|   |
9 | 10 | . | . | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . | 80 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | E | I | Y | R | A | L | I | A | T | P | S | I | S | A | T | E | E | A | L | D | Q | S | N | A | D | L | I | T | L | L | A | D | W | F | K | D | L | G | F | N | V | E | V | Q | P | V | P | G | T | R | N | K | F | N | M | L | A | S | I | G | Q | G | A | G | G | L | L | L | A | G | H | T | D | T | V | P | F | D | D |
Query Conservation |   |
|   |   |
|   |   |
|
|   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |
|   |
|
|
|
|   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |
|
|   |   |
|
|   |
|
|
|
|
|
|   |
|
| . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |   |
|   |   |   |
|   |   |
|   |   |
|   |   |
| . | . | . | . | . | . |
|
|
|
|   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |
|
|
|   |   |   |   |
Template Sequence |   |
W | K | L | M | Q | E | I | I | E | A | P | G | V | S | G | Y | E | H | . |
. |
. |
. |
. |
. |
L | G | I | R | D | I | V | V | D | V | L | K | E | V | A | D | E | V | K | V | D | K | L | G | . |
. |
. |
. |
. |
. |
N | V | I | A | H | F | K | G | S | S | P | R | I | M | V | A | A | H | M | D | K | I | G | V | M | V |
Template Known Secondary structure |   |
 |  |  |  |  |  |  |  |  | S |
|
| B | T | T |
| G | G | . | . | . | . | . | . | G | T |  |  |  |  |  |  |  |  |  |  | T | T |
| S |  |  |  |  |
| T | T |
| . | . | . | . | . | . |
|  |  |  |  |  |
|
| S | S | S |  |  |  |  |  |  |  |
|
| B |
|  |  |  |  |
Template Predicted Secondary structure |   |
 |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |
|
|
| . | . | . | . | . | . |
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
12 | . | . | . | . | . | . | . | 20 | . | . | . | . | . | . | . | . | . | |
|
|
|
|
|
30 | . | . | . | . | . | . | . | . | . | 40 | . | . | . | . | . | . | . | . | . | 50 | . | . | . | |
|
|
|
|
|
. | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . | . | . |
  |
  |   |
89 | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | . | . | . | . | . | . | . | 150 | . | . | . | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
G | R | W | T | R | D | P | F | T | L | T | E | H | D | G | K | L | Y | G | L | G | T | A | D | M | K | G | F | F | A | F | I | L | D | A | L | R | D | V | D | V | T | K | L | K | K | P | L | Y | I | L | A | T | A | D | E | E | T | S | M | A | G | A | R | Y | F | A | E | T | T | A | L | R | P | D | C | A | I | I | G |
Query Conservation |   |
  |   |
|   |   |   |
|   |   |   |   |   |   |   |
|   |
|   |
|
|
|   |   |
|   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|
|   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
Alig confidence |   |
|
|
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |
|   | . | . | . | . | . | . |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |
|   |   |   |   |   |   |   |
|   |   |
|   |
|   |   |   |   |   |   |   |
|   |   |   |   |   |
|   |   |   |   |   |
Template Sequence |   |
N | H | I | D | K | D | G | Y | . |
. |
. |
. |
. |
. |
L | H | I | V | P | I | G | G | V | L | P | E | T | L | V | A | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
Q | R | I | R | F | F | T | E | K | G | E | R | Y | G | V | V | G | V | L | P | D | W | D | Q | I | V | V | D | V | G | A | S | S | K | E |
Template Known Secondary structure |   |
 |  |  |
| T | T | S |
| . | . | . | . | . | . |  |  |  |  |  |  | S | S |
|
| G | G | G | G | T | T | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|  |  |  |  |  |  | T | T |  |  |  |  |  |  |  |
|
|
|
|
|
| T | T |
|  |  |  |
| S |
| S | S |  |  |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|  | . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
80 | . | . | . | . | . | . | . | |
|
|
|
|
|
. | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . |
  |
  |   |
169 | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | . | . | . | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
E | P | T | S | L | Q | P | V | R | A | H | K | G | H | I | S | N | A | I | R | I | Q | G | Q | S | G | H | S | S | D | P | A | R | G | V | N | A | I | E | L | M | H | D | A | I | G | H | I | L | Q | L | R | D | N | L | K | E | R | Y | H | Y | E | A | F | T | V | P | Y | P | T | L | N | L | G | H | I | H | G | G | D |
Query Conservation |   |
  |   |   |   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |
|   |
|   |
|   |   |   |
|
|
|   |   |   |   |   |   |
|
|
|   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |
|   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . |
|
|
Template Conservation |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . |   |   |
Template Sequence |   |
