2012 Rank 31 Aligned Residues 240 % Identity 17% Template c2fptA_ PDB info PDB header:oxidoreductase Chain: A: PDB Molecule:dihydroorotate dehydrogenase, mitochondrial; PDBTitle: dual binding mode of a novel series of dhodh inhibitors Resolution 2.40 Å

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		3	.	.	.	.	.	.	10	.	.	.	.	.	.	.	.	.	20	.	.	.	.	.	.	.	.	.	30	.	.	.	.	.	.	.	.	.	40	.	.	.	.	.	.	.
Predicted Secondary structure																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query SS confidence																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Sequence		E	K	T	D	V	H	W	S	G	R	F	S	V	A	P	M	L	D	W	T	D	R	H	C	R	Y	F	L	R	L	L	S	R	N	T	L	L	Y	T	E	M	V	T	T	G	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Query Conservation																																															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Alig confidence																															.	.															.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.	.
Template Conservation																															.	.
Template Sequence		R	V	L	G	H	K	F	R	N	P	V	G	I	A	A	G	F	D	K	H	G	E	A	V	D	G	L	Y	K	.	.	M	G	F	G	F	V	E	I	G	S	V	T	P	K	P	Q	E	G	N	P	R	P	R	V	F	R	L	P	E	D	Q	A	V	I	N	R	Y	G	F	N	S	H	G	L	S	V	V	E	H
Template Known Secondary structure				T	T				S	S	S					T	T	T	T	T	T	S	S								.	.	T	T		S									S	S		B			S		S							G	G	G	T										B
Template Predicted Secondary structure																															.	.
Template SS confidence
		82	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100	.	.	.	.	.	.	.	.	.	110			.	.	.	.	.	.	.	.	.	120	.	.	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.
		48	.	50	.	.	.	.	.	.	.	.	.	60	.	.	.	.	.	.	.	.	.	70						.	.	.	.	.	.	.	.	.	80	.	.	.	.	.	.	.	.	.	90	.	.	.	.	.	.	.	.	.	100		.	.	.	.	.	.	.	.	.	110	.	.	.	.	.	.	.	.	.	120	.
Predicted Secondary structure																									.	.	.	.	.																															.
Query SS confidence																									.	.	.	.	.																															.
Query Sequence		A	I	I	H	G	K	G	D	Y	L	A	Y	S	E	E	E	H	P	V	A	L	Q	L	.	.	.	.	.	G	G	S	D	P	A	A	L	A	Q	C	A	K	L	A	E	A	R	G	Y	D	E	I	N	L	N	V	G	C	P	.	S	D	R	V	Q	N	G	M	F	G	A	C	L	M	G	N	A	Q	L	V	A
Query Conservation																									.	.	.	.	.																															.
Alig confidence																									.	.	.	.	.																			.												.
Template Conservation																																																.
Template Sequence		R	L	R	A	R	Q	Q	K	Q	A	K	L	T	E	D	G	L	P	L	G	V	N	L	G	K	N	K	T	S	V	D	A	A	E	D	Y	A	E	G	V	R	V	L	G	P	L	.	A	D	Y	L	V	V	N	V	S	S	P	N	T	A	G	L	R	S	L	Q	G	K	A	E	L	R	R	L	L	T	K	V	L
Template Known Secondary structure					T	T										T	T											T	T		S														G	G	G	.		S									T	T	S	T	T	S	G	G	G	G	S
Template Predicted Secondary structure																																																.
Template SS confidence
		160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.	190	.	.	.	.	.	.	.	.	.	200	.	.	.	.	.		.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.	.	.	.	.	230	.	.	.	.	.	.	.	.
		122	.	.	.	.	.	.	.	130	.	.	.	.	.	.	.	.	.	140	.	.	.	.	.	.	.	.	.	150	.	.	.	.	.	.	.	.	.	160	.	.	.	.	.	.	.	.	.	170	.	.	.	.	.	.	.	.	.	180	.	.	.	.	.	.	.	.	.										190	.	.
Predicted Secondary structure																																																																						.	.	.	.	.	.	.	.	.
Query SS confidence																																																																						.	.	.	.	.	.	.	.	.
Query Sequence		D	C	V	K	A	M	R	D	V	V	S	I	P	V	T	V	K	T	R	I	G	I	D	D	Q	D	S	Y	E	F	L	C	D	F	I	N	T	V	S	G	K	G	E	C	E	M	F	I	I	H	A	R	K	A	W	L	S	G	L	S	P	K	E	N	R	E	I	P	.	.	.	.	.	.	.	.	.	P	L	D
Query Conservation																																																																						.	.	.	.	.	.	.	.	.
Alig confidence																												.	.	.	.	.																																						.	.	.	.	.	.	.	.	.
Template Conservation																												.	.	.	.	.
Template Sequence		Q	E	R	D	G	L	R	R	V	H	R	P	A	V	L	V	K	I	A	P	D	L	T	S	Q	D	.	.	.	.	.	K	E	D	I	A	S	V	V	K	E	L	G	I	D	G	L	I	V	T	N	T	T	V	S	R	P	A	G	L	Q	G	A	L	R	S	E	T	G	G	L	S	G	K	P	L	R	D	L	S
Template Known Secondary structure						T	S		G	G	G										S							.	.	.	.	.												T										B	S				T	T				T	T	T	T	S	S	S
Template Predicted Secondary structure																												.	.	.	.	.
Template SS confidence
		239	240	.	.	.	.	.	.	.	.	.	250	.	.	.	.	.	.	.	.	.	260	.	.	.	.						.	.	.	.	.	270	.	.	.	.	.	.	.	.	.	280	.	.	.	.	.	.	.	.	.	290	.	.	.	.	.	.	.	.	.	300	.	.	.	.	.	.	.	.	.	310	.	.	.
		193	.	.	.	.	.	.	200	.	.	.	.		.	.	.	.	.	210	.	.	.	.	.	.	.	.	.	220	.	.	.	.	.		.	.	.	.	230	.	.	.	.	.	.	.		.	.	240	.	.	.	.	.	.	.	.	.	250
Predicted Secondary structure														.																						.													.
Query SS confidence														.																						.													.
Query Sequence		Y	P	R	V	Y	Q	L	K	R	D	F	P	.	H	L	T	M	S	I	N	G	G	I	K	S	L	E	E	A	K	A	H	L	Q	.	H	M	D	G	V	M	V	G	R	E	A	Y	.	Q	N	P	G	I	L	A	A	V	D	R	E	I
Query Conservation														.																						.													.
Alig confidence														.																						.													.
Template Conservation
Template Sequence		T	Q	T	I	R	E	M	Y	A	L	T	Q	G	R	V	P	I	I	G	V	G	G	V	S	S	G	Q	D	A	L	E	K	I	R	A	G	A	S	L	V	Q	L	Y	T	A	L	T	F	W	G	P	P	V	V	G	K	V	K	R	E	L
Template Known Secondary structure												T	T	T		S						S	S			S											T		S					S								T
Template Predicted Secondary structure
Template SS confidence
		314	.	.	.	.	.	320	.	.	.	.	.	.	.	.	.	330	.	.	.	.	.	.	.	.	.	340	.	.	.	.	.	.	.	.	.	350	.	.	.	.	.	.	.	.	.	360	.	.	.	.	.	.	.	.	.	370	.	.	.	.

No model constructed - rank, confidence too low

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Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
© Structural Bioinformatics Group, Imperial College, London Lawrence Kelley, Benjamin Jefferys   Disclaimer Terms and Conditions