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Job DescriptionP39298
Confidence99.29%DateThu Jan 5 11:59:04 GMT 2012
Rank215Aligned Residues202
% Identity15%Templatec2px6A_
PDB info PDB header:transferaseChain: A: PDB Molecule:thioesterase domain; PDBTitle: crystal structure of the thioesterase domain of human fatty2 acid synthase inhibited by orlistat
Resolution2.30 Å

  Insertion relative to template
  Deletion relative to template
  Catalytic residue from the CSA
 
Detailed help on interpreting your alignment


   13......20.........30.........40.........50.........60.........70.........80.........90..
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Query Sequence  PVLHAYPVGQKDTPLPCVIFYHGFTSSSLVYSYFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFT
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Template Sequence  PTLMRLNSVQSSER. . PLFLVHPIEGSTTVFHSLASRL. . . SIPTYGLQCTRAAPLD. . . . . . . . . . . . . . . . SIHSLAA
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   22292230.........2240.. .......2250.........2260.... .....2270.........2280 .......
 
   93......100.........110.........120....... ..130.........140.....
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Query Sequence  TLRAAIAEENWLLDDRLAVGGASMGAMTALGITAR. . . . HPTVRCTASMMGSGYFTS. . . . . . . . . . . . . . . . . . . . . . .
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Template Sequence  YYIDCIRQVQPEGP. . YRVAGYSYGACVAFEMCSQLQAQQPTHNSLFLFDGSPTYAEAETEAICFFVQQFTDMEHNRVLE
Template Known Secondary structure  TTT
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   2288.2290.........2300. ........2310.........2320.........2330.........2340.........2350.........2360.....
 
   146...150.........160.........170.........180.........190.........200.........210.
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Query Sequence  . . . . . . . . . . . . . . LARSLFPPLIPETAAQQNEFNNIVAPLAEWEATNHLEQLSDRPLLLWHGLDDDVVPADESLRLQQA
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Template Sequence  ALLPLKGLEERVAAAVDLIIKSHQGLDRQELSFAARSFYYKLRAAEQYTPKAKYHGNVMLLRAKTGADYNL. . . . . . . . .
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   2386...2390.........2400.........2410.........2420.........2430.........2440.........2450......
 
   212.......220.........230.. .......240.........
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Query Sequence  LSETGRDKLLTCSWQPGVRHR. . ITPEALDAAVTFFRQHL
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Template Sequence  . . SQVCDGKVSVHVIEG. DHRTLLEGSGLESIISIIHSSL
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   2465....2470......... 2480.........2490.........2500.
 
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No model constructed - rank, confidence too low




Phyre is for academic use only

Please cite: Protein structure prediction on the web: a case study using the Phyre server
Kelley LA and Sternberg MJE. Nature Protocols 4, 363 - 371 (2009) [pdf] [Import into BibTeX]
 
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Lawrence Kelley, Benjamin Jefferys 
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