|   |
2 | . | . | . | . | . | . | . | 10 | . | . | . | . | . | . | . | . | . | 20 | . | |
. | . | . | . | . | . | . | . | 30 | . | . | . | . | . | . | . | . | . | 40 | . | . | |
|
|
. | . | . | . | . | . | . | 50 | . | . | . | . | . | . | . | . | . | 60 | . | . | . | . | . | . | . | . | . | 70 | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
| . |
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
I | E | I | E | S | R | E | L | A | D | I | P | V | L | H | A | Y | P | V | G | . |
Q | K | D | T | P | L | P | C | V | I | F | Y | H | G | F | T | S | S | S | L | V | . |
. |
. |
Y | S | Y | F | A | V | A | L | A | Q | A | G | L | R | V | I | M | P | D | A | P | D | H | G | S | R | F | S | G | D | A | A | R | R | L |
Query Conservation |   |
|   |
|   |   |   |
|
|   |   |
|   |   |   |   |   |   |
|   |   | . |   |   |   |   |   |   |
|   |
|
|   |   |
|
|   |   |   |   |   |   |   | . | . | . |   |   |   |   |   |   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
|   |   |   |
|   |
|
|   |   |
|   |   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |
|   |   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
I | F | Y | P | S | K | D | G | T | K | I | P | M | F | I | V | H | K | K | G | I | K | L | D | G | S | H | P | A | F | L | Y | G | Y | G | G | F | N | I | S | I | T | P | N | Y | S | V | S | R | L | I | F | V | R | H | M | G | G | V | L | A | V | A | N | I | R | G | G | G | E | Y | G | E | T | W | H | K | G | G | I |
Template Known Secondary structure |   |
 |  |  |  |
| T | T | S |
|  |  |  |  |  |  |  |  |  | T | T |
|
|
| S | S |
| S |
|  |  |  |  |
|
|
|
| T | T |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|  |  |  |  |  |
|
| T | T | S | S | T | T |  |  |  |  |  |  | T | T | S |
Template Predicted Secondary structure |   |
 |  |  |  |
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
440 | . | . | . | . | . | . | . | . | . | 450 | . | . | . | . | . | . | . | . | . | 460 | . | . | . | . | . | . | . | . | . | 470 | . | . | . | . | . | . | . | . | . | 480 | . | . | . | . | . | . | . | . | . | 490 | . | . | . | . | . | . | . | . | . | 500 | . | . | . | . | . | . | . | . | . | 510 | . | . | . | . | . | . | . | . | . |
  |
  |   |
78 | . | 80 | . | . | . | . | . | . | . | . | . | 90 | . | . | . | . | . | . | . | . | . | 100 | . | . | . | . | . | . | . | . | . | 110 | . | . | . | . | . | . | . | . | . | 120 | . | . | . | . | . | . | . | . | . | 130 | . | . | . | . | . | . | . | . | . | 140 | . | . | |
|
|
|
. | . | . | . | . | . | . | 150 | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |  |
|
|
|
| . | . | . | . |  |  |  |  |  |  |  |
|
|  |  |
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
N | Q | F | W | Q | I | L | L | Q | S | M | Q | E | F | T | T | L | R | A | A | I | A | E | E | N | W | L | L | D | D | R | L | A | V | G | G | A | S | M | G | A | M | T | A | L | G | I | T | A | R | H | P | T | V | R | C | T | A | S | M | M | G | S | G | Y | . |
. |
. |
. |
F | T | S | L | A | R | S | L | F | P | P |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |
|   |
|   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |
Alig confidence |   |
|
|
|
|
|
| . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   | . | . | . |   |   |   |
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
Template Sequence |   |
L | A | N | K | Q | N | . |
. |
. |
C | F | D | D | F | Q | C | A | A | E | Y | L | I | K | E | G | Y | T | S | P | K | R | L | T | I | N | G | G | S | N | G | G | L | L | V | A | T | C | A | N | Q | R | P | D | L | F | G | C | V | I | A | Q | V | G | V | M | D | M | L | K | F | H | K | Y | T | I | G | H | A | W | T |
Template Known Secondary structure |   |
G | G | G | T |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | S |
|
| G | G | G |  |  |  |  |  |  | T |  |  |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
| S |  |  |  |  |  | S |
|
|
|
| T | T | T | G | G | G | S | T | T | G | G | G | G |  |
Template Predicted Secondary structure |   |
|
|
|  |  |  | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|  |  |  |
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
520 | . | . | . | . | . | |
|
|