E | A | E | E | M | G | F | R | V | G | T | V | G | E | F | A | P | N | F | T | R | L | N | E | H | R | F | A | T | P | Y | L | D | D | R | I | C | L | Y | A | M | I | E | A | A | R | Q | L | G | D | H | E | A | D | I | Y | I | V | G | S | V | Q | E | E | V | G | L | R | G | A | R | . |
. |
. |
. |
. |
. |
. |
V | A |
Template Known Secondary structure |   |
 |  |  |  | T | T |
|
| T | T |
|  |  |  |  |
|
|
|
|  |  |
| S | S | S |  |  |  |
| T | T |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|
| S | S |  |  |  |  |  |  |  | S | S |
| T | T | T | S |  |  |  |  | . | . | . | . | . | . | . |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|  |  |  |  |  |  |  |
|
|
| . | . | . | . | . | . | . |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
153 | . | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | . | . | . | . | . | 220 | . | . | . | |
|
|
|
|
|
|
. | . |
  |
  |   |
249 | 250 | . | . | . | . | . | . | . | . | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . | 290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | . | . | 320 | . | . | . | . | . | . | . | |
Predicted Secondary structure |   |
 |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  | . |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Query Sequence |   |
A | S | N | R | I | C | A | C | C | E | L | H | M | D | I | R | P | L | P | G | M | T | L | N | E | L | N | G | L | L | N | D | A | L | A | P | V | S | E | R | W | P | G | R | L | T | V | D | E | L | H | P | P | I | P | G | Y | E | C | P | P | N | H | Q | L | V | E | V | V | E | K | L | L | G | A | K | T | E | V | . |
Query Conservation |   |
  |   |
|   |
|
|   |   |
|   |   |   |   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   | . |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
S | Y | A | I | N | P | E | V | G | I | A | M | D | V | T | F | A | K | Q | P | H | D | K | G | K | I | V | P | E | L | G | K | . |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
. |
G | P | V | M | D | V | G | P | N | I | N | P | K | L | R | A | F | A | D | E | V | A | K | K | Y | E | I | P | L | Q | V | E |
Template Known Secondary structure |   |
 |  |  |  |
|
| S |  |  |  |  |  |  |  |  |  |
|
|
| T | T |
| T | T |
|
|
|
|
| T | T | S | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |
|
|  |  |  |  | S | T | T | S |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  | T |
|
|
|  |  |  |
Template Predicted Secondary structure |   |
|  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . | . |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
226 | . | . | . | 230 | . | . | . | . | . | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . | 250 | . | . | . | . | . | . | . | |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
. | . | 260 | . | . | . | . | . | . | . | . | . | 270 | . | . | . | . | . | . | . | . | . | 280 | . | . | . | . | . | . | . | . | . |
  |
  |   |
|
|
|
328 | . | 330 | . | . | . | . | . | . | . | |
|
|
. | . | 340 | . | . | . | . | . | . | . | . | . | 350 | . | . | . | . | . | . | . | . | . | 360 | . | . | . | . | . | . | . | . | . | 370 | . | . | . | . | . | . | . | . | . | 380 |
Predicted Secondary structure |   |
. | . | . |  |  |
|
|
|  |  |  |  |  | . | . | . |  |  |  |
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Query SS confidence |   |
. |
. |
. |
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
. |
. |
. |
V | N | Y | C | T | E | A | P | F | I | . |
. |
. |
Q | T | L | C | P | T | L | V | L | G | P | G | S | I | N | Q | A | H | Q | P | D | E | Y | L | E | T | R | F | I | K | P | T | R | E | L | I | T | Q | V | I | H | H | F |
Query Conservation |   |
. | . | . |   |   |
|   |
|
|   |   |   |   | . | . | . |   |   |
|   |
|   |   |   |   |
|
|
|   |   |   |   |   |
|   |   |   |
|   |
|   |   |   |   |
|   |   |   |   |   |   |
|   |   |   |
|   |   |   |
Alig confidence |   |
. | . | . |
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |
|
|
|
|   |   |   |   |   |   |   |   |   |
|
|
|
|
|   |   |
|   |
| . |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |
|   |   |   |   |   |
|
|   |   |   |
|   |   |
|
Template Sequence |   |
P | S | P | R | P | T | G | T | D | A | N | V | M | Q | I | N | R | E | G | V | A | T | A | V | L | S | I | P | . |
I | R | Y | M | H | S | Q | V | E | L | A | D | A | R | D | V | D | N | T | I | K | L | A | K | A | L | L | E | E | L |
Template Known Secondary structure |   |
 |
|
| S |
|
| S | S | T |  |  |  |  |  | T | S | T | T |
|
|  |  |  |  |  |  |  |  | . |  | B | S | T | T | S | T | T |
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
| . |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
290 | . | . | . | . | . | . | . | . | . | 300 | . | . | . | . | . | . | . | . | . | 310 | . | . | . | . | . | . | . | |
. | . | 320 | . | . | . | . | . | . | . | . | . | 330 | . | . | . | . | . | . | . | . | . | 340 | . | . | . | . | . | . | . |
  |