. | . | . | . | 530 | . | . | . | . | . | . | . | . | . | 540 | . | . | . | . | . | . | . | . | . | 550 | . | . | . | . | . | . | . | . | . | 560 | . | . | . | . | . | . | . | . | . | 570 | . | . | . | . | . | . | . | . | . | 580 | . | . | . | . | . | . | . | . | . | 590 | . | . | . | . | . | . |
  |
  |   |
154 | . | . | . | . | . | 160 | . | . | . | . | . | . | . | . | . | 170 | . | . | . | . | . | . | . | . | . | 180 | . | . | . | . | . | . | . | . | . | 190 | . | . | . | . | . | . | . | . | . | 200 | . | . | . | . | . | . | . | . | . | 210 | . | . | . | . | |
|
|
|
|
. | . | . | . | . | 220 | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |  |
|
|
|
|
|
|
|
|
|
|
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  | . | . | . | . | . |
|
|
|
|
|  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
L | I | P | E | T | A | A | Q | Q | N | E | F | N | N | I | V | A | P | L | A | E | W | E | A | T | N | H | L | E | Q | L | S | D | R | P | L | L | L | W | H | G | L | D | D | D | V | V | P | A | D | E | S | L | R | L | Q | Q | A | L | S | E | . |
. |
. |
. |
. |
T | G | R | D | K | L | L | T | C | S | W | Q | P | G |
Query Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|   |   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   | . | . | . | . | . |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
Alig confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
| . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|   |
|
|   |   |
|   |   |
|   |   |
|   |   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |   |   |   |   |   |   |
|   |   |   |   |
|   |   |   |   |
|
Template Sequence |   |
T | D | Y | G | S | D | S | K | Q | H | F | E | W | L | I | K | Y | S | P | L | H | N | V | K | L | P | E | A | D | D | I | Q | Y | P | S | M | L | L | L | T | A | D | H | D | D | R | V | V | P | L | H | S | L | K | F | I | A | T | L | Q | Y | I | V | G | R | S | R | K | Q | N | N | P | L | L | I | H | V | D | T | K |
Template Known Secondary structure |   |
 |  |  |
|
|
| S |  |  |  |  |  |  |  |  |  |  |
| G | G | G |
|
|
|
|
| S | S | T | T |
|
|
|
|  |  |  |  |  |  |  | T | T |
|
| S | S |
| T |  |  |  |  |  |  |  |  |  |  |  |  |  | T | T | T | S | T | T |
|
| S |
|  |  |  |  |  |  | S | S |
Template Predicted Secondary structure |   |
 |  |  |
|
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
|
|  |  |  |  |  |  |
|
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
597 | . | . | 600 | . | . | . | . | . | . | . | . | . | 610 | . | . | . | . | . | . | . | . | . | 620 | . | . | . | . | . | . | . | . | . | 630 | . | . | . | . | . | . | . | . | . | 640 | . | . | . | . | . | . | . | . | . | 650 | . | . | . | . | . | . | . | . | . | 660 | . | . | . | . | . | . | . | . | . | 670 | . | . | . | . | . | . |
  |
  |   |
229 | 230 | . | . | . | . | |
|
|
|
|
|
. | . | . | . | . | 240 | . | . | . | . | . | . | . | . | . |
Predicted Secondary structure |   |
|
|
|
|
|
| . | . | . | . | . | . |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
|
Query SS confidence |   |
|
|
|
|
|
| . |
. |
. |
. |
. |
. |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Query Sequence |   |
V | R | H | R | I | T | . |
. |
. |
. |
. |
. |
P | E | A | L | D | A | A | V | T | F | F | R | Q | H | L |
Query Conservation |   |
  |   |
|   |   |   | . | . | . | . | . | . |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
Alig confidence |   |
|
|
|
|
|
| . | . | . | . | . | . |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Template Conservation |   |
  |
|
|   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |   |
|
|   |   |   |
|
Template Sequence |   |
A | G | H | G | A | G | K | P | T | A | K | V | I | E | E | V | S | D | M | F | A | F | I | A | R | C | L |
Template Known Secondary structure |   |
|
| S | S | T | T |
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Template Predicted Secondary structure |   |
|
|
|
|
|
|
|
|  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
|
Template SS confidence |   |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
  |   |
678 | . | 680 | . | . | . | . | . | . | . | . | . | 690 | . | . | . | . | . | . | . | . | . | 700 | . | . | . | . |
  